Patents by Inventor Cotïc Kalinski

Cotïc Kalinski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrahydro-isoquinolin-1-ones for the treatment of cancer
    Patent number: 8163744
    Abstract: The present invention provides a compound selected from compounds of formula I as ligand binding to the HDM2 protein, inducing apoptosis and inhibiting proliferation, and having therapeutic utility in cancer therapy. Compounds of formula (I) can be used as therapeutics for treating stroke, myocardial infarction, ischemia, multi-organ failure, spinal cord injury, Alzheimer's Disease, injury from ischemic events, heart valvular degenerative disease Moreover, compounds of formula (I) can be used to decrease the side effects from cytotoxic cancer agents and to treat viral infections.
    Type: Grant
    Filed: March 17, 2006
    Date of Patent: April 24, 2012
    Assignee: NexusPharma, Inc.
    Inventors: Lutz Weber, Vladimir Khazak, Günther F Ross, Cotïc Kalinski, Christoph Burdack
  • TETRAHYDRO-ISOQUINOLIN-1-ONES FOR THE TREATMENT OF CANCER
    Publication number: 20090068144
    Abstract: The present invention provides a compound selected from compounds of formula I as ligand binding to the HDM2 protein, inducing apoptosis and inhibiting proliferation, and having therapeutic utility in cancer therapy. Compounds of formula (I) can be used as therapeutics for treating stroke, myocardial infarction, ischemia, multi-organ failure, spinal cord injury, Alzheimer's Disease, injury from ischemic events, heart valvular degenerative disease Moreover, compounds of formula (I) can be used to decrease the side effects from cytotoxic cancer agents and to treat viral infections.
    Type: Application
    Filed: March 17, 2006
    Publication date: March 12, 2009
    Inventors: Lutz Weber, Vladimir Khazak, Gunther Ross, Cotic Kalinski, Chritoph Burdack