Patents by Inventor Cortland J. Lohff

Cortland J. Lohff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vectors for cloning and modification of DNA fragments
    Patent number: 5827704
    Abstract: Plasmid vectors are provided which enable for the modification of double-stranded DNA which has blunt or one-base 3' overhanging termini, to include any desired four-base 5' overhang sequence, in the reading frame of choice. These vectors enable the cloning of blunt double-stranded DNA sequences or double-stranded DNA sequences having a one-base 3' overhang into a unique restriction site by blunt-end ligation or by one-base 3' overhang cohesive cloning such as T-cloning. The vectors may be amplified and subsequently excised, thereby producing modified fragments free of vector sequences.
    Type: Grant
    Filed: February 28, 1996
    Date of Patent: October 27, 1998
    Assignee: The Regents Of The University Of Michigan
    Inventors: Kemp B. Cease, Cortland J. Lohff