Patents by Inventor Corrado Mandoli

Corrado Mandoli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIGHLY POROUS SOLID MATERIAL MADE OF BIODEGRADABLE POLYMER AND METHOD OF FABRICATING, PROCESSING, AND CELL-SEEDING THE SAME
    Publication number: 20110171732
    Abstract: [Problems] A purpose of the invention is to provide highly porous 3D scaffolds made of biodegradable polymer such as poly-lactic acid, which can be preferably used for cell culture. Another purpose of this invention is to provide a method for seeding cells homogeneously inside the above mentioned 3D highly porous scaffolds. Another purpose of this invention is to provide a top-down processing method for obtaining planar porous 2D scaffolds starting the above mentioned highly porous scaffolds to be used as building blocks for thick tissue reconstruction. [Solution] Highly porous scaffolds made of biodegradable polymer such as poly-lactic acid can be fabricated by following steps: (i) biodegradable polymer is dissolved in dioxane at the defined concentration; (ii) a vessel containing the solution is mounted on a metal plate thermally driven by a cold finger to a defined temperature below 10° C.
    Type: Application
    Filed: November 1, 2010
    Publication date: July 14, 2011
    Inventors: Corrado Mandoli, Enrico Traversa