Abstract: A method and apparatus for the application of an electrical signal to neural tissue and other target tissue in the living body.

Abstract: Dimercaptan terminated polythioether polymers are disclosed, as are methods for making and using the same.

Abstract: A community-based system and method for providing automatic discounting of a purchase is described. A database containing a plurality of items for purchase and a plurality of discounts associated with the items is provided. A search query is received from a user using a networked device, and items responsive to the search query are transmitted to the device for display. The device is then usable to select one or more displayed items. Corresponding discounts are automatically associated with the selected items, and when purchase of the item is completed, the associated discounts are applied in a paperless manner. Concurrent with the discount feature, users are permitted to create customizable user accounts, through which favorite items and groupings of items can be uploaded, flagged, stored, and shared with other users. User accounts are usable for tracking of demographic information, communication with other users, and providing automatic notifications based on user-selected preferences.

Abstract: A new family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridize to oligonucleotide probes having defined sequences, processes for producing polypeptides of the LIR family, and antagonistic antibodies to LIR family members. LIR family members can be used to treat autoimmune diseases and disease states associated with suppressed immune function.

Abstract: The invention is directed to purified and isolated novel ULBP polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and the uses of the above. ULBP polypeptide can be found on the surface of human B cell lymphomas. Mammalian forms of ULBP polypeptide in isolated or purified forms are provided. In addition, isolated nucleic acids encoding ULBP polypeptides and expression vectors comprising a cDNA encoding ULBP polypeptides are provided. The ULBP polypeptides can be isolated or synthesized and used to prepare antibodies, and in particular monoclonal antibodies, against the polypeptides. The antibodies, in turn, are useful for detecting the presence of ULBP polypeptides in human cell samples, which can be correlated with the existence of a malignant condition in a patient.

Abstract: A polymer blend having at least one polysulfide component and at least one polythioether component is disclosed. The polymer blend offers numerous advantages, including the ability to compatibilize formulations based on either polysulfide chemistry or polythioether chemistry alone. Compositions comprising the polymer blend, particularly sealant formulations for use in aerospace applications, are also disclosed, as are multilayer sealant assemblies and methods for repairing the same.

Abstract: A multi-layer aircraft adhesive composition is provided having a first layer prepared from a first composition having a Part A and a Part B. Part A contains a plasticizer, a crosslinking agent, and an adhesion promoter. Part B contains a moisture resister and an abrasion resister. The composition has a second layer formed over at least a portion of the first layer. The second layer is prepared from a second composition having a Part C and a Part D. Part C contains at least one polythiol functional polymer, at least one epoxy resin, at least one sulfur containing material that is different from the at least one polythiol functional polymer, at least one plasticizer, and at least one filler. Part D contains at least one plasticizer, at least one of manganese dioxide or lead oxide, and at least one alkaline agent.

Abstract: Rigid polyurethane foams are made using a polyol component that includes toluene diamine-initiated polyols containing specified levels of oxyethylene groups. Foams made from these polyols have low k-factors and excellent demold expansion values.

Abstract: Dimercaptan terminated polythioether polymers are disclosed, as are methods for making and using the same.

Abstract: A polymer blend having at least one polysulfide component and at least one polythioether component is disclosed. The polymer blend offers numerous advantages, including the ability to compatibilize formulations based on either polysulfide chemistry or polythioether chemistry alone. Compositions comprising the polymer blend, particularly sealant formulations for use in aerospace applications, are also disclosed, as are multilayer sealant assemblies and methods for repairing the same.

Abstract: A NMR (nuclear magnetic resonance) transmit/receive switch according to some embodiments of a nuclear magnetic resonance apparatus includes receive-path and/or transmit-path superconductors, which are selectively quenched to switch the connection of an NMR radio-frequency coil between transmit and receive circuits. In the transmit state, the transmit-path superconductor is in a superconducting state while the receive-path superconductor is quenched, to isolate a receive-path amplifier from the relatively higher powers of the NMR pulses applied to the sample by the transmit circuit. In the receive state, the receive-path superconductor is in a superconducting state while the transmit-path superconductor is quenched. A DC power source is used to supply supercritical current to the superconductors to quench the superconductors.

Abstract: The invention is directed to purified and isolated novel ULBP polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and the uses of the above. ULBP polypeptide can be found on the surface of human B cell lymphomas. Mammalian forms of ULBP polypeptide in isolated or purified forms are provided. In addition, isolated nucleic acids encoding ULBP polypeptides and expression vectors comprising a cDNA encoding ULBP polypeptides are provided. The ULBP polypeptides can be isolated or synthesized and used to prepare antibodies, and in particular monoclonal antibodies, against the polypeptides. The antibodies, in turn, are useful for detecting the presence of ULBP polypeptides in human cell samples, which can be correlated with the existence of a malignant condition in a patient.

Abstract: A polymer blend having at least one polysulfide component and at least one polythioether component is disclosed. The polymer blend offers numerous advantages, including the ability to compatibilize formulations based on either polysulfide chemistry or polythioether chemistry alone. Compositions comprising the polymer blend, particularly sealant formulations for use in aerospace applications, are also disclosed, as are multilayer sealant assemblies and methods for repairing the same.

Abstract: ULBP4, a novel member of the ULBP family has been isolated and characterized. ULBP4 is a useful activator of immune effector cells, particularly of NK cells.

Abstract: A polymer blend having at least one polysulfide component and at least one polythioether component is disclosed. The polymer blend offers numerous advantages, including the ability to compatibilize formulations based on either polysulfide chemistry or polythioether chemistry alone. Compositions comprising the polymer blend, particularly sealant formulations for use in aerospace applications, are also disclosed, as are multilayer sealant assemblies and methods for repairing the same.

Abstract: A new family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridize to oligonucleotide probes having defined sequences, processes for producing polypeptides of the LIR family, and antagonistic antibodies to LIR family members. LIR family members can be used to treat autoimmune diseases and disease states associated with suppressed immune function.

Abstract: Preformed compositions in shaped form comprising polymer blends, and the use of these preformed compositions in shaped form to seal apertures are disclosed. In certain embodiments, the preformed compositions are electrically conductive and are capable of shielding EMI/RFI radiation. The polymer blend includes a polysulfide component and a polythioether component.

Abstract: Mammalian Interleukin-4 receptor proteins, DNAs and expression vectors encoding mammalian IL-4 receptors, and processes for producing mammalian IL-4 receptors as products of cell culture, are disclosed. A method for suppressing an IL-4-dependent immune or inflammatory response in a mammal, including a human, by administering an effective amount of soluble IL-4 receptor (sIL-4R) and a suitable diluent or carrier.

Abstract: ULBP4, a novel member of the ULBP family has been isolated and characterized. ULBP4 is a useful activator of immune effector cells, particularly of NK cells.

Abstract: A method and apparatus for altering a function of neural tissue in a patient. An electromagnetic signal is applied to the neural tissue through an electrode. The electromagnetic signal has a frequency component above the physiological stimulation frequency range and an intensity sufficient to product an alteration of the neural tissue, the alteration causing the patient to experience a reduction in pain, and a waveform that prevents lethal temperature elecation of the neural tissue during application of the electromagnetic signal to the neural tissue.