Patents by Inventor Craig H. Warden

Craig H. Warden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection and Use of Prolylcarboxypeptidase
    Publication number: 20080194485
    Abstract: The present invention relates to weight control, control of body fat and food intake, and provides useful methods for treating, inter alia, obesity, diabetes, and conditions, diseases, and disorders relating thereto.
    Type: Application
    Filed: May 23, 2005
    Publication date: August 14, 2008
    Applicants: YALE UNIVERSITY, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Tamas Horvath, Sabrina Diano, Qian Gao, Craig H. Warden
  • Human obesity LIPIN3 polynucleotide and polypeptide sequences and methods of use thereof
    Publication number: 20040018497
    Abstract: The present invention relates to human LIPIN3 polynucleotides, which are involved in the control of mammalian body weight. The invention encompasses LIPIN3 polynucleotide sequences, including altered (mutant) LIPIN3 sequences, and fragments thereof, vectors and host cells comprising LIPIN3 polynucleotides, Lipin3 polypeptides, antibodies that specifically bind to Lipin3 polypeptide, arrays comprising LIPIN3 polynucleotides and polypeptides, and purified cells comprising an altered LIPIN3 polynucleotide. The invention also encompasses methods and compositions for the diagnosis and/or treatment of obesity and obesity related diseases, and for the identification of individuals susceptible to such diseases. The invention also encompasses methods of screening for compounds that alter LIPIN3 expression, preferably reducing LIPIN3 expression, and compounds that modulate the activity of the LIPIN3 gene product.
    Type: Application
    Filed: July 26, 2002
    Publication date: January 29, 2004
    Inventor: Craig H. Warden
  • Respiration uncoupling protein
    Publication number: 20030119775
    Abstract: The present invention relates, in general, to a protein linked to cell respiration, thermogenesis, obesity and hyperinsulinemia and, in particular, to a protein designated uncoupling protein-2 (UCP2) and to nucleic acid sequences encoding same. The invention also relates to diagnostic methodologies based, for example, on a determination of levels of UCP2 expression. Further, the invention relates to therapies involving modulating UCP2 expression and/or activity. In addition, the present invention relates to methods of screening compounds for their suitability for use in such therapies.
    Type: Application
    Filed: October 8, 2002
    Publication date: June 26, 2003
    Applicants: DUKE UNIVERSITY, REGENTS OF THE UNIVERSITY OF CALIFORNIA, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Richard S. Surwit, Sheila A. Collins, Craig H. Warden, Michael F. Seldin, Daniel Ricquier, Frederic Bouillaud