Patents by Inventor Corwin F. Kostrub

Corwin F. Kostrub has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AMINOGLYCOSIDE DOSING REGIMENS
    Publication number: 20120208781
    Abstract: The present invention provides new aminoglycoside dosing regimens associated with enhanced microbicidal activity and reduced nephrotoxicity, as well as methods of using these dosing regimens to treat various bacterial infections.
    Type: Application
    Filed: November 11, 2011
    Publication date: August 16, 2012
    Applicant: Achaogen, Inc.
    Inventors: Jon B. Bruss, Corwin F. Kostrub, Eliana Saxon Armstrong, Robert T. Cass, George H. Miller, James Bradley Aggen, Adam Aaron Goldblum, Paola Dozzo, Martin Sheringham Linsell
  • COMPOSITIONS AND METHODS FOR DETERMINING NEPHROTOXICITY
    Publication number: 20090220982
    Abstract: The present invention provides novel in vitro assays for determining the nephrotoxicity of a compound. These assays correlate well with in vivo nephrotoxicity and also provide high-throughput methods to screen multiple compounds for in vivo nephrotoxicity. In addition, the methods of the present invention may be adapted to screen for nephroprotectant compounds, including those that protect cells and animals from the nephrotoxic effects of aminoglycoside antibiotics.
    Type: Application
    Filed: February 24, 2009
    Publication date: September 3, 2009
    Applicant: Achaogen Inc..
    Inventors: Eliana Saxon Armstrong, Lee Ann Feeney, Corwin F. Kostrub