Abstract: A storage container securing system, in one embodiment, may include a base for receiving at least a portion of a storage container, such as a cooler, and a shelf adjustably positioned within the base to adjust the location of the storage container. In another embodiment, a storage container securing system is described having slidable inserts configured to matingly engage a slot in a storage container. In another embodiment, a storage container securing system is described having a receiving slot configured to receive a protrusion of a storage container.

Abstract: An exemplary modular container system is provided that includes couplings that may, in one embodiment, be implemented as integrated or interfaced receptacles and corresponding inserts that allow accessory items to couple with a compartment, which may be referred to as a “wet box”, and used as a container that holds items. The accessories may include, for example, a second compartment or “dry box” for holding items that need to be kept dry, a fishing rod holder, a shelf, a cutting board, a cup holder, a chair or seating platform, one or more dollies, or virtually any needed accessory.

Abstract: An exemplary modular container system is provided that includes couplings that may, in one embodiment, be implemented as integrated or interfaced receptacles and corresponding inserts that allow accessory items to couple with a compartment, which may be referred to as a “wet box”, and used as a container that holds items. The accessories may include, for example, a second compartment or “dry box” for holding items that need to be kept dry, a fishing rod holder, a shelf, a cutting board, a cup holder, a chair or seating platform, one or more dollies, or virtually any needed accessory.

Abstract: A storage container securing system, in one embodiment, may include a base for receiving at least a portion of a storage container, such as a cooler, and a shelf adjustably positioned within the base to adjust the location of the storage container. In another embodiment, a storage container securing system is described having slidable inserts configured to matingly engage a slot in a storage container. In another embodiment, a storage container securing system is described having a receiving slot configured to receive a protrusion of a storage container.

Abstract: An exemplary modular cooler system is provided that includes couplings that may, in one embodiment, be implemented as integrated or interfaced receptacles and corresponding inserts that allow accessory items to couple with an insulated compartment, which may be referred to as a “wet box”, and used as an insulated cooler that holds ice. The accessories may include, for example, a second compartment or “dry box” for holding items that need to be kept dry, a fishing rod holder, a shelf, a cutting board, a cup holder, a chair or seating platform, one or more dollies, or virtually any needed accessory. In one embodiment the thermal properties of the insulated compartment are enhanced with the use of one or more radiant barrier members, such as one positioned adjacent the lid of the insulated compartment.

Abstract: An exemplary modular cooler system is provided that includes couplings that may, in one embodiment, be implemented as integrated or interfaced receptacles and corresponding inserts that allow accessory items to couple with an insulated compartment, which may be referred to as a “wet box”, and used as an insulated cooler that holds ice. The accessories may include, for example, a second compartment or “dry box” for holding items that need to be kept dry, a fishing rod holder, a shelf, a cutting board, a cup holder, a chair or seating platform, one or more dollies, or virtually any needed accessory. In one embodiment the thermal properties of the insulated compartment are enhanced with the use of one or more radiant barrier members, such as one positioned adjacent the lid of the insulated compartment.

Abstract: An exemplary modular cooler system is provided that includes couplings that may, in one embodiment, be implemented as integrated or interfaced receptacles and corresponding inserts that allow accessory items to couple with an insulated compartment, which may be referred to as a “wet box”, and used as an insulated cooler that holds ice. The accessories may include, for example, a second compartment or “dry box” for holding items that need to be kept dry, a fishing rod holder, a shelf, a cutting board, a cup holder, a chair or seating platform, one or more dollies, or virtually any needed accessory. In one embodiment the thermal properties of the insulated compartment are enhanced with the use of one or more radiant barrier members, such as one positioned adjacent the lid of the insulated compartment.

Abstract: An exemplary modular cooler system is provided that includes couplings that may, in one embodiment, be implemented as integrated or interfaced receptacles and corresponding inserts that allow accessory items to couple with an insulated compartment, which may be referred to as a “wet box”, and used as an insulated cooler that holds ice. The accessories may include, for example, a second compartment or “dry box” for holding items that need to be kept dry, a fishing rod holder, a shelf, a cutting board, a cup holder, a chair or seating platform, one or more dollies, or virtually any needed accessory. In one embodiment the thermal properties of the insulated compartment are enhanced with the use of one or more radiant barrier members, such as one positioned adjacent the lid of the insulated compartment.

Abstract: An exemplary modular cooler system is provided that includes couplings that may, in one embodiment, be implemented as integrated or interfaced receptacles and corresponding inserts that allow accessory items to couple with an insulated compartment, which may be referred to as a “wet box”, and used as an insulated cooler that holds ice. The accessories may include, for example, a second compartment or “dry box” for holding items that need to be kept dry, a fishing rod holder, a shelf, a cutting board, a cup holder, a chair or seating platform, one or more dollies, or virtually any needed accessory. In one embodiment the thermal properties of the insulated compartment are enhanced with the use of one or more radiant barrier members, such as one positioned adjacent the lid of the insulated compartment.

Abstract: An exemplary modular cooler system is provided that includes couplings that may, in one embodiment, be implemented as integrated or interfaced receptacles and corresponding inserts that allow accessory items to couple with an insulated compartment, which may be referred to as a “wet box”, and used as an insulated cooler that holds ice. The accessories may include, for example, a second compartment or “dry box” for holding items that need to be kept dry, a fishing rod holder, a shelf, a cutting board, a cup holder, a chair or seating platform, one or more dollies, or virtually any needed accessory. In one embodiment the thermal properties of the insulated compartment are enhanced with the use of one or more radiant barrier members, such as one positioned adjacent the lid of the insulated compartment.

Abstract: The present invention provides methods for identifying viral virulence factors and for identifying cellular polypeptides to which the viral polypeptides bind. The cellular polypeptide is useful as a therapeutic target or as a therapeutic agent for treating diseases and disorders, including immunological diseases or disorders.

Abstract: Provide herein are fusion polypeptides that comprise a CD47 extracellular domain or a variant thereof that is fused to a Fc polypeptide. The fusion polypeptides are useful for treating an immunological disease or disorder in a subject according to the methods described herein. The fusion polypeptides are capable of suppressing immunoresponsiveness of an immune cell, inhibiting production of proinflammatory cytokines, including inhibiting immune complex-induced production of cytokines.

Abstract: The present invention provides methods for identifying viral virulence factors and for identifying cellular polypeptides to which the viral polypeptides bind. The cellular polypeptide is useful as a therapeutic target or as a therapeutic agent for treating diseases and disorders, including immunological diseases or disorders.

Abstract: A guard including three sub-systems: a main guard body, a solid shield, and an attachment mechanism. The main guard body includes a base, a peripheral exterior ring, and a plurality of supports for holding the peripheral exterior ring in spaced relationship with the base. Together, the base, the peripheral exterior ring, and the plurality of supports define at least one aperture. The solid shield is attachable to the main guard body. The attachment mechanism is used to attach the main guard body to an extension member of a filament-type trimmer. When positioned, a rotatable non-rigid filament of the filament-type trimmer is peripherally surrounded by the main guard body when the rotatable non-rigid filament is rotating.

Abstract: In-Place Cope Molding or “IPCM,” is designed to reduce or eliminate certain inefficiencies present in traditional molding techniques during production of the cope half of a sand mold. IPCM allows the cope half of the mold to be produced on top of the drag half of the mold by use of a separation barrier which supports the sand above the mold cavity in the drag. This method reduces or eliminates parting line flash, and also avoids the need to turn over or otherwise handle the cope, allowing the cope to be made thinner than a traditional cope and allowing for lower material costs.

Abstract: Provide herein are fusion polypeptides that comprise a CD47 extracellular domain or a variant thereof that is fused to a Fc polypeptide. The fusion polypeptides are useful for treating an immunological disease or disorder in a subject according to the methods described herein. The fusion polypeptides are capable of suppressing immunoresponsiveness of an immune cell, inhibiting production of proinflammatory cytokines, including inhibiting immune complex-induced production of cytokines.

Abstract: A golf ball placement apparatus, for holding and dispensing golf balls onto a tee automatically, comprises a base assembly, a hollow cylinder body attached to the base assembly, and a control arm attached to the base assembly and rotatable through a hinge point. The hollow cylinder body has an open end at top to allow multiple golf balls to be loaded and an open end at bottom to allow a bottom golf ball from said multiple golf balls to be dispensed. When the control arm is rotated downward, the bottom golf ball is forced onto the control arm for setting right onto a tee on the ground. When the control arm is lifted back to the initial up-position, another bottom golf ball from the multiple golf balls is scooped into the scoop ready for next dispensing.

Abstract: Purified protein preparations comprising tumor necrosis factor are disclosed.