Patents by Inventor Counde O'Yang

Counde O'Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE
    Publication number: 20230312524
    Abstract: The present disclosure relates generally to chemical compounds and, in some embodiments, to ?1A-adrenergic receptor agonists and uses of such agonists in the treatment of diseases associated with an adrenergic receptor. Disclosed herein is a compound according to Formula (I) or an optically pure stereoisomer, pharmaceutically acceptable salt, solvate, or prodrug thereof.
    Type: Application
    Filed: August 26, 2021
    Publication date: October 5, 2023
    Inventors: David Scott Carter, Counde O'Yang, Anthony P. Ford, Wei Chen
  • Pyrrolopyrazine kinase inhibitors
    Patent number: 8658646
    Abstract: The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Grant
    Filed: August 31, 2012
    Date of Patent: February 25, 2014
    Assignee: Hoffmann-LaRoche Inc.
    Inventors: Shaoqing Chen, Javier de Vicente Fidalgo, Matthew Michael Hamilton, Johannes Cornelius Hermann, Joshua Kennedy-Smith, Hongju Li, Allen John Lovey, Matthew C. Lucas, Kin-Chun Thomas Luk, Stephen M. Lynch, Counde O'yang, Fernando Padilla, Ryan Craig Schoenfeld, Achyutharao Sidduri, Michael Soth, Ce Wang, Peter Michael Wovkulich, Xiaohu Zhang
  • PYRROLOPYRAZINE KINASE INHIBITORS
    Publication number: 20130059834
    Abstract: The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Application
    Filed: August 31, 2012
    Publication date: March 7, 2013
    Inventors: Shaoqing Chen, Javier de Vicente Fidalgo, Matthew Michael Hamilton, Johannes Cornelius Hermann, Joshua Kennedy-Smith, Hongju Li, Allen John Lovey, Matthew C. Lucas, Kin-Chun Thomas Luk, Stephen M. Lynch, Counde O'yang, Fernando Padilla, Ryan Craig Schoenfeld, Achyutharao Sidduri, Michael Soth, Ce Wang, Peter Michael Wovkulich, Xiaohu Zhang
  • IMIDAZOLINYLMETHYL ARYL SULFONAMIDE
    Publication number: 20110237639
    Abstract: This invention relates to an alpha-1 A receptor partial agonist, which is represented by Formula I: and pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing formula I, methods for their use as therapeutic agents, and methods of preparation thereof.
    Type: Application
    Filed: June 3, 2011
    Publication date: September 29, 2011
    Inventors: Counde O'Yang, Dennis Mitsugu Yasuda
  • IMIDAZOLINYLMETHYL ARYL SULFONAMIDE
    Publication number: 20110230535
    Abstract: This invention relates to an alpha-1A receptor partial agonist, which is represented by Formula I: and pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing formula I, methods for their use as therapeutic agents, and methods of preparation thereof.
    Type: Application
    Filed: June 3, 2011
    Publication date: September 22, 2011
    Inventors: Counde O'Yang, Robert Greenhouse
  • Non-nucleoside reverse transcriptase inhibitors
    Patent number: 7947709
    Abstract: Compounds of formula I, wherein R1, R2, R3, X and Ar, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula I useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: May 24, 2011
    Assignee: Roche Palo Alto LLC
    Inventors: Todd Richard Elworthy, Joan Heather Hogg, Joshua Kennedy-Smith, Counde O'Yang, Mark Smith, Zachary Kevin Sweeney, Jeffrey Wu
  • Propionamide compounds as antiinflammatory agents
    Patent number: 7868031
    Abstract: The present invention relates to propionamide compounds of formula I for use as antiinflammatory agents: wherein R1, R2 and R3 are as defined herein and pharmaceutically acceptable salts thereof. The invention also relates to methods of using the compounds of formula I and pharmaceutical compositions comprising the compounds of formula I.
    Type: Grant
    Filed: December 8, 2006
    Date of Patent: January 11, 2011
    Assignee: Roche Palo Alto LLC
    Inventors: Leyi Gong, Counde O'Yang, Yun-chou Tan
  • Imidazolinylmethyl aryl sulfonamide
    Patent number: 7799816
    Abstract: This invention relates to an alpha-1 A receptor partial agonist, which is represented by Formula I: and pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing formula I, methods for their use as therapeutic agents, and methods of preparation thereof.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: September 21, 2010
    Assignee: Roche Palo Alto LLC
    Inventors: Counde O'Yang, Robert Greenhouse
  • Indole and benzofuran 2-carboxamide derivatives and uses thereof
    Patent number: 7741326
    Abstract: Compounds of formula I or formula II: or pharmaceutically acceptable salts thereof, wherein m, n, p, Ar R1, R2, R4, and R5 are as defined herein. The invention also provides methods for preparing, compositions comprising, and methods for using compounds.
    Type: Grant
    Filed: November 8, 2007
    Date of Patent: June 22, 2010
    Assignee: Roche Palo Alto LLC
    Inventors: Joe Timothy Bamberg, Counde O'Yang, Meng Sui, Shu-Hai Zhao
  • IMIDAZOLINYLMETHYL ARYL SULFONAMIDE
    Publication number: 20090197933
    Abstract: This invention relates to an alpha-1 A receptor partial agonist, which is represented by Formula I: and pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing formula I, methods for their use as therapeutic agents, and methods of preparation thereof.
    Type: Application
    Filed: February 4, 2009
    Publication date: August 6, 2009
    Inventors: Counde O'Yang, Dennis Mitsugu Yasuda
  • IMIDAZOLINYLMETHY ARYL SULFONAMIDE
    Publication number: 20090197931
    Abstract: This invention relates to an alpha-1 A receptor partial agonist, which is represented by Formula I: and pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing formula I, methods for their use as therapeutic agents, and methods of preparation thereof.
    Type: Application
    Filed: February 4, 2009
    Publication date: August 6, 2009
    Inventors: Counde O'Yang, Robert Greenhouse
  • IMIDAZOLINYLMETHYL ARYL SULFONAMIDE
    Publication number: 20090197932
    Abstract: This invention relates to an alpha-1A receptor partial agonist, which is represented by Formula I: and pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing formula I, methods for their use as therapeutic agents, and methods of preparation thereof.
    Type: Application
    Filed: February 4, 2009
    Publication date: August 6, 2009
    Inventors: Counde O'Yang, Dennis Mitsugu Yasuda
  • IMIDAZOLINYLMETHYL ARYL SULFONAMIDE
    Publication number: 20090197934
    Abstract: This invention relates to an alpha-1A receptor partial agonist, which is represented by Formula I: and pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing formula I, methods for their use as therapeutic agents, and methods of preparation thereof.
    Type: Application
    Filed: February 4, 2009
    Publication date: August 6, 2009
    Inventors: Counde O'Yang, Robert Greenhouse
  • Substituted pyrazolo{3,4-D}pyrimidines as p38 map kinase inhibitors
    Patent number: 7566708
    Abstract: Compounds effective as p38 MAP kinase inhibitors, methods of making the compounds, and methods of using the compounds for treatment of p38 MAP kinase-mediated diseases.
    Type: Grant
    Filed: August 23, 2006
    Date of Patent: July 28, 2009
    Assignee: Roche Palo Alto LLC
    Inventors: Nidhi Arora, Roland Joseph Billedeau, Nolan James Dewdney, Tobias Gabriel, David Michael Goldstein, Counde O'Yang, Michael Soth, Teresa Alejandra Trejo-Martin
  • Non-Nucleoside reverse transcriptase inhibitors
    Publication number: 20090012034
    Abstract: Compounds of formula I, wherein R1, R2, R3, X and Ar, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula I useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC.
    Type: Application
    Filed: June 20, 2008
    Publication date: January 8, 2009
    Inventors: Todd Richard Elworthy, Joan Heather Hogg, Joshua Kennedy-Smith, Counde O'Yang, Mark Smith, Zachary Kevin Sweeney, Jeffrey Wu
  • Substituted pyrazolo[3,4-d]pyrimadines and methods of using the same
    Patent number: 7435731
    Abstract: Compounds of the formula Ia or Ib: wherein A, B, X, Y, Z, W, k, R1, R2, R3, R4 and R5 are those defined herein, and compositions comprising the same. The present invention also provides methods for preparing compounds of formula I and using the same in treating p38 mediated disorders in a subject.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: October 14, 2008
    Assignee: Roche Palo Alto LLC
    Inventors: Nidhi Arora, Roland Joseph Billedeau, Nolan James Dewdney, Tobias Gabriel, David Michael Goldstein, Counde O'Yang, Michael Soth
  • Heterocyclic GABAsubtype selective receptor modulators
    Patent number: 7432283
    Abstract: This invention relates to a method for modulating ?2 subtype GABAA receptors with heterocyclic compounds of formula I, and salts, solvates and prodrugs thereof. The invention further relates to novel heteocyclic compounds and pharmaceutical compositions containing said compounds.
    Type: Grant
    Filed: February 18, 2005
    Date of Patent: October 7, 2008
    Assignee: Roche Palo Alto LLC
    Inventors: David Garrett Loughhead, Sanja Novakovic, Counde O'Yang, David George Putman, Michael Soth
  • Pyrazolyl and imidazolyl pyrimidines as CRF antagonists
    Patent number: 7414059
    Abstract: Compounds of the formula (I): and pharmaceutically acceptable salts or prodrugs thereof, wherein X, Y, Z and R1 are as defined herein. The invention also provides methods for preparing, compositions comprising, and methods for using compounds of formula I.
    Type: Grant
    Filed: November 24, 2004
    Date of Patent: August 19, 2008
    Assignee: Roche Palo Alto LLC
    Inventors: Alam Jahangir, Counde O'Yang
  • Imidazolinylmethyl aralkylsulfonamides
    Patent number: 7407980
    Abstract: Compounds of the Formula: where R1-R6 are those defined herein and methods for producing the same. Also provided are pharmaceutical compositions comprising a Compound of Formula I and methods for their use as therapeutic agents.
    Type: Grant
    Filed: April 13, 2004
    Date of Patent: August 5, 2008
    Assignee: Roche Palo Alto LLC
    Inventors: Michael Patrick Dillon, Clara Jeou Jen Lin, Counde O'Yang, Xiaoming Zhang
  • Indole and benzofuran 2-carboxamide derivatives and uses thereof
    Publication number: 20080146587
    Abstract: Compounds of formula I or formula II: or pharmaceutically acceptable salts thereof, wherein m, n, p, Ar R1, R2, R4, and R5 are as defined herein. The invention also provides methods for preparing, compositions comprising, and methods for using compounds.
    Type: Application
    Filed: November 8, 2007
    Publication date: June 19, 2008
    Inventors: Joe Timothy Bamberg, Counde O'Yang, Meng Sui, Shu-Hai Zhao