Abstract: The present invention relates to medical gloves, as well as gloves that are used to protect a person's hand from harmful substances. According to certain embodiments of the present invention, protective gloves are provided that comprise four fingers and a thumb portion, wherein the thumb portion comprises a unique mark that visually differentiates the thumb portion from the four fingers. Alternatively, according to other embodiments of the present invention, the protective gloves comprise a small-finger portion, three additional fingers and a thumb portion, wherein the small-finger portion comprises a unique mark that visually differentiates the small-finger portion from the three additional fingers and the thumb portion.