Abstract: A method of manufacturing a therapeutic device includes forming a container wall that is sized to contain multiple cells capable of producing a therapeutic agent within an interior region of the container wall. The method further includes exposing the container wall to a solvent to remove material from the container wall to define first pores along an interior portion of the container wall and second pores along an exterior portion of the container wall. The first pores have a first average size that (i) allows passage of the therapeutic agent through the first pores and (ii) prevents passage of immune cells through the first pores. The second pores have a second average size that is larger than the first average size, and the second pores are sized to promote vascularization along the exterior portion.

Abstract: A method of manufacturing a therapeutic device includes providing a member that defines first pores having a first average size that (i) allows passage of a therapeutic agent through the first pores and (ii) prevents passage of immune cells through the first pores. The method further includes spinning the member about an axis of the member and applying a fibrous material to the member while the member spins to form a coating that surrounds the member. The coating defines second pores having a second average size that is larger than the first average size, and the second pores are sized to promote vascularization along the coating. The member and the coating together form a container of the therapeutic device, and the container defines an interior region for accommodating a plurality of cells capable of producing the therapeutic agent.

Abstract: An implantable device for providing a therapeutic agent includes a container configured to contain multiple cells capable of producing the therapeutic agent within an interior region of the container. The container defines first pores defined by an interior wall portion of the container and second pores defined by an exterior wall portion of the container. The first pores have a first average size that (i) allows passage of the therapeutic agent and oxygen through the first pores and (ii) prevents passage of immune cells through the first pores. The second pores have a second average size that is larger than the first average size, and the second pores are sized to promote vascularization and oxygen transfer along the exterior wall portion.

Abstract: An implantable device for providing a therapeutic agent includes a container configured to contain multiple cells capable of producing the therapeutic agent within an interior region of the container and a substance capable of reacting to generate oxygen for the multiple cells within the interior region of the container. The container defines first pores defined by an interior wall portion of the container and second pores defined by an exterior wall portion of the container. The first pores have a first average size that (i) allows passage of the therapeutic agent through the first pores and (ii) prevents passage of immune cells through the first pores. The second pores have a second average size that is larger than the first average size, and the second pores are sized to promote vascularization along the exterior wall portion.

Abstract: A method of barrier coating a porous substrate, the method comprising: coating a surface of the substrate with an intermediate layer, said intermediate layer filling pores at the surface of the substrate; and coating the intermediate layer with a non-polymer barrier layer.

Abstract: A path finding system using a series of networked receiver beacons is disclosed. The system includes receiver beacons placed on a path. Each of the receiver beacons include a transceiver receiving and sending signals and a location indicator such as a LED, that when activated indicates the location of the receiver beacon. Each of the receiver beacons include a controller coupled to the indicator and the transceiver. The controller is operable to receive an activation signal to activate the indicator. A transmitter is paired with each of the receiver beacons. The transmitter includes a transceiver to send an activation signal to at least one of the receiver beacons. The receiver beacon receives the activation signal and activates the indicator. The receiver beacon also relays the activation signal to at least another receiver beacon.

Abstract: Systems, methods, and devices for analyzing small volumes of fluidic samples, as a non-limiting example, less than twenty microliters are provided. The devices are configured to make a first sample reading, for example, measure an energy property of the fluid sample, for example, osmolality, make a second sample reading, for example, detecting the presence or concentration of one or more analytes in the fluid sample, or make both the first sample reading and the second sample reading, for example, measuring the energy property of the fluid sample as well as detecting the presence or concentration of one or more analytes in the fluid sample.

Abstract: Concepts and technologies are disclosed herein for tag-based security policy creation in a distributed computing environment. A security management module can receive an inventory event that relates to instantiation of a service. The security management module can identify the service that was instantiated and obtain a tag set that relates to the service. The tag set can include security tags that include a string that identifies a communications link associated with the entities included in the service that was instantiated. The security management module can identify policy rules associated with the security tags. The policy rules can define security for the service that was instantiated. The security management module can compute a security policy for the service and can provide the security policy to the computing environment for implementation.

Abstract: A carrier system that includes a multi-curve front body armor plate that is wearable on a front torso having a protruding chest. The strike face has a lower region with a lower convex portion shaped to follow a cylindrical contour of an abdomen and chest of the torso. An upper portion of the strike face laterally tapers to a top edge and curves backwardly to accommodate the protruding chest. An armor carrier of the carrier system includes (i) a back panel; (ii) a front panel having an opening that is sized to receive the multi-curve front body armor plate; and (iii) a shoulder harness connecting the front and back panels. The shoulder harness providing a support surface that rests upon shoulders of a wearer.

Abstract: A path finding system using a series of networked receiver beacons is disclosed. The system includes receiver beacons placed on a path. Each of the receiver beacons include a transceiver receiving and sending signals and a location indicator such as a LED, that when activated indicates the location of the receiver beacon. Each of the receiver beacons include a controller coupled to the indicator and the transceiver. The controller is operable to receive an activation signal to activate the indicator. A transmitter is paired with each of the receiver beacons. The transmitter includes a transceiver to send an activation signal to at least one of the receiver beacons. The receiver beacon receives the activation signal and activates the indicator. The receiver beacon also relays the activation signal to at least another receiver beacon.

Abstract: Concepts and technologies are disclosed herein for providing and using a connection management service. A connection management service can receive a connection request that requests a connection between a requestor and a distributed network. The connection management service can identify a connector to provide the connection between the requestor and the distributed network. The connection management service can provide, to the requestor, an object corresponding to the connector. The requestor can invoke the object to connect to the distributed network.

Abstract: Concepts and technologies are disclosed herein for tag-based security policy creation in a distributed computing environment. A security management module can receive an inventory event that relates to instantiation of a service. The security management module can identify the service that was instantiated and obtain a tag set that relates to the service. The tag set can include security tags that include a string that identifies a communications link associated with the entities included in the service that was instantiated. The security management module can identify policy rules associated with the security tags. The policy rules can define security for the service that was instantiated. The security management module can compute a security policy for the service and can provide the security policy to the computing environment for implementation.

Abstract: Concepts and technologies are disclosed herein for tag-based security policy creation in a distributed computing environment. A security management module can receive an inventory event that relates to instantiation of a service. The security management module can identify the service that was instantiated and obtain a tag set that relates to the service. The tag set can include security tags that include a string that identifies a communications link associated with the entities included in the service that was instantiated. The security management module can identify policy rules associated with the security tags. The policy rules can define security for the service that was instantiated. The security management module can compute a security policy for the service and can provide the security policy to the computing environment for implementation.

Abstract: A method for taking into use an exchangeable supply pack in a beverage dispensing machine is disclosed. The exchangeable supply pack comprising a dosing pump and a container with a liquid substance to be supplied by the beverage dispensing machine. The method subsequently comprises detecting placement of the exchangeable supply pack and executing an activation procedure. The activation procedure comprises repeating an activation cycle while detecting whether or not a liquid substance is present inside the dosing pump. The activation cycle comprises activating the dosing pump during a first period of time and at least partially deactivating the dosing pump during a second period of time. The activation procedure is completed when it is detected that liquid substance is present in the dosing pump. In addition, a beverage dispensing system and a computer program product are disclosed herein.

Abstract: Concepts and technologies are disclosed herein for providing and using a connection management service. A connection management service can receive a connection request that requests a connection between a requestor and a distributed network. The connection management service can identify a connector to provide the connection between the requestor and the distributed network. The connection management service can provide, to the requestor, an object corresponding to the connector. The requestor can invoke the object to connect to the distributed network.

Abstract: A method for taking into use an exchangeable supply pack in a beverage dispensing machine is disclosed. The exchangeable supply pack comprising a dosing pump and a container with a liquid substance to be supplied by the beverage dispensing machine. The method subsequently comprises detecting placement of the exchangeable supply pack and executing an activation procedure. The activation procedure comprises repeating an activation cycle while detecting whether or not a liquid substance is present inside the dosing pump. The activation cycle comprises activating the dosing pump during a first period of time and at least partially deactivating the dosing pump during a second period of time. The activation procedure is completed when it is detected that liquid substance is present in the dosing pump. In addition a beverage dispensing system and a computer program product are disclosed herein.

Abstract: Concepts and technologies are disclosed herein for providing and using a connection management service. A connection management service can receive a connection request that requests a connection between a requestor and a distributed network. The connection management service can identify a connector to provide the connection between the requestor and the distributed network. The connection management service can provide, to the requestor, an object corresponding to the connector. The requestor can invoke the object to connect to the distributed network.

Abstract: Concepts and technologies are disclosed herein for tag-based security policy creation in a distributed computing environment. A security management module can receive an inventory event that relates to instantiation of a service. The security management module can identify the service that was instantiated and obtain a tag set that relates to the service. The tag set can include security tags that include a string that identifies a communications link associated with the entities included in the service that was instantiated. The security management module can identify policy rules associated with the security tags. The policy rules can define security for the service that was instantiated. The security management module can compute a security policy for the service and can provide the security policy to the computing environment for implementation.

Abstract: A particulate sprayer includes a gas reservoir to hold a gas, a liquid reservoir to hold a product, and a low pressure section including an exit opening connected to the liquid reservoir. The product includes a liquid and solid particles. The low pressure section transports gas released from the gas reservoir over the exit opening. The product is drawn, pushed, or drawn and pushed from the exit opening into the transported gas to create a spray of the product to be sprayed from the particulate sprayer.

Abstract: Concepts and technologies are disclosed herein for providing and using a connection management service. A connection management service can receive a connection request that requests a connection between a requestor and a distributed network. The connection management service can identify a connector to provide the connection between the requestor and the distributed network. The connection management service can provide, to the requestor, an object corresponding to the connector. The requestor can invoke the object to connect to the distributed network.