Patents by Inventor Craig Jamieson
Craig Jamieson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10631771Abstract: Methods and apparatus for blood sampling from skin capillaries are provided. Blood extraction is improved by applying gradient pressure in a proximal to distal direction of an extremity. Blood is extracted and sampled from the skin capillaries with a blood sampling mechanism of at least a lancet and testing kit.Type: GrantFiled: January 6, 2009Date of Patent: April 28, 2020Inventors: Morteza Naghavi, Albert Andrew Yen, Haider Hassan, David Panthagani, Craig Jamieson, Gary L. McQuilkin, Timothy J O'Brien
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Patent number: 8952001Abstract: The invention relates to amino-heteroaryl derivatives having the general Formula I or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of these derivatives for the treatment of pain, such as neuropathic pain or inflammatory pain.Type: GrantFiled: December 20, 2010Date of Patent: February 10, 2015Assignee: Merck Sharp & Dohme Corp.Inventors: Simon James Anthony Grove, Angus John Morrison, Craig Jamieson, Ronald Palin, John Kinnaird Ferguson Maclean
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Patent number: 8633237Abstract: The present invention relates to anindane derivative according to formula I wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising one or more of said indane derivatives and to their use in therapy, for instance in the treatment or prevention of psychiatric diseases where an enhancement of synaptic responses mediated by AMPA receptors is required, including schizophrenia, depression and Alzheimer's disease.Type: GrantFiled: April 8, 2010Date of Patent: January 21, 2014Assignee: Merck Sharp & Dohme B.V.Inventors: Kevin J. Gillen, Jonathan Gillespie, Craig Jamieson, John K. F. MacLean, Elizabeth M. Moir, Zoran Rankovic
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Patent number: 8536214Abstract: The present invention relates to a heterocyclic derivative according to formula (I); wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising said heterocyclic derivatives and to their use in therapy, for instance in the treatment or prevention of psychiatric diseases where an enhancement of synaptic responses mediated by AMPA receptors is required, including schizophrenia, depression and Alzheimer's disease.Type: GrantFiled: June 3, 2009Date of Patent: September 17, 2013Inventors: Jonathan Gillespie, Craig Jamieson, John Kinaird Fergusen MaClean, Elizabeth Margaret Moir, Zoran Rankovic
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Publication number: 20120264728Abstract: The invention relates to amino-heteroaryl derivatives having the general Formula I or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of these derivatives for the treatment of pain, such as neuropathic pain or inflammatory pain.Type: ApplicationFiled: December 20, 2010Publication date: October 18, 2012Inventors: Simon James Anthony Grove, Angus John Morrison, Craig Jamieson, Ronald Palin, John Kinnaird Ferguson Maclean
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Publication number: 20120202781Abstract: The present invention relates to anindane derivative according to formula I wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising one or more of said indane derivatives and to their use in therapy, for instance in the treatment or prevention of psychiatric diseases where an enhancement of synaptic responses mediated by AMPA receptors is required, including schizophrenia, depression and Alzheimer's disease.Type: ApplicationFiled: April 8, 2010Publication date: August 9, 2012Inventors: Kevin James Gillen, Jonathan Gillespie, Craig Jamieson, John Kinnaird Ferguson MacLean, Elizabeth Margaret Moir, Zoran Rankovic
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Publication number: 20110092539Abstract: The present invention relates to a heterocyclic derivative according to formula (I); wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising said heterocyclic derivatives and to their use in therapy, for instance in the treatment or prevention of psychiatric diseases where an enhancement of synaptic responses mediated by AMPA receptors is required, including schizophrenia, depression and Alzheimer's disease.Type: ApplicationFiled: June 3, 2009Publication date: April 21, 2011Inventors: Jonathan Gillespie, Craig Jamieson, Zoran Rankovic
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Publication number: 20110059979Abstract: Certain compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, P, P?, X, m and n are as defined in the specification, a process for preparing such compounds, a pharmaceutical composition comprising such compounds and the use of such compounds in medicine.Type: ApplicationFiled: August 12, 2004Publication date: March 10, 2011Applicant: GLAXO GROUP LIMITEDInventors: Craig Jamieson, David Drysdale Miller, Harshad Kantilal Rami, Mervyn Thompson
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Patent number: 7820707Abstract: The present invention relates to a heterocyclic derivative according to formula I wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising said heterocyclic derivatives and to their use in therapy, for instance in the treatment or prevention of psychiatric diseases where an enhancement of synaptic responses mediated by AMPA receptors is required, including schizophrenia, depression and Alzheimer's disease.Type: GrantFiled: June 29, 2007Date of Patent: October 26, 2010Assignee: N.V. OrganonInventors: Kevin James Gillen, Craig Jamieson, John Kinnaird Ferguson MacLean, Elizabeth Margaret Moir, Zoran Rankovic
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Publication number: 20100226449Abstract: This invention provides a method and system for reducing the PAPR. The method involves (i) intentionally inserting error(s) into the time or frequency domain and (ii) employing various bit mapping schemes to provide a significant reduction in the PAPR. An embodiment of the error insertion of the method involves intentionally inserting symbol error(s) into the quadrature amplitude modulation (QAM) symbol stream before applying discrete Fourier transform in OFDM. The method trades off the coding gain of the system for the PAPR reduction of the OFDM signals and does not require transmission of side information. It further has reduced complexity and improved bit error rate (BER) performance when used with a typical non-linear amplifier as compared to alternative existing methods (Gray coding, tone injection, tone reservation, etc.Type: ApplicationFiled: June 27, 2008Publication date: September 9, 2010Applicant: Dalhousie UniversityInventors: Jacek Ilow, Craig Jamieson
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Publication number: 20100081941Abstract: Methods and apparatus for improving measurements of cardiovascular health status in a given individual are provided. The comprehensive assessment of cardiovascular health includes at least two components: risk factor assessment based on epidemiologic studies and functional status of the individual. Structural studies of the individual can also be included in the comprehensive assessment of cardiovascular health. The invention aims to improve detection, treatment, devices, and administration of cardiovascular risk assessment.Type: ApplicationFiled: December 21, 2007Publication date: April 1, 2010Applicant: Endothelix, Inc.Inventors: Morteza Naghavi, Robin Antony Owen, Albert Andrew Yen, Craig Jamieson, Haider Hassan, David Panthagani, Gary L. McQuilkin, Timothy O'Brien
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Publication number: 20090177224Abstract: Methods and apparatus for blood sampling from skin capillaries are provided. Blood extraction is improved by applying gradient pressure in a proximal to distal direction of an extremity. Blood is extracted and sampled from the skin capillaries with a blood sampling mechanism of at least a lancet and testing kit.Type: ApplicationFiled: January 6, 2009Publication date: July 9, 2009Applicant: In3 Ventures, Inc.Inventors: Morteza Naghavi, Albert Yen, Craig Jamieson, Haider A. Hassan, David Panthagani, Gary McQuilkin, Timothy J. O'Brien
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Publication number: 20080255086Abstract: The present invention relates to a heterocyclic derivative according to formula I wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising said heterocyclic derivatives and to their use in therapy, for instance in the treatment or prevention of psychiatric diseases where an enhancement of synaptic responses mediated by AMPA receptors is required, including schizophrenia, depression and Alzheimer's disease.Type: ApplicationFiled: June 29, 2007Publication date: October 16, 2008Applicant: N.V. OrganonInventors: Kevin James Gillen, Craig Jamieson, John Kinnaird Ferguson MacLean, Elizabeth Margaret Moir, Zoran Rankovic
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Publication number: 20080081963Abstract: Methods and apparatus are provided for determining individual responses to induced and actual mental stress and for identifying individuals susceptible to detrimental effects of mental stress on the cardiovascular system. The subjects may be at risk for chronic effects of mental stress by virtue of synergistic effects of mental stress and cardiovascular (CV) disease risk factors) or may be at risk, or vulnerable to, acute effects of mental stress by virtue of synergistic effects of mental stress and underlying hidden coronary atherosclerosis. The invention further provides methods and apparatus for assessing vascular reactivity in individuals under ambulatory conditions and relating mental stress responses to vascular reactivity.Type: ApplicationFiled: September 28, 2007Publication date: April 3, 2008Applicant: ENDOTHELIX, INC.Inventors: Morteza Naghavi, Timothy J. O'Brien, Craig Jamieson, Mark C. Johnson, Haider A. Hassan
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Publication number: 20080027330Abstract: Methods and apparatus are provided for assessing the risk of an acute cardiovascular event that includes providing an endothelial or vascular function test to identify higher risk from lower risk individuals in a population of symptomatic individuals presenting with chest pain that have inconclusive results in ECG and cardiovascular marker tests, such as a tropinin test, and are administered for triage in hospital and additional tests such as ECG exercise and nuclear stress tests. The invention further provides methods and apparatus for assessing the vascular status and response of patients in clinical trials for cardiovascular therapies.Type: ApplicationFiled: May 15, 2007Publication date: January 31, 2008Applicant: ENDOTHELIX, INC.Inventors: Morteza Naghavi, Timothy O'Brien, Craig Jamieson, Mark Johnson, Naser Ahmadi, Haider Hassan
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Publication number: 20070293477Abstract: This invention relates to novel compounds useful in the treatment of diseases associated with TRPV4 channel receptor.Type: ApplicationFiled: September 7, 2005Publication date: December 20, 2007Inventors: Linda Casillas, Craig Jamieson, Robert Marquis
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Publication number: 20070225614Abstract: The present invention provides methods and apparatus for assessing a patient's vascular health including endothelial function by monitoring changes in hemodynamic parameters responsive to the introduction of a vasostimulant. The invention provides a thermal energy measurement apparatus including a thermal energy sensor adapted to measure temperature of a body part while not substantially changing the temperature of the body part, and a display or recorder coupled to the thermal energy sensor, wherein the thermal energy sensor measures the temperature of the body part before and subsequent to the provision of a vasostimulant, and the display or recorder reports the temperature of the body part prior to the provision of the stimulant and the temperature of the body part after provision of the stimulant.Type: ApplicationFiled: November 27, 2006Publication date: September 27, 2007Applicant: ENDOTHELIX, INC.Inventors: Morteza Naghavi, Timothy O'Brien, Craig Jamieson, Mark Johnson
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Publication number: 20070225606Abstract: Apparatus and methods for comprehensive assessment of vascular health is provided including functional status of the individual, risk factor assessment based on epidemiologic studies, and structural studies of the individual. Functional assessment in accordance with an embodiment of the invention includes generation of information on the status of three compartments: the microvasculature, the macrovasculature and the neurovasculature.Type: ApplicationFiled: March 22, 2007Publication date: September 27, 2007Applicant: ENDOTHELIX, INC.Inventors: Morteza Naghavi, Timothy J. O'Brien, Craig Jamieson, Mark C. Johnson, Naser Ahmadi, Haider A. Hassan
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Publication number: 20070173727Abstract: Methods and apparatus are provided for identifying and minimizing neurovascular contributions to determinations of endothelial function, including by digital temperature monitoring such that an accurate status of vascular reactivity can be obtained. Methods are also provided for identifying individuals having increased sympathetic nervous system activity impacting peripheral vascular function as well as for determining a status of diabetic foot.Type: ApplicationFiled: August 14, 2006Publication date: July 26, 2007Applicant: Endothelix Inc.Inventors: Morteza Naghavi, Timothy O'Brien, Craig Jamieson, Mark Johnson
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Publication number: 20070118045Abstract: Methods and apparatus are provided for determining individual vascular responses by employing iontophoresis to deliver vasoactive compounds to local area and determining resultant changes in blood flow by measuring changes in skin temperature as a correlate of local blood flow. The invention further provides methods and apparatus for assessing vascular reactivity in individuals under ambulatory conditions and relating stress responses to vascular reactivity.Type: ApplicationFiled: October 23, 2006Publication date: May 24, 2007Applicant: Endothelix, Inc.Inventors: Morteza Naghavi, Timothy O'Brien, Craig Jamieson, Mark Johnson