Abstract: In some embodiments, the disclosure relates generally to compositions, comprising a single reaction mixture containing a plurality of different populations of discrete supports, and a plurality of different populations of target nucleic acids. The single reaction mixture can contain a first population of beads; a second population of beads; a first population of target nucleic acids, where at least two different target nucleic acids in the first population of target nucleic acids can bind to a bead in the first population of beads; and a second population of target nucleic acids, where at least two different target nucleic acids in the second population of target nucleic acids can bind to a bead in the second population of beads. The single reaction mixture can be employed to monoclonally amplify the first target nucleic acids on the first beads, and monoclonally amplify the second target nucleic acids on the second beads.

Abstract: Various types of travel bags are provided with at least one portable self-contained vacuum compression system having a portable vacuum pump powered by a portable, preferably removable, rechargeable battery, a compression connection system, and a vacuum compression bag secured within the interior space of the travel bag. The portable self-contained vacuum compression system allows the user to pack more clothing or compressible goods into their travel bag via the use of vacuum compression. The air inside the compression bag can be evacuated by the attached self-contained vacuum pump assembly which is secured within the travel bag in a manner to hold the self-contained vacuum system within the travel bag's internal dimensions in one embodiment. The vacuum compression system can be held in place via a removable or a fixed frame that permits operation of the vacuum compression system within the internal dimensions of the travel bag.

Abstract: Various types of travel bags are provided with at least one portable self-contained vacuum compression system having a portable vacuum pump powered by a portable, preferably removable, rechargeable battery, a compression connection system, and a vacuum compression bag secured within the interior space of the travel bag. The portable self-contained vacuum compression system allows the user to pack more clothing or compressible goods into their travel bag via the use of vacuum compression. The air inside the compression bag can be evacuated by the attached self-contained vacuum pump assembly which is secured within the travel bag in a manner to hold the self-contained vacuum system within the travel bag's internal dimensions in one embodiment. The vacuum compression system can be held in place via a removable or a fixed frame that permits operation of the vacuum compression system within the internal dimensions of the travel bag.

Abstract: Various types of travel bags are provided with at least one portable self-contained vacuum compression system having a portable vacuum pump powered by a portable, preferably removable, rechargeable battery, a compression connection system, and a vacuum compression bag secured within the interior space of the travel bag. The portable self-contained vacuum compression system allows the user to pack more clothing or compressible goods into their travel bag via the use of vacuum compression. The air inside the compression bag can be evacuated by the attached self-contained vacuum pump assembly which is secured within the travel bag in a manner to hold the self-contained vacuum system within the travel bag's internal dimensions in one embodiment. The vacuum compression system can be held in place via a removable or a fixed frame that permits operation of the vacuum compression system within the internal dimensions of the travel bag.

Abstract: A computing system wirelessly receives data from an ear-wearable device and determines, based on the data received from the ear-wearable device, a current position of the ear-wearable device. Additionally, the computing system determines, based on the current position of the ear-wearable device and data regarding a golf course, golf advice data that provides a recommendation regarding play of the golf course. Furthermore, the computing system wirelessly sends audio data to the ear-wearable device. The audio data represents soundwaves of a vocalization of the golf advice data.

Abstract: A computing system wirelessly receives data from an ear-wearable device and determines, based on the data received from the ear-wearable device, a current position of the ear-wearable device. Additionally, the computing system determines, based on the current position of the ear-wearable device and data regarding a golf course, golf advice data that provides a recommendation regarding play of the golf course. Furthermore, the computing system wirelessly sends audio data to the ear-wearable device. The audio data represents soundwaves of a vocalization of the golf advice data.

Abstract: The present subject matter include methods and apparatus for creating three dimensional digitized models of at least one ear impression, the apparatus comprising a frame, a linear axis mounted to the frame, the linear axis having an axis of motion, a first spindle axis mounted to the frame, the spindle axis having an axis of rotation, wherein the axis of rotation of the first spindle axis is parallel to the axis of motion of the linear axis, a first scanner mounted to the linear axis, the scanner includes a laser for projecting a narrowly localized spot of laser light at a target mounted on the first spindle axis and a sensor array for receiving at least a portion of the laser light reflected from the target and a controller configured to communicate with the first scanner.

Abstract: The present subject matter include methods and apparatus for creating three dimensional digitized models of at least one ear impression, the apparatus comprising a frame, a linear axis mounted to the frame, the linear axis having an axis of motion, a first spindle axis mounted to the frame, the spindle axis having an axis of rotation, wherein the axis of rotation of the first spindle axis is parallel to the axis of motion of the linear axis, a first scanner mounted to the linear axis, the scanner includes a laser for projecting a narrowly localized spot of laser light at a target mounted on the first spindle axis and a sensor array for receiving at least a portion of the laser light reflected from the target and a controller configured to communicate with the first scanner.

Abstract: Methods are provided for screening for the necessity for further diagnosis of one or more diseases or conditions in a subject, which methods are based on the discovery that abnormal levels of selected analytes in a sample fluid from a subject can be correlated with specific diseases or conditions. Further provided are criteria, and methods for the determine thereof, for selected analytes with respect to selected diseases or conditions. Thus, a variety of diseases or conditions can be screened in a rapid, cost-effective composite assay. The methods are useful for screening of newborn humans for a variety of diseases and conditions, whereby additional diagnostic procedures need only be conducted for those diseases or conditions indicated by the methods of the invention.

Abstract: The present subject matter include methods and apparatus for creating three dimensional digitized models of at least one ear impression, the apparatus comprising a frame, a linear axis mounted to the frame, the linear axis having an axis of motion, a first spindle axis mounted to the frame, the spindle axis having an axis of rotation, wherein the axis of rotation of the first spindle axis is parallel to the axis of motion of the linear axis, a first scanner mounted to the linear axis, the scanner includes a laser for projecting a narrowly localized spot of laser light at a target mounted on the first spindle axis and a sensor array for receiving at least a portion of the laser light reflected from the target and a controller configured to communicate with the first scanner.

Abstract: The present subject matter include methods and apparatus for creating three dimensional digitized models of at least one ear impression, the apparatus comprising a frame, a linear axis mounted to the frame, the linear axis having an axis of motion, a first spindle axis mounted to the frame, the spindle axis having an axis of rotation, wherein the axis of rotation of the first spindle axis is parallel to the axis of motion of the linear axis, a first scanner mounted to the linear axis, the scanner includes a laser for projecting a narrowly localized spot of laser light at a target mounted on the first spindle axis and a sensor array for receiving at least a portion of the laser light reflected from the target and a controller configured to communicate with the first scanner.

Abstract: A biochemical image is derived from specimens, preferably obtained from a statistically relevant sample of a subject population sharing a common characteristic. The biochemical images for one or more conditions present in the subject population and/or one or more test subjects are determined and made available for computer implemented diagnostic evaluations and medical research. In addition to using the information for general research purposes, information from the images may be used to classify diseases and disease states.