Patents by Inventor Cosmin Deciu

Cosmin Deciu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and processes for non-invasive assessment of genetic variations
    Patent number: 10504613
    Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: December 10, 2019
    Assignee: Sequenom, Inc.
    Inventors: Sung K. Kim, Cosmin Deciu
  • Methods and processes for non-invasive assessment of genetic variations
    Patent number: 10497462
    Abstract: Provided herein are methods, processes, systems and apparatuses for non-invasive assessment of a chromosome aneuploidy in a fetus according to a comparison of ratios of counts of sequence reads mapped to certain chromosomes. Also provided herein are methods, processes, systems and apparatuses for non-invasive assessment of a copy number variation in a fetus.
    Type: Grant
    Filed: July 2, 2013
    Date of Patent: December 3, 2019
    Assignee: Sequenom, Inc.
    Inventors: Cosmin Deciu, Zeljko Dzakula
  • Methods and processes for non-invasive assessment of genetic variations
    Patent number: 10497461
    Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: December 3, 2019
    Assignee: Sequenom, Inc.
    Inventors: Zeljko Dzakula, Amin R. Mazloom, Cosmin Deciu, Huiquan Wang
  • Methods and processes for non-invasive assessment of genetic variations
    Patent number: 10482994
    Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: November 19, 2019
    Assignee: Sequenom, Inc.
    Inventors: Cosmin Deciu, Zeljko Dzakula, Amin Mazloom
  • METHODS AND PROCESSES FOR NON-INVASIVE ASSESSMENT OF GENETIC VARIATIONS
    Publication number: 20190309351
    Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.
    Type: Application
    Filed: April 26, 2019
    Publication date: October 10, 2019
    Inventors: Cosmin DECIU, Zeljko Jovan DZAKULA, Mathias EHRICH, Sung Kyun KIM
  • Methods and processes for non-invasive assessment of genetic variations
    Patent number: 10424394
    Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: September 24, 2019
    Assignee: Sequenom, Inc.
    Inventors: Cosmin Deciu, Zeljko Dzakula
  • Methods and Processes for Non-Invasive Assessment of Genetic Variations
    Publication number: 20190276874
    Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.
    Type: Application
    Filed: December 10, 2018
    Publication date: September 12, 2019
    Inventors: Cosmin Deciu, Zeljko Dzakula, John Allen Tynan, Grant Hogg
  • Methods and processes for non-invasive assessment of genetic variations
    Patent number: 10323268
    Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: June 18, 2019
    Assignee: Sequenom, Inc.
    Inventors: Cosmin Deciu, Zeljko Jovan Dzakula, Mathias Ehrich, Sung Kyun Kim
  • Methods and processes for non-invasive assessment of genetic variations
    Patent number: 10196681
    Abstract: Provided herein are methods, processes and apparatuses for determining the fraction of fetal nucleic acid in a test sample derived from a pregnant female with improved accuracy and/or precision. Also, provided herein are methods, processes and apparatuses for determining the presence or absence of a genetic variation in a fetus with improved accuracy and/or precision. Certain methods include using fetal fraction measurements for the determination of a fetal genetic variation.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: February 5, 2019
    Assignee: Sequenom, Inc.
    Inventors: Cosmin Deciu, Zeljko Dzakula, John Allen Tynan, Grant Hogg
  • METHODS AND PROCESSES FOR NON-INVASIVE ASSESSMENT OF GENETIC VARIATIONS
    Publication number: 20190005188
    Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.
    Type: Application
    Filed: April 23, 2018
    Publication date: January 3, 2019
    Inventors: COSMIN DECIU, Zeljko DZAKULA, Mathias EHRICH, Taylor Jacob JENSEN
  • METHODS AND PROCESSES FOR NON-INVASIVE ASSESSMENT OF GENETIC VARIATIONS
    Publication number: 20180327844
    Abstract: Provided herein are methods, processes, systems, machines and apparatuses for non-invasive assessment of genetic variations.
    Type: Application
    Filed: November 8, 2016
    Publication date: November 15, 2018
    Inventors: COSMIN DECIU, SUNG KIM, CHEN ZHAO, GREGORY HANNUM
  • Chromosome Representation Determinations
    Publication number: 20180282801
    Abstract: Technology described herein pertains in part to diagnostic tests that make use of sequence reads generated by a sequencing process. In some embodiments, a component used to generate a chromosome representation can be based on counts of sequence reads not aligned to a reference genome.
    Type: Application
    Filed: April 27, 2018
    Publication date: October 4, 2018
    Applicant: Sequenom, Inc.
    Inventors: Chen Zhao, Cosmin Deciu
  • PROCESSES AND KITS FOR IDENTIFYING ANEUPLOIDY
    Publication number: 20180237825
    Abstract: Provided are methods for identifying the presence or absence of a chromosome abnormality by which a cell-free sample nucleic acid from a subject is analyzed. In certain embodiments, provided are methods for identifying the presence or absence of a fetal chromosome abnormality in a nucleic acid from cell-free maternal blood.
    Type: Application
    Filed: February 8, 2018
    Publication date: August 23, 2018
    Inventors: Mathias EHRICH, Guy Del MISTRO, Cosmin DECIU, Yong Qing CHEN, Ron Michael McCULLOUGH, Roger Chan TIM
  • METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACID
    Publication number: 20180230532
    Abstract: Technology provided herein relates in part to methods, processes, compositions and apparatuses for analyzing nucleic acid.
    Type: Application
    Filed: February 12, 2018
    Publication date: August 16, 2018
    Inventors: Sung K. KIM, Cosmin DECIU
  • Reducing sequence read count error in assessment of complex genetic variations
    Patent number: 9984198
    Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: May 29, 2018
    Assignee: SEQUENOM, INC.
    Inventors: Cosmin Deciu, Zeljko Dzakula, Mathias Ehrich, Taylor Jacob Jensen
  • Processes and kits for identifying aneuploidy
    Patent number: 9926593
    Abstract: Provided are methods for identifying the presence or absence of a chromosome abnormality by which a cell-free sample nucleic acid from a subject is analyzed. In certain embodiments, provided are methods for identifying the presence or absence of a fetal chromosome abnormality in a nucleic acid from cell-free maternal blood.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: March 27, 2018
    Assignee: SEQUENOM, INC.
    Inventors: Mathias Ehrich, Guy Del Mistro, Cosmin Deciu, Yong Qing Chen, Ron Michael McCullough, Roger Chan Tim
  • Methods and compositions for analyzing nucleic acid
    Patent number: 9920361
    Abstract: Technology provided herein relates in part to methods, processes, compositions and apparatuses for analyzing nucleic acid.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: March 20, 2018
    Assignee: SEQUENOM, INC.
    Inventors: Sung K. Kim, Cosmin Deciu
  • Genetic Copy Number Alteration Classifications
    Publication number: 20180032671
    Abstract: Technology provided herein relates in part to non-invasive classification of one or more genetic copy number alterations (CNAs) for a test sample. Certain methods include sampling a quantification of sequence reads from parts of a genome, generating a confidence determination, and using the confidence determination to enhance classification. Technology provided herein is useful for classifying a genetic CNA for a sample as part of non-invasive pre-natal (NIPT) testing and oncology testing, for example.
    Type: Application
    Filed: July 27, 2017
    Publication date: February 1, 2018
    Inventors: Amin Mazloom, Cosmin Deciu, Chen Zhao, Tong Liu, Yijin Wu
  • METHODS AND PROCESSES FOR NON INVASIVE ASSESSMENT OF A GENETIC VARIATION
    Publication number: 20180032665
    Abstract: Provided in part herein are methods and processes that can be used for non-invasive assessment of a genetic variation which can lead to diagnosis of a particular medical condition or conditions. Such methods and processes can, for example, identify dissimiliarities or similarities for one or more features between a subject data set and a reference data set, generate a multidimensional matrix, reduce the matrix into a representation and classify the representation into one or more groups. Methods and processes described herein are applicable to data in biotechnology and other fields.
    Type: Application
    Filed: July 11, 2017
    Publication date: February 1, 2018
    Inventors: Lin TANG, Cosmin DECIU
  • METHODS AND PROCESSES FOR NON-INVASIVE ASSESSMENT OF GENETIC VARIATIONS
    Publication number: 20180030528
    Abstract: Technology provided herein relates in part to methods, processes and apparatuses for non-invasive assessment of genetic variations.
    Type: Application
    Filed: July 11, 2017
    Publication date: February 1, 2018
    Inventors: Dirk Johannes VAN DEN BOOM, Charles R. CANTOR, Sung Kyun KIM, Zeljko DZAKULA, Cosmin DECIU