Patents by Inventor Craig Anthony CUMMINGS

Craig Anthony CUMMINGS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC AND DIAGNOSTIC METHODS FOR CANCER
    Publication number: 20240288430
    Abstract: The present invention provides therapeutic, diagnostic, and prognostic methods for cancer. The invention provides methods of treating a cancer, methods of determining whether an individual having a cancer is likely to respond to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of predicting responsiveness of an individual having a cancer to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of selecting a therapy for an individual having a cancer, methods of providing a prognosis for an individual having a cancer, and methods of monitoring a response of an individual having a cancer, based on a blood tumor mutational burden (bTMB) score or a maximum somatic allele frequency (MSAF) from a sample (e.g., a whole blood sample, a plasma sample, a serum sample, or a combination thereof) from the individual.
    Type: Application
    Filed: November 17, 2023
    Publication date: August 29, 2024
    Inventors: Craig Anthony CUMMINGS, Yan LI, Sarah Margaret SHAGAN, Erica Beth SCHLEIFMAN, David SHAMES, David FABRIZIO, Daniel LIEBER, Geoffrey Alan OTTO, Mark KENNEDY, Travis CLARK, Doron LIPSON, Jie HE, Shan ZHONG
  • THERAPEUTIC AND DIAGNOSTIC METHODS FOR CANCER
    Publication number: 20190025308
    Abstract: The present invention provides therapeutic, diagnostic, and prognostic methods for cancer. The invention provides methods of treating a cancer, methods of determining whether an individual having a cancer is likely to respond to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of predicting responsiveness of an individual having a cancer to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of selecting a therapy for an individual having a cancer, methods of providing a prognosis for an individual having a cancer, and methods of monitoring a response of an individual having a cancer, based on a blood tumor mutational burden (bTMB) score or a maximum somatic allele frequency (MSAF) from a sample (e.g., a whole blood sample, a plasma sample, a serum sample, or a combination thereof) from the individual.
    Type: Application
    Filed: July 20, 2018
    Publication date: January 24, 2019
    Inventors: Craig Anthony CUMMINGS, Yan LI, Sarah Margaret PAUL, Erica Beth SCHLEIFMAN, David SHAMES, David FABRIZIO, Daniel LIEBER, Geoffrey Alan OTTO, Mark KENNEDY, Travis CLARK, Doron LIPSON, Jie HE, Shan ZHONG