Abstract: Compositions and methods are provided for diagnosis and/or prognosis of cardiovascular diseases or events in a subject. In some embodiments, the method includes measuring and comparing the level of particular proteins to other proteins. In other embodiments, the method includes comparison with clinical variable information.

Abstract: A dishwasher appliance includes a wash tub that defines a wash chamber, a sump for collecting wash fluid, a wash pump assembly in fluid communication with the sump for circulating the wash fluid, a diverter assembly fluidly coupled to the wash pump assembly for selectively directing the wash fluid, and a hydraulic manifold assembly fluidly coupled to the diverter assembly. The hydraulic manifold assembly includes a lower portion positioned over a diverter housing of the diverter assembly to at least partially define a diverter chamber of the diverter assembly and an upper portion joined to the lower portion to define a filter cleaning manifold and one or more spray arm channels.

Abstract: An adaptor includes a body defining a longitudinal axis, and a transverse axis that is normal to the longitudinal axis. The body also has a leading portion defining a lock receiving recess extending transversely at least partially through the leading portion. The leading portion defines at least one linear portion in the lock receiving recess that is configured to engage the power locking device.

Abstract: The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Abstract: A control system for a vehicle may include a plurality of vehicle subsystems associated with respective different dynamic vehicle control functions and a plurality of subsystem controllers associated with respective ones of the vehicle subsystems. The subsystem controllers may be configured to control actuators associated with the respective different dynamic vehicle control functions to change an operational state of components of the vehicle subsystems based on respective configuration settings. The system further includes an attribute configuration module operably coupled to the subsystem controllers. The attribute configuration module may include processing circuitry configured to save current configuration settings as a saved configuration responsive to a first actuation of a configuration mode actuator and, after an on/off cycle of the vehicle, instruct the subsystem controllers to implement the saved configuration responsive to a second actuation of the configuration mode actuator.

Abstract: The present disclosure relates to a footbed for an article of footwear, the footbed having an arch portion defined by a curve, wherein a height of the curve is adjustable to increase or decrease the height of the arch portion.

Abstract: Methods, devices, and systems for laser eye surgery generally make use of a console that interchangeably accepts multiple types of eye treatment cassettes. The cassettes enable one or both of displacement-based or vacuum-based aspiration. The console and the cassette may communicate to establish the functionality of the installed cassette by utilizing a component indigenous to the operation of the cassette. A dual-mode cassette may include a separable holding tank for enabling vacuum-based aspiration. A displacement-based pump may be provided to drain the holding tank while the vacuum system continues to aspirate fluids. A vacuum sensor for controlling the flow of aspirated fluids may have three ports for communicating with a handpiece, a displacement-based pump, a vacuum-based pump, or an irrigation source. The handpiece may be vented during vacuum-based aspiration by opening a vent valve interposed between the handpiece and the vacuum source.

Abstract: A photon source for promoting the growth and maturation rate of members of the Plantae and Protista Kingdoms comprises a new luminous power source that provides the full range of light spectra by mimicking sunlight in a sunfleck (dappled) pattern by exciting xenon gas inside of an enclosed glass tube in instantaneous pulsed sequences. The micro-dose pulse penetrates the leaf strata to reach the maximum amount of photon processing pigments, provides the energy required for growth by enhancing photosynthetic plant functions, and significantly reducing production energy consumption. The pulse also allows the plant or Protista's photon processing compounds to process the photosynthesis reaction before the next flash, which allows for optimal use of the energy provided. The pulsed lighting sequences reduce energy consumption by up to 90%, and this makes it an excellent application for solar, wind or other green energy power thus reducing carbon footprint and making it the future of the CEA industry.

Abstract: An apparatus for generating and providing a pressurized breathable gas to a patient's airways includes a respiratory pressure therapy (RPT) device having an engagement port pneumatically and electrically coupled to the RPT device, and an air delivery tube configured to engage the engagement port so as to pass a flow of breathable gas to a patient interface. The air delivery tube includes electric contacts associated with a heating and/or a sensing arrangement. The air delivery tube includes a locking collar rotatably movable between (1) an unlocked position to allow connection/disconnection of the air delivery tube to/from the engagement port, and (2) a locked position to releasably lock the air delivery tube to the engagement port. The air delivery tube is structured and arranged to, when the locking collar is rotated into the locked position, pneumatically connect to the engagement port and define an operational configuration of the apparatus.

Abstract: An appliance and methods for operating the appliance in a safety-critical operation are provided. The appliance and methods for operating the appliance include features that provide safe and intuitive ways to initiate and cancel safety-critical operations performed by the appliance.

Abstract: An apparatus for generating and providing a pressurized breathable gas to a patient's airways includes a respiratory pressure therapy (RPT) device having an engagement port pneumatically and electrically coupled to the RPT device, and an air delivery tube configured to engage the engagement port so as to pass a flow of breathable gas to a patient interface. The air delivery tube includes electric contacts associated with a heating and/or a sensing arrangement. The air delivery tube includes a locking collar rotatably movable between (1) an unlocked position to allow connection/disconnection of the air delivery tube to/from the engagement port, and (2) a locked position to releasably lock the air delivery tube to the engagement port. The air delivery tube is structured and arranged to, when the locking collar is rotated into the locked position, pneumatically connect to the engagement port and define an operational configuration of the apparatus.

Abstract: An apparatus for treatment of a respiratory condition, the apparatus comprising: a pressure generator configured to generate a flow of breathable gas; an intermediate component pneumatically connected to an air delivery tube, the intermediate component comprising a port configured to facilitate propagation of sound outside of the intermediate component; a sensor attached externally to the intermediate component and located adjacent to the port of the intermediate component, the sensor configured to sense sound propagated through the air delivery tube; and a controller. The controller can be configured to: receive a sound signal generated by the sensor as a result of sensing sound during operation of the apparatus, analyse the received sound signal, and effect a response based at least in part on the analysing.

Abstract: A method of storing energy is disclosed. The method comprises heating a material that comprises a CO2 sorbed product and an additive to desorb CO2 from the material and to convert the CO2 sorbed product to a CO2 sorbent. The additive is selected such that it at least partially prevents during heating (i) sintering of the CO2 sorbent and/or the CO2 sorbed product; and (ii) the formation of a crust on the material, the crust minimising or preventing the CO2 sorbent and CO2 from reacting with one another to form the CO2 sorbed product in a subsequent CO2 absorption step. Also disclosed is a composition used to sorb and desorb CO2 in a thermal battery, and a system for implementing the method, the system using the composition.

Abstract: A control system for a vehicle may include a plurality of vehicle subsystems associated with respective different dynamic vehicle control functions and a plurality of subsystem controllers associated with respective ones of the vehicle subsystems. The subsystem controllers may be configured to control actuators associated with the respective different dynamic vehicle control functions to change an operational state of components of the vehicle subsystems based on respective configuration settings. The system further includes an attribute configuration module operably coupled to the subsystem controllers. The attribute configuration module may include processing circuitry configured to save current configuration settings as a saved configuration responsive to a first actuation of a configuration mode actuator and, after an on/off cycle of the vehicle, instruct the subsystem controllers to implement the saved configuration responsive to a second actuation of the configuration mode actuator.

Abstract: An optical imaging system (1) is configured for photographing a sample and includes a lighting module (11) and an imaging module (15). The lighting module (11) is configured for outputting excitation light, the excitation light is configured to excite the sample to generate excited light, the imaging module (15) comprises a time delay integration line scan camera (151), the time delay integration line scan camera (151) is configured to record the excited light. A biochemical substance detection system using the optical imaging system (1) is also provided, improving the detection flux.

Abstract: Disclosed are processes for preparing [(3-hydroxypyridine-2-carbonyl)amino]-alkanoic acids, derivatives, inter alia, 5-aryl substituted and 5-heteroaryl substituted [(3-hydroxypyridine-2-carbonyl]amino}acetic acids. Further disclosed are methods for making prodrugs of [(3-hydroxypyridine-2-carbonyl)-amino]acetic acids, for example, [(3-hydroxypyridine-2-carbonyl]amino}acetic acid esters and {[3-hydroxypyridine-2-carbonyl]amino}acetic acid amides. The disclosed compounds are useful as prolyl hydroxylase inhibitors or for treating conditions wherein prolyl hydroxylase inhibition is desired.

Abstract: A control system for a vehicle may include a plurality of vehicle subsystems associated with respective different dynamic vehicle control functions and a plurality of subsystem controllers associated with respective ones of the vehicle subsystems. The subsystem controllers may be configured to control actuators associated with the respective different dynamic vehicle control functions to change an operational state of components of the vehicle subsystems based on respective configuration settings. The system further includes an attribute configuration module operably coupled to the subsystem controllers. The attribute configuration module may include processing circuitry configured to save current configuration settings as a saved configuration responsive to a first actuation of a configuration mode actuator and, after an on/off cycle of the vehicle, instruct the subsystem controllers to implement the saved configuration responsive to a second actuation of the configuration mode actuator.

Abstract: A biochemical substance analysis system (5) is used to detect biological characteristics of a sample in a flow cell (38), and includes a detection system (51), a scheduling system (53), a biochemical reaction system (55). and a control system (57). The scheduling system (53) is used to schedule the flow cell (38) at different sites, including sites in the detection system (51) and sites in the biochemical reaction system (55). The biochemical reaction system (55) is used to allow the sample to react in the flow cell (38). The detection system (51) is used to detect a signal from the reacted sample to obtain a signal representing the biological characteristics of the sample. The control system (57) is used to control the detection system (51), the scheduling system (53), and the biochemical reaction system (55) to cooperate. The disclosure improves automation degree and flux of the biochemical substance analysis.

Abstract: An adaptor includes a body defining a longitudinal axis, and a transverse axis that is normal to the longitudinal axis. The body also has a leading portion defining a lock receiving recess extending transversely at least partially through the leading portion. The leading portion defines at least one linear portion in the lock receiving recess that is configured to engage the power locking device.

Abstract: The invention is that of a removable shoe sole and a cycling shoe comprising said removable shoe sole, wherein the removable shoe sole may be affixed to the bottom of the cycling shoe to enable the wearer to gain traction on surfaces such as muddy ground surfaces. The removable shoe sole may be unitary or modular in design and comprises traction means such as anterior, medial and posterior traction means for enabling a cyclist to quickly affix the removable shoe sold to the bottom of his or her cycling shoes and walk or run across ground surfaces having low traction. The traction means may comprise ridges and valleys or similar means for engaging low-traction ground surfaces. The removable shoe sole may be made of durable material and affixed to a cycling shoe using off-the-shelf fasteners such as will be familiar to one of ordinary skill in the art.