Patents by Inventor Cory Alvey

Cory Alvey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Selective Phagocytosis of Human Cancer Cells
    Publication number: 20210220401
    Abstract: The present invention relates to compositions and methods that provide novel therapies in cancer. The invention includes a phagocytic cell modified with a repressor of signal regulatory protein-alpha (SIRP?) and bound to a targeting antibody to enhance phagocytic activity of the phagocytic cell toward tumor tissue. Methods of enhancing phagocytic activity and treating a tumor are also included.
    Type: Application
    Filed: March 10, 2021
    Publication date: July 22, 2021
    Inventors: Dennis E. Discher, Kyle R. Spinler, Cory Alvey
  • Compositions and methods for selective phagocytosis of human cancer cells
    Patent number: 10946042
    Abstract: The present invention relates to compositions and methods that provide novel therapies in cancer. The invention includes a phagocytic cell modified with a repressor of signal regulatory protein-alpha (SIRP?) and bound to a targeting antibody to enhance phagocytic activity of the phagocytic cell toward tumor tissue. Methods of enhancing phagocytic activity and treating a tumor are also included.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: March 16, 2021
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Dennis E. Discher, Kyle R. Spinler, Cory Alvey
  • COMPOSITIONS AND METHODS FOR SELECTIVE PHAGOCYTOSIS OF HUMAN CANCER CELLS
    Publication number: 20170151282
    Abstract: The present invention relates to compositions and methods that provide novel therapies in cancer. The invention includes a phagocytic cell modified with a repressor of signal regulatory protein-alpha (SIRP?) and bound to a targeting antibody to enhance phagocytic activity of the phagocytic cell toward tumor tissue. Methods of enhancing phagocytic activity and treating a tumor are also included.
    Type: Application
    Filed: December 1, 2016
    Publication date: June 1, 2017
    Inventors: Dennis E. Discher, Kyle R. Spinler, Cory Alvey