Patents by Inventor Cory Johannessen

Cory Johannessen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR STUDYING CELL EVOLUTION
    Publication number: 20230083163
    Abstract: The subject matter disclosed herein is generally directed to methods and compositions for tagging cells of interest, tracking evolution of the tagged cells, and recovering the original tagged cells for further study. Specifically, cells are tagged with a DNA construct encoding a barcode sequence comprising a guide sequence. Barcoded cells can then be recovered using a reporter construct having CRISPR target sequences specific for the cell having a barcode of interest.
    Type: Application
    Filed: November 22, 2022
    Publication date: March 16, 2023
    Inventors: Pratiti Bandopadhayay, Rameen Beroukhim, Paul Blainey, David Feldman, Cory Johannessen, Funien Tsai
  • Methods and compositions for studying cell evolution
    Patent number: 11547614
    Abstract: The subject matter disclosed herein is generally directed to methods and compositions for tagging cells of interest, tracking evolution of the tagged cells, and recovering the original tagged cells for further study. Specifically, cells are tagged with a DNA construct encoding a barcode sequence comprising a guide sequence. Barcoded cells can then be recovered using a reporter construct having CRISPR target sequences specific for the cell having a barcode of interest.
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: January 10, 2023
    Assignees: THE BROAD INSTITUTE, INC., DANA-FARBER CANCER INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Pratiti Bandopadhayay, Rameen Beroukhim, Paul Blainey, David Feldman, Cory Johannessen, Funien Tsai
  • METHODS AND COMPOSITIONS FOR STUDYING CELL EVOLUTION
    Publication number: 20210180058
    Abstract: The subject matter disclosed herein is generally directed to methods and compositions for tagging cells of interest, tracking evolution of the tagged cells, and recovering the original tagged cells for further study. Specifically, cells are tagged with a DNA construct encoding a barcode sequence comprising a guide sequence. Barcoded cells can then be recovered using a reporter construct having CRISPR target sequences specific for the cell having a barcode of interest.
    Type: Application
    Filed: October 31, 2018
    Publication date: June 17, 2021
    Inventors: Pratiti BANDOPADHAYAY, Rameen BEROUKHIM, Paul BLAINEY, David FELDMAN, Cory JOHANNESSEN, Funien TSAI
  • SYNERGISTIC DRUG COMBINATIONS PREDICTED FROM GENOMIC FEATURES AND SINGLE-AGENT RESPONSE PROFILES
    Publication number: 20210069230
    Abstract: The present disclosure relates to discovery of specific synergistic drug combinations and mechanisms of drug resistance. Compositions involving newly-identified drug combinations as well as diagnostic and therapeutic methods related to such discoveries are provided.
    Type: Application
    Filed: April 12, 2019
    Publication date: March 11, 2021
    Applicant: THE BROAD INSTITUTE, INC.
    Inventors: Matthew Rees, Cory Johannessen