Abstract: The present invention is directed to a non-incinerating medical waste treatment device and methods of use. The device comprising two to four thermal chambers with total independent operation and controls. The desktop mountable device contains electronic, electromechanical, and made-up mechanical assemblies. The intended application of the device and method is for sterilizing medical waste such as bacterial and viral biological contaminated red bag and/or sharps in order to facilitate safe handling and disposal.