Abstract: Systems, devices, and methods for treating a patient are disclosed. The systems can include a cryotherapy apparatus for selectively treating targeted tissue. The cryotherapy apparatus includes one or more stress relief couplings located along a conduit to help keep an applicator positioned at a treatment site without significant rotational torque being imparted to the applicator by the conduit so that the applicator does not tend to move relative to patient skin during a tissue treatment. The stress relief couplings can include swivel connectors and clamps that cooperate to minimize or limit a rotational force exerted on the applicator by the conduit after the applicator is applied to the patient's skin.

Abstract: Disclosed are two-handed IUD insertion devices for positioning an intrauterine device (IUD) in the uterus which includes a plunger, a sheath, a grip and a handle where the axial movement of the plunger is controlled via features along the length of the plunger in communication with a grip feature.

Abstract: This invention relates generally to the use of ITK (IL-2 inducible T-cell kinase) inhibitors for the treatment of patients who have melanoma or other solid tumors. Applicants demonstrate that ITK lentiviral small hairpin RNA knockdowns and a small molecule inhibitor can each decrease the proliferation and migration of melanoma cell lines and a small molecule inhibitor can be used to inhibit the growth of melanomas in vivo.

Abstract: A method for automatic execution of at least one program associated with a mounted medium, wherein the mounted medium is ejected from a device is provided. The method may include determining if an automatic program initiation on eject is required, wherein the determining is based on a detection of the mounted medium being mounted in the device. The method may also include registering the required automatic program initiation on eject, wherein the registering is based on the determination of the automatic program initiation on eject being required. The method may include storing an executable program content associated with the registered automatic program initiation on eject. Additionally, the method may include executing the stored executable program content, wherein the execution is based on a detection of the mounted medium being ejected from the device. The method may include deregistering the required automatic program initiation on eject.

Abstract: A method for diagnosing an error associated with a software is provided. The method may include receiving a stack trace associated with the error. The method may also include fetching a source code associated with the received stack trace. The method may further include parsing the fetched source code associated with the received stack trace. The method may also include generating an abstract syntax tree (AST) based on the parsed fetched source code. Additionally, the method may include inserting at least one logging call into the generated abstract tree. The method may include recompiling the captured code based on the generated abstract tree with the at least one inserted logging call. The method may also include uploading the recompiled code onto at least one deployment server.

Abstract: A method for diagnosing an error associated with a software is provided. The method may include receiving a stack trace associated with the error. The method may also include fetching a source code associated with the received stack trace. The method may further include parsing the fetched source code associated with the received stack trace. The method may also include generating an abstract syntax tree (AST) based on the parsed fetched source code. Additionally, the method may include inserting at least one logging call into the generated abstract tree. The method may include recompiling the captured code based on the generated abstract tree with the at least one inserted logging call. The method may also include uploading the recompiled code onto at least one deployment server.

Abstract: Systems, devices, and methods for treating a patient are disclosed. The systems can include a cryotherapy apparatus for selectively treating targeted tissue. The cryotherapy apparatus includes one or more stress relief couplings located along a conduit to help keep an applicator positioned at a treatment site without significant rotational torque being imparted to the applicator by the conduit so that the applicator does not tend to move relative to patient skin during a tissue treatment. The stress relief couplings can include swivel connectors and clamps that cooperate to minimize or limit a rotational force exerted on the applicator by the conduit after the applicator is applied to the patient's skin.

Abstract: This invention relates generally to the use of ITK (IL-2 inducible T-cell kinase) inhibitors for the treatment of patients who have melanoma or other solid tumors. Applicants demonstrate that ITK lentiviral small hairpin RNA knockdowns and a small molecule inhibitor can each decrease the proliferation and migration of melanoma cell lines and a small molecule inhibitor can be used to inhibit the growth of melanomas in vivo.

Abstract: A method for diagnosing an error associated with a software is provided. The method may include receiving a stack trace associated with the error. The method may also include fetching a source code associated with the received stack trace. The method may further include parsing the fetched source code associated with the received stack trace. The method may also include generating an abstract syntax tree (AST) based on the parsed fetched source code. Additionally, the method may include inserting at least one logging call into the generated abstract tree. The method may include recompiling the captured code based on the generated abstract tree with the at least one inserted logging call. The method may also include uploading the recompiled code onto at least one deployment server.

Abstract: A method for diagnosing an error associated with a software is provided. The method may include receiving a stack trace associated with the error. The method may also include fetching a source code associated with the received stack trace. The method may further include parsing the fetched source code associated with the received stack trace. The method may also include generating an abstract syntax tree (AST) based on the parsed fetched source code. Additionally, the method may include inserting at least one logging call into the generated abstract tree. The method may include recompiling the captured code based on the generated abstract tree with the at least one inserted logging call. The method may also include uploading the recompiled code onto at least one deployment server.

Abstract: A method for automatic execution of at least one program associated with a mounted medium, wherein the mounted medium is ejected from a device is provided. The method may include determining if an automatic program initiation on eject is required, wherein the determining is based on a detection of the mounted medium being mounted in the device. The method may also include registering the required automatic program initiation on eject, wherein the registering is based on the determination of the automatic program initiation on eject being required. The method may include storing an executable program content associated with the registered automatic program initiation on eject. Additionally, the method may include executing the stored executable program content, wherein the execution is based on a detection of the mounted medium being ejected from the device. The method may include deregistering the required automatic program initiation on eject.

Abstract: A blood glucose test device with viewing lens seal includes a meter body rigid portion of a first polymeric material and an opening. A resilient portion of a second polymeric material more compressible than the first polymeric material integrally connected to the rigid portion defines a rigid portion outer covering. A resilient portion edge extends beyond the rigid portion and partially into the opening about a perimeter of the opening. A transparent polymeric material lens has an outer perimeter surface in contact with the resilient portion edge. Multiple flexible arms extending from the lens each have a hook member. Each hook member engages a receiving member positioned in a meter body and is retained by multiple backup ribs. Hook member engagement at a locking position pulls the lens toward the edge partially compressing the second polymeric material and creating a fluid seal between the perimeter surface and edge.

Abstract: A linen fastener, including: a hub; and a magnet at least partially disposed within the hub. The hub is arranged to be placed against a first exterior surface of layered linens such that magnetic force from the magnet engages an element located on a second exterior surface of the layered linens, opposite the first exterior surface, to clamp the layered linens between the hub and the element. A method of fastening linen using a fastener including a hub and a magnet at least partially disposed within the hub, including: placing the hub against a first exterior surface of layered linens; engaging, with magnetic force from the magnet, an element located on a second exterior surface of the layered linens, opposite the first exterior surface; and clamping the layered linens between the hub and the element.

Abstract: A plastic pallet having a deck and underside with numerous runners having arched members in the base of orifices in the runners. The pallet preferably has a corresponding concave entry in the underside of the deck forming the top of each orifice. The concave entries are substantially equidistant from the arched top portion of the base member. The pallet may include reinforcement bars that are C-shaped with lips on each end, wherein plastic forms around the edges of the lips. The pallet may have a center runner along a center of the underside of the pallet with two side runners each forming a passageway with the center runner so that all four sides of the pallet are accessible through orifices or passageways. The leading edge of the runner may be slightly angled upwardly to improve conveyability. The pallet may have ribs extending from the deck and underdeck channels, which may be reinforced, oriented at approximately right angles from the ribs.

Abstract: The identification and evaluation of mRNA and protein targets associated with mRNP complexes and implicated in the expression of proteins involved in common physiological pathways is described. Effective targets are useful for treating a disease, condition or disorder associated with the physiological pathway.