Abstract: Insulated package systems, components for such systems, and methods for their assembly and use. The systems include insert panels that are configured to be disposed within an interior volume of a container alongside walls thereof so as to define and enclose an insulated shipping compartment within the interior volume. At least one of insert panels includes a tray portion having a base wall that defines an inner face of the insert panel, and a lid portion having a base wall that optionally defines a recessed pocket exposed at an outer face of the insert panel. An enclosed pocket is disposed between the base walls of the tray and lid portions, and may be filled with an insulation material.