Patents by Inventor Courtney M. Starks

Courtney M. Starks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phenethyldihydrobenzodioxolones and methods of use
    Patent number: 9562031
    Abstract: The present invention generally relates to phenethyldihydrobenzodioxolone compounds and compositions useful for reducing or inhibiting tumor growth. It also relates to methods of use and the preparation of phenethyldihydrobenzodioxolone compounds.
    Type: Grant
    Filed: September 12, 2015
    Date of Patent: February 7, 2017
    Assignee: Sequoia Sciences, Inc.
    Inventors: Russell B Williams, Gary Eldridge, Courtney M. Starks, Peter Robert Guzzo, Zhongping Huang
  • Synthases
    Patent number: 6890752
    Abstract: Novel synthases and the corresponding nucleic acids encoding such synthases are disclosed herein. Such synthases possess an active site pocket that includes key amino acid residues that are modified to generate desired terpenoid reaction intermediates and products. Synthase modifications are designed based on, e.g., the three-dimensional coordinates of tobacco 5-epi-aristolochene synthase. with or without a substrate bound in the active site.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: May 10, 2005
    Assignees: The University of Kentucky Research Foundation, The Salk Institute for Biological Studies
    Inventors: Joseph Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks
  • Synthases
    Publication number: 20040053386
    Abstract: Novel synthases and the corresponding nucleic acids encoding such synthases are disclosed herein. Such synthases possess an active site pocket that includes key amino acid residues that are modified to generate desired terpenoid reaction intermediates and products. Synthase modifications are designed based on, e.g., the three-dimensional coordinates of tobacco 5-epi-aristolochene synthase. with or without a substrate bound in the active site.
    Type: Application
    Filed: June 28, 2001
    Publication date: March 18, 2004
    Applicants: The University of Kentucky Research Foundation and The Salk Institute for Biological Studies, Kentucky and California corporations
    Inventors: Joseph Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks
  • Synthases
    Patent number: 6645762
    Abstract: Novel synthases and the corresponding nucleic acids encoding such synthases are disclosed herein. Such synthases possess an active site pocket that includes key amino acid residues that are modified to generate desired terpenoid reaction intermediates and products. Synthase modifications are designed based on, e.g., the three-dimensional coordinates of tobacco 5-epi-aristolochene synthase, with or without a substrate bound in the active site.
    Type: Grant
    Filed: July 6, 2001
    Date of Patent: November 11, 2003
    Assignees: The Salk Institute for Biological Studies, The University of Kentucky Research Foundation
    Inventors: Joseph Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks
  • Synthases
    Patent number: 6569656
    Abstract: Novel synthases and the corresponding nucleic acids encoding such synthases are disclosed herein. Such synthases possess an active site pocket that includes key amino acid residues that are modified to generate desired terpenoid reaction intermediates and products. Synthase modifications are designed based on, e.g., the three-dimensional coordinates of tobacco 5-epi-aristolochene synthase, with or without a substrate bound in the active site.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: May 27, 2003
    Assignees: The University of Kentucky Research Foundation, The Salk Institute for Biological Studies
    Inventors: Joseph Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks
  • Synthases
    Publication number: 20030087406
    Abstract: Novel synthases and the corresponding nucleic acids encoding such synthases are disclosed herein. Such synthases possess an active site pocket that includes key amino acid residues that are modified to generate desired terpenoid reaction intermediates and products. Synthase modifications are designed based on, e.g., the three-dimensional coordinates of tobacco 5-epi-aristolochene synthase, with or without a substrate bound in the active site.
    Type: Application
    Filed: July 6, 2001
    Publication date: May 8, 2003
    Applicant: The University of Kentucky Research Foundation
    Inventors: Joseph Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks
  • Synthases
    Patent number: 6559297
    Abstract: Novel synthases and the corresponding nucleic acids encoding such synthases are disclosed herein. Such synthases possess an active site pocket that includes key amino acid residues that are modified to generate desired terpenoid reaction intermediates and products. Synthase modifications are designed based on, e.g., the three-dimensional coordinates of tobacco 5-epi-aristolochene synthase, with or without a substrate bound in the active site.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: May 6, 2003
    Assignees: The Salk Institute for Biological Studies, The University of Kentucky Research Foundation
    Inventors: Joseph Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks
  • Synthases
    Patent number: 6495354
    Abstract: Novel synthases and the corresponding nucleic acids encoding such synthases are disclosed herein. Such synthases possess an active site pocket that includes key amino acid residues that are modified to generate desired terpenoid reaction intermediates and products. Synthase modifications are designed based on, e.g., the three-dimensional coordinates of tobacco 5-epi-aristolochene synthase with or without a substrate bound in the active site.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: December 17, 2002
    Assignees: University of Kentucky Research Foundation, The Salk Institute for Biological Studies
    Inventors: Joseph Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks
  • Methods of making modified polypeptides
    Patent number: 6468772
    Abstract: Novel polypeptides and the corresponding nucleic acids encoding such polypeptides are disclosed herein. The invention provides methods of making modified polypeptides by altering one or more amino acid residues involved in the active site of a preselected polypeptide.
    Type: Grant
    Filed: September 17, 1999
    Date of Patent: October 22, 2002
    Assignees: The Salk Institute for Biological Studies, The University of Kentucky Research Foundation
    Inventors: Joseph Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks
  • Synthases
    Publication number: 20020094557
    Abstract: Novel synthases and the corresponding nucleic acids encoding such synthases are disclosed herein. Such synthases possess an active site pocket that includes key amino acid residues that are modified to generate desired terpenoid reaction intermediates and products. Synthase modifications are designed based on, e.g., the three-dimensional coordinates of tobacco 5-epi-aristolochene synthase. with or without a substrate bound in the active site.
    Type: Application
    Filed: July 11, 2001
    Publication date: July 18, 2002
    Applicant: The University of Kentucky Research Foundation
    Inventors: Joseph Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks
  • Synthases
    Publication number: 20020094556
    Abstract: Novel synthases and the corresponding nucleic acids encoding such synthases are disclosed herein. Such synthases possess an active site pocket that includes key amino acid residues that are modified to generate desired terpenoid reaction intermediates and products. Synthase modifications are designed based on, e.g., the three-dimensional coordinates of tobacco 5-epi-aristolochene synthase with or without a substrate bound in the active site.
    Type: Application
    Filed: June 22, 2001
    Publication date: July 18, 2002
    Applicant: The University of Kentucky Research Foundation
    Inventors: Joseph Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks
  • Synthases
    Publication number: 20020040488
    Abstract: Novel synthases and the corresponding nucleic acids encoding such synthases are disclosed herein. Such synthases possess an active site pocket that includes key amino acid residues that are modified to generate desired terpenoid reaction intermediates and products. Synthase modifications are designed based on, e.g., the three-dimensional coordinates of tobacco 5-epi-aristolochene synthase, with or without a substrate bound in the active site.
    Type: Application
    Filed: June 29, 2001
    Publication date: April 4, 2002
    Applicant: The University of Kentucky Research Foundation, Kentucky corporation
    Inventors: Joseph Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks