Abstract: A sewing machine assembly includes a sewing machine frame, a presser bar mounted to a frame head of the sewing machine frame, and a feed dog assembly. The feed dog assembly includes a feed dog mounted to the frame base to reciprocate vertically and horizontally relative to the frame base to pull fabric between the pressure bar and the frame base through the sewing machine frame, a feed dog drive system coupled to the feed dog to drive reciprocation of the feed dog relative to the frame base, and a feed dog cover selectively coupled to a frame base of the sewing machine frame to extend over the feed dog to shield the fabric from the feed dog.

Abstract: A sewing machine assembly includes a sewing machine frame, a main presser bar, and a presser foot assembly. The sewing machine frame includes a frame base, a frame body that extends from the frame base, a frame head coupled to the frame body that extends from the frame body toward the frame base. The main presser bar is mounted to the frame head of the sewing machine frame. The presser foot assembly includes an auxiliary presser bar offset from the main presser bar.

Abstract: A method of real-time noise reduction including generating spectral data using temporally localized spectral representations of a received audio signal, determining detection of voice by comparing first and second filtered data, and generating noise-reduced audio output by attenuating noise based on the determined detection of voice. The first and second filtered data are formed by attenuating temporal variations of the spectral data based on, respectively, a first timescale and a second timescale. A noise reduction system, comprising processing circuitry configured to execute a method of real-time noise reduction to generate an output that is transmitted via an output port of the noise reduction system. A noise-reduction microphone comprising a housing having a transducer coupled to a processor therein to execute a method of real-time noise reduction, and an output port. A non-transitory computer-readable medium having instructions to cause a processor to perform a method of real-time noise reduction.

Abstract: A hand-held, rotary fabric cutter includes a handle having a blade end and a grip end opposite the blade end configured to be held by a user to support the cutter during use of the cutter to cut a piece of fabric, a rotary blade, and a blade retention system. The rotary blade is configured to be coupled to the blade end of the handle to rotate about an axis. The blade retention system is configured to selectively couple the rotary blade to the handle.

Abstract: A method of real-time noise reduction including generating spectral data using temporally localized spectral representations of a received audio signal, determining detection of voice by comparing first and second filtered data, and generating noise-reduced audio output by attenuating noise based on the determined detection of voice. The first and second filtered data are formed by attenuating temporal variations of the spectral data based on, respectively, a first timescale and a second timescale. A noise reduction system, comprising processing circuitry configured to execute a method of real-time noise reduction to generate an output that is transmitted via an output port of the noise reduction system. A noise-reduction microphone comprising a housing having a transducer coupled to a processor therein to execute a method of real-time noise reduction, and an output port. A non-transitory computer-readable medium having instructions to cause a processor to perform a method of real-time noise reduction.

Abstract: A method of real-time noise reduction including generating spectral data using temporally localized spectral representations of a received audio signal, determining detection of voice by comparing first and second filtered data, and generating noise-reduced audio output by attenuating noise based on the determined detection of voice. The first and second filtered data are formed by attenuating temporal variations of the spectral data based on, respectively, a first timescale and a second timescale. A noise reduction system, comprising processing circuitry configured to execute a method of real-time noise reduction to generate an output that is transmitted via an output port of the noise reduction system. A noise-reduction microphone comprising a housing having a transducer coupled to a processor therein to execute a method of real-time noise reduction, and an output port. A non-transitory computer-readable medium having instructions to cause a processor to perform a method of real-time noise reduction.

Abstract: A method of real-time noise reduction including generating spectral data using temporally localized spectral representations of a received audio signal, determining detection of voice by comparing first and second filtered data, and generating noise-reduced audio output by attenuating noise based on the determined detection of voice. The first and second filtered data are formed by attenuating temporal variations of the spectral data based on, respectively, a first timescale and a second timescale. A noise reduction system, comprising processing circuitry configured to execute a method of real-time noise reduction to generate an output that is transmitted via an output port of the noise reduction system. A noise-reduction microphone comprising a housing having a transducer coupled to a processor therein to execute a method of real-time noise reduction, and an output port. A non-transitory computer-readable medium having instructions to cause a processor to perform a method of real-time noise reduction.

Abstract: A hand-held, rotary fabric cutter includes a handle having a blade end and a grip end opposite the blade end configured to be held by a user to support the cutter during use of the cutter to cut a piece of fabric, a rotary blade, and a blade retention system. The rotary blade is configured to be coupled to the blade end of the handle to rotate about an axis. The blade retention system is configured to selectively couple the rotary blade to the handle.

Abstract: A first aspect of the invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or ester thereof, (Formula (I)) wherein: R1 is (CH2)mNR11R12; R2 is selected from H, halo, OR13, NHR13, alkyl, alkenyl and alkynyl; R3 is selected from alkyl, alkenyl, alkynyl, aryl, halo, aryloxy, NHCO2R4, NHCONR5R6, NHCOR7, NH-alkyl, NH-alkenyl, NH(CH2);n-aryl, (CH2)p-heteroaryl, (CH2)qCO2R8, (CH2)rCOR9 and NHSO2R10, wherein each alkyl, alkenyl, aryl or heteroaryl moiety in the aforementioned list is optionally further substituted by one or more groups selected from alkyl, halo OH, NH2, alkoxy, aryloxy, alkylamino, arylamino, carboxyl and carboxamide; R4 to R10 and R13 are each independently selected from alkyl, alkenyl and aryl; R11 and R12 are each independently selected from alkyl and alkenyl; or R11 and R:12 are linked together with the nitrogen to which they are attached to form a heterocycloalkyl or heterocycloalkenyl group; n, m, p, q and r are each independently selected from 0, 1, 2, 3, 4, 5

Abstract: A first aspect of the-invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or ester thereof, (Formula (I)) wherein: R1 is (CH2)mNR11R12; R2 is selected from H, halo, OR13, NHR13, alkyl, alkenyl and alkynyl; R3 is selected from alkyl, alkenyl, alkynyl, aryl, halo, aryloxy, NHCO2R4, NHCONR5R6, NHCOR7, NH-alkyl, NH-alkenyl, NH(CH2);n-aryl, (CH2)p-heteroaryl, (CH2)qCO2R8, (CH2)rCOR9 and NHSO2R10, wherein each alkyl, alkenyl, aryl or heteroaryl moiety in the aforementioned list is optionally further substituted by one or more groups selected from alkyl, halo OH, NH2, alkoxy, aryloxy, alkylamino, arylamino, carboxyl and carboxamide; R4 to R10 and R13 are each independently selected from alkyl, alkenyl and aryl; R11 and R12 are each independently selected from alkyl and alkenyl; or R11 and R:12 are linked together with the nitrogen to which they are attached to form a heterocycloalkyl or heterocycloalkenyl group; n, m, p, q and r are each independently selected from 0, 1, 2, .3.