Patents by Inventor Courtney A. Cullis

Courtney A. Cullis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROARYLS AND USES THEREOF
    Publication number: 20120142732
    Abstract: This invention provides compounds of formula IA or IB: wherein HY, R1, R2, and G1, are as described in the specification. The compounds are inhibitors of VPS34 and/or PI3K and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
    Type: Application
    Filed: August 10, 2011
    Publication date: June 7, 2012
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Courtney A. Cullis, Krista E. Granger, Jianping Guo, Masaaki Hirose, Gang Li, Miho Mizutani, Tricia J. Vos
  • HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF E1 ACTIVATING ENZYMES
    Publication number: 20120071482
    Abstract: This invention relates to compounds that inhibit E1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.
    Type: Application
    Filed: August 24, 2011
    Publication date: March 22, 2012
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Christopher F. Claiborne, Stephen Critchley, Courtney Cullis, Steven P. Langston, Hirotake Mizutani, Edward J. Olhava, Stephane Peluso, Irache Visiers, Stepan Vyskocil, Gabriel S. Weatherhead
  • Heteroaryl compounds useful as inhibitors of E1 activating enzymes
    Patent number: 8008307
    Abstract: This invention relates to compounds that inhibit E1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: August 30, 2011
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Christopher F. Claiborne, Stephen Critchley, Courtney Cullis, Steven P. Langston, Hirotake Mizutani, Edward J. Olhava, Stephane Peluso, Irache Visiers, Stepan Vyskocil, Gabriel S. Weatherhead
  • Lactam compounds useful as protein kinase inhibitors
    Patent number: 7935694
    Abstract: The present invention provides novel compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Grant
    Filed: September 4, 2008
    Date of Patent: May 3, 2011
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Christopher Blackburn, Christopher F. Claiborne, Courtney A. Cullis, Natalie A. Dales, Michael Patane, Matthew Stirling, Omar Stradella, Gabriel S. Weatherhead
  • LACTAM COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS
    Publication number: 20110039820
    Abstract: The present invention provides novel compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: October 13, 2010
    Publication date: February 17, 2011
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Christopher Blackburn, Christopher F. Claiborne, Courtney A. Cullis, Natalie A. Dales, Michael Patane, Matthew Stirling, Omar Stradella, Gabriel S. Weatherhead
  • Lactam compounds useful as protein kinase inhibitors
    Publication number: 20090105213
    Abstract: The present invention provides novel compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: September 4, 2008
    Publication date: April 23, 2009
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Christopher Blackburn, Christopher F. Claiborne, Courtney A. Cullis, Natalie A. Dales, Michael Patane, Matthew Stirling, Omar Stradella, Gabriel S. Weatherhead
  • Lactam compounds useful as protein kinase inhibitors
    Patent number: 7459448
    Abstract: The present invention provides novel compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Grant
    Filed: October 3, 2005
    Date of Patent: December 2, 2008
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Christopher Blackburn, Christopher F. Claiborne, Courtney A. Cullis, Natalie A. Dales, Michael Patane, Matthew Stirling, Omar Stradella, Gabriel S. Weatherhead
  • Heteroaryl compounds useful as inhibitors of E1 activating enzymes
    Publication number: 20080051404
    Abstract: This invention relates to compounds that inhibit E1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.
    Type: Application
    Filed: August 6, 2007
    Publication date: February 28, 2008
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Christopher Claiborne, Stephen Critchley, Courtney Cullis, Steven Langston, Hiro Mizutani, Edward Olhava, Stephane Peluso, Irache Visiers, Stepan Vyskocil, Gabriel Weatherhead
  • Lactam compounds useful as protein kinase inhibitors
    Publication number: 20060100194
    Abstract: The present invention provides novel compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: October 3, 2005
    Publication date: May 11, 2006
    Inventors: Christopher Blackburn, Christopher Claiborne, Courtney Cullis, Natalie Dales, Michael Patane, Matthew Stirling, Omar Stradella, Gabriel Weatherhead
  • Chk-1 inhibitors
    Publication number: 20060035920
    Abstract: Disclosed are novel inhibitors of Chk-1 and methods of using the same for therapy.
    Type: Application
    Filed: May 27, 2005
    Publication date: February 16, 2006
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Robert Boyle, Hassan Imogai, Michael Cherry, Alfred Humphries, Eva Navarro, David Owen, Natalie Dales, Matthew LaMarche, Courtney Cullis, Alexandra Gould, Paul Greenspan
  • Chk-1 inhibitors
    Publication number: 20050245563
    Abstract: Disclosed are novel inhibitors of Chk-1 and methods of using the same for therapy.
    Type: Application
    Filed: May 28, 2004
    Publication date: November 3, 2005
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Robert Boyle, Hassan Imogai, Michael Cherry, Alfred Humphries, Eva Navarro, David Owen, Natalie Dales, Matthew LaMarche, Courtney Cullis, Alexandra Gould
  • Antagonists of melanin concentrating hormone receptor
    Patent number: 6921821
    Abstract: This invention provides compounds that are antagonists of melanin concentrating hormone receptor-1 (MCH-R1). The compounds are represented by formula I: where m is zero or one, n is zero to two, Y is oxygen or —N(R9)—, R1, R2, R3, R4, R5, R9 and Ring A are defined in the specification. Coumarin and quinolone compounds where R1 and R2 together form a fused benzo ring are preferred. The invention also provides compounds of formula VI where the coumarin moiety is replaced by a quinazolinone ring. The compounds are useful for treating MCH-R1-related disorders, particularly overweight conditions including obesity.
    Type: Grant
    Filed: June 11, 2003
    Date of Patent: July 26, 2005
    Assignee: Abbott Laboratories
    Inventors: Christopher Blackburn, Su-Jen Lai, Jennifer L. Che, Martin P. Maguire, Michael A. Patane, Matthew J. LaMarche, Courtney A. Cullis, James Brown, Anil Vasudevan, Jennifer C. Freeman, Mathew M. Mulhern, John K. Lynch, Ju Gao, Dariusz Wodka, Andrew J. Souers, Rajesh Iyengar, Mary Katherin Verzal, Philip R. Kym
  • Antagonists of melanin concentrating hormone receptor
    Publication number: 20040106645
    Abstract: This invention provides compounds that are antagonists of melanin concentrating hormone receptor-1 (MCH-R1).
    Type: Application
    Filed: June 11, 2003
    Publication date: June 3, 2004
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Christopher Blackburn, Su-Jen Lai, Jennifer L. Che, Martin P. Maguire, Michael A. Patane, Matthew J. LaMarche, Courtney A. Cullis, James Brown, Anil Vasudevan, Jennifer C. Freeman, Mathew M. Mulhern, John K. Lynch, Ju Gao, Dariusz Wodka, Andrew J. Souers, Rajesh Iyengar, Mary Katherin Verzal, Philip R. Kym