Abstract: A system and method are provided for synchronizing read-only folders from a cloud-based server. Users can set permissions when sharing folders with other users. The permissions are enforced by client devices of the users downloading content of the folders from the server. A folder at a user's client from the shared domain may include locally modified content and shared content. Based on an indication of a change by a second user to the folder at the server, the user's client modifies a local folder. To prevent local changes made by the user from being overwritten, the user's client identifies the folder containing locally-modified content as a local content folder not to be synchronized between the plurality of clients.

Abstract: A system and method are provided for synchronizing read-only folders from a cloud-based server. Users can set permissions when sharing folders with other users. The permissions are enforced by client devices of the users downloading content of the folders from the server. A folder at a user's client from the shared domain may include locally modified content and shared content. Based on an indication of a change by a second user to the folder at the server, the user's client modifies a local folder. To prevent local changes made by the user from being overwritten, the user's client identifies the folder containing locally-modified content as a local content folder not to be synchronized between the plurality of clients.

Abstract: A system and method are provided for synchronizing read-only folders from a cloud-based server. Users can set permissions when sharing folders with other users. The permissions are enforced by client devices of the users downloading content of the folders from the server. A folder at a user's client from the shared domain may include locally modified content and shared content. Based on an indication of a change by a second user to the folder at the server, the user's client modifies a local folder. To prevent local changes made by the user from being overwritten, the user's client identifies the folder containing locally-modified content as a local content folder not to be synchronized between the plurality of clients.

Abstract: A system and method are provided for synchronizing read-only folders from a cloud-based server. Users can set permissions when sharing folders with other users. The permissions are enforced by client devices of the users downloading content of the folders from the server. A folder at a user's client from the shared domain may include locally modified content and shared content. Based on an indication of a change by a second user to the folder at the server, the user's client modifies a local folder. To prevent local changes made by the user from being overwritten, the user's client identifies the folder containing locally-modified content as a local content folder not to be synchronized between the plurality of clients.

Abstract: A system and method are provided for synchronizing read-only folders from a cloud-based server. Users can set permissions when sharing folders with other users. The permissions are enforced by client devices of the users downloading content of the folders from the server. A folder at a user's client from the shared domain may include locally modified content and shared content. Based on an indication of a change by a second user to the folder at the server, the user's client modifies a local folder. To prevent local changes made by the user from being overwritten, the user's client identifies the folder containing locally-modified content as a local content folder not to be synchronized between the plurality of clients.

Abstract: A system and method are provided for synchronizing read-only folders from a cloud-based server. Users can set permissions when sharing folders with other users. The permissions are enforced by client devices of the users downloading content of the folders from the server. A folder at a user's client from the shared domain may include locally modified content and shared content. Based on first permission assigned to a user for the folder, when an indication of a change by a second user to the folder at the server is received, the user's client propagates the change to shared content below the folder in a folder hierarchy at the user's client. To prevent local changes made by the user from being overwritten, the user's client identifies the folder containing locally-modified content as a local content folder not to be synchronized between the plurality of clients.

Abstract: The present disclosure relates to compounds comprising (i) an active agent, wherein the active agent includes a charge at a predetermined pH, (ii) a polymer, wherein the polymer includes an opposite charge than the active agent at the predetermined pH; and (iii) a polyplex comprising the peptide and the polymer electrostatically bond together at the predetermined pH. In some embodiments, the active agent is a peptide, such as a peptide comprising MAPKAP kinase II inhibitory peptide, and in some embodiments the peptide includes a cell-penetrating peptide. In further embodiments, the disclosure provides methods for treating a disease or condition by administering a composition according to the present disclosure to a subject in need thereof.

Abstract: A system and method are provided for synchronizing read-only folders from a cloud-based server. Users can set permissions when sharing folders with other users. The permissions are enforced by client devices of the users downloading content of the folders from the server. A folder at a user's client from the shared domain may include locally modified content and shared content. Based on first permission assigned to a user for the folder, when an indication of a change by a second user to the folder at the server is received, the user's client propagates the change to shared content below the folder in a folder hierarchy at the user's client. To prevent local changes made by the user from being overwritten, the user's client identifies the folder containing locally-modified content as a local content folder not to be synchronized between the plurality of clients.

Abstract: A system and method are provided for synchronizing read-only folders from a cloud-based server. Users can set read-only permissions when sharing folders with other users. The read-only permissions are enforced by client devices of the users downloading content of the folders from the server. To prevent local changes made by a user having read-only access to a folder from being overwritten, the user's client identifies modified folders as local content. After identifying a modified folder as local content, the client may retrieve the original folder from the cloud-based server.

Abstract: A system and method are provided for synchronizing read-only folders from a cloud-based server. Users can set read-only permissions when sharing folders with other users. The read-only permissions are enforced by client devices of the users downloading content of the folders from the server. To prevent local changes made by a user having read-only access to a folder from being overwritten, the user's client identifies modified folders as local content. After identifying a modified folder as local content, the client may retrieve the original folder from the cloud-based server.

Abstract: A system and method are provided for synchronizing read-only folders from a cloud-based server. Users can set read-only permissions when sharing folders with other users. The read-only permissions are enforced by client devices of the users downloading content of the folders from the server. To prevent local changes made by a user having read-only access to a folder from being overwritten, the user's client identifies modified folders as local content. After identifying a modified folder as local content, the client may retrieve the original folder from the cloud-based server.

Abstract: The present disclosure relates to compounds comprising (i) an active agent, wherein the active agent includes a charge at a predetermined pH, (ii) a polymer, wherein the polymer includes an opposite charge than the active agent at the predetermined pH; and (iii) a polyplex comprising the peptide and the polymer electrostatically bond together at the predetermined pH. In some embodiments, the active agent is a peptide, such as a peptide comprising MAPKAP kinase II inhibitory peptide, and in some embodiments the peptide includes a cell-penetrating peptide. In further embodiments, the disclosure provides methods for treating a disease or condition by administering a composition according to the present disclosure to a subject in need thereof.

Abstract: A system and method are provided for synchronizing read-only folders from a cloud-based server. Users can set read-only permissions when sharing folders with other users. The read-only permissions are enforced by client devices of the users downloading content of the folders from the server. To prevent local changes made by a user having read-only access to a folder from being overwritten, the user's client identifies modified folders as local content. After identifying a modified folder as local content, the client may retrieve the original folder from the cloud-based server.