Patents by Inventor Craig A. Erickson

Craig A. Erickson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REFINED USES OF GABA A RECEPTOR MODULATORS IN TREATMENT OF FRAGILE X SYNDROME
    Publication number: 20230414611
    Abstract: Identification of Fragile X syndrome (FXS) patients who are likely to respond to a treatment involving a GABAA receptor modulator (e.g., a selective GABAA receptor stimulator), for example, at a low dose, using peripheral Fragile X mental retardation protein (FMRP) as a biomarker, either taken alone or in combination with other biomarkers. Also provided here are methods for treating such FXS patients using the GABAA receptor modulator (e.g., a selective GABAA receptor stimulator at a low dose).
    Type: Application
    Filed: November 12, 2021
    Publication date: December 28, 2023
    Applicant: CHILDREN'S HOSPITAL MEDICAL CENTER
    Inventors: Craig A. ERICKSON, Christina GROSS, Ernest PEDAPATI, Lauren SCHMITT
  • COMBINATION THERAPY USING ACAMPROSATE AND D-CYCLOSERINE
    Publication number: 20200360316
    Abstract: The invention provides a method for treating a medical condition in a patient, the method comprising: administering to a patient in need (thereof a pharmaceutical composition comprising a therapeutically effective amount of (i) a first therapeutic agent which is acamprosate or a pharmaceutically acceptable salt thereof and (ii) a second therapeutic agent which is D-cycloserine, a salt of D-cycloserine, an ester of D-cycloserine, an alkylated D-cycloserine, or a precursor of D-cycloserine.
    Type: Application
    Filed: June 2, 2020
    Publication date: November 19, 2020
    Inventors: Steven L. JOHNS, Craig A. ERICKSON
  • COMBINATION THERAPY USING ACAMPROSATE AND D-CYCLOSERINE
    Publication number: 20180221315
    Abstract: Described herein is a method for treating a medical condition in a patient, the method comprising: administering to a patient in need (thereof a pharmaceutical composition comprising a therapeutically effective amount of (i) a first therapeutic agent which is acamprosate or a pharmaceutically acceptable salt thereof and (ii) a second therapeutic agent which is D-cycloserine, a salt of D-cycloserine, an ester of D-cycloserine, an alkylated D-cycloserine, or a precursor of D-cycloserine.
    Type: Application
    Filed: August 4, 2016
    Publication date: August 9, 2018
    Inventors: Steven L. JOHNS, Craig A. ERICKSON
  • Material and methods for treating developmental disorders including comorbid and idiopathic autism
    Patent number: 9956189
    Abstract: The present invention is directed to a method of treating a subject with autism spectrum disorder by administering an acetylaminopropane sulfonate.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: May 1, 2018
    Assignee: Indiana University Research and Technology Corporation
    Inventor: Craig A. Erickson
  • Modulation sAPP, sAAP ? and BDNF levels in individuals diagnosed with FXS and ASD
    Patent number: 9770423
    Abstract: A method of treating and monitoring patient diagnosed with Autistic Spectrum disorder or Fragile X syndrome comprising measuring plasma biomarker levels of BDNF, sAPP, and sAPP alpha and adjusting the amount of a therapeutic compound according to the plasma levels of BDNF, sAPP and sAPPs. In one embodiment, the therapeutic compound is acamprosate.
    Type: Grant
    Filed: July 22, 2013
    Date of Patent: September 26, 2017
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Craig A. Erickson, Debomoy K. Lahiri
  • MATERIAL AND METHODS FOR TREATING DEVELOPMENTAL DISORDERS INCLUDING COMORBID AND IDIOPATHIC AUTISM
    Publication number: 20160303057
    Abstract: Subjects who were diagnosed with either comorbid or idiopathic autism were treated with acamprosate. Patients generally showed marked improvements in primary outcomes as assessed using, for example, standard clinic measures for functionality including the Clinical Global Impressions Improvement (CGI-I) and the Clinical Global Impressions Severity (CGI-S) scales.
    Type: Application
    Filed: June 24, 2016
    Publication date: October 20, 2016
    Applicant: Indiana University Research and Technology Corporation
    Inventor: Craig A. Erickson
  • Material and methods for treating developmental disorders including comorbid and idiopathic autism
    Patent number: 9463172
    Abstract: The present invention is directed to a method of treating a subject with autism spectrum disorder by administering an acetylaminopropane sulfonate.
    Type: Grant
    Filed: February 12, 2010
    Date of Patent: October 11, 2016
    Assignee: Indiana University Research & Technology Corporation
    Inventor: Craig A. Erickson
  • MODULATION SAPP, SAAP ALPHA AND BDNF LEVELS IN INDIVIDUALS DIAGNOSED WITH FXS AND ASD
    Publication number: 20150209312
    Abstract: A method of treating and monitoring patient diagnosed with Autistic Spectrum disorder or Fragile X syndrome comprising measuring plasma biomarker levels of BDNF, sAPP, and sAPP alpha and adjusting the amount of a therapeutic compound according to the plasma levels of BDNF, sAPP and sAPPs. In one embodiment, the therapeutic compound is acamprosate.
    Type: Application
    Filed: July 22, 2013
    Publication date: July 30, 2015
    Inventors: Craig A. Erickson, Debomoy K. Lahiri
  • MATERIAL AND METHODS FOR TREATING DEVELOPMENTAL DISORDERS INCLUDING COMORBID AND IDIOPATHIC AUTISM
    Publication number: 20120016036
    Abstract: Subjects who were diagnosed with either comorbid or idiopathic autism were treated with acamprosate. Patients generally showed marked improvements in primary outcomes as assessed using, for example, standard clinic measures for functionality including the Clinical Global Impressions Improvement (CGI-I) and the Clinical Global Impressions Severity (CGI-S) scales.
    Type: Application
    Filed: February 12, 2010
    Publication date: January 19, 2012
    Applicant: Indiana University Research & Technology Corporation
    Inventor: Craig A. Erickson