Patents by Inventor Craig M. Gardner

Craig M. Gardner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180228412
    Abstract: A transmission-mode optical spectroscopy method includes illuminating a first face of a skinfold with first light having plural wavelengths and detecting second light that emerges from a second face of the skinfold. The skinfold has a thickness of less than 1.5 millimeters.
    Type: Application
    Filed: February 7, 2018
    Publication date: August 16, 2018
    Inventor: Craig M. Gardner
  • Publication number: 20180221622
    Abstract: A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat polycystic ovarian syndrome (PCOS).
    Type: Application
    Filed: November 14, 2017
    Publication date: August 9, 2018
    Applicant: Fractyl Laboratories, Inc.
    Inventors: Harith Rajagopalan, Jay Caplan, Craig M. Gardner, J. Christopher Flaherty
  • Publication number: 20180193590
    Abstract: A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat at least one of non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).
    Type: Application
    Filed: August 22, 2017
    Publication date: July 12, 2018
    Applicant: Fractyl Laboratories, Inc.
    Inventors: Harith Rajagopalan, Jay Caplan, Craig M. Gardner, J. Christopher Flaherty
  • Patent number: 9844641
    Abstract: A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat polycystic ovarian syndrome (PCOS).
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: December 19, 2017
    Assignee: FRACTYL LABORATORIES, INC.
    Inventors: Harith Rajagopalan, Jay Caplan, Craig M. Gardner, J. Christopher Flaherty
  • Publication number: 20170333122
    Abstract: Systems, device and methods treat target tissue to provide a therapeutic benefit to the patient. A tissue treatment device comprises a tissue treatment element constructed and arranged to treat target tissue, such as duodenal mucosa tissue.
    Type: Application
    Filed: January 13, 2017
    Publication date: November 23, 2017
    Applicant: Fractyl Laboratories, Inc.
    Inventors: Harith Rajagopalan, Jay Caplan, Craig M. Gardner, J. Christopher Flaherty
  • Patent number: 9757535
    Abstract: A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat at least one of non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: September 12, 2017
    Assignee: Fractyl Laboratories, Inc.
    Inventors: Harith Rajagopalan, Jay Caplan, Craig M. Gardner, J. Christopher Flaherty
  • Publication number: 20170014596
    Abstract: A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat polycystic ovarian syndrome (PCOS).
    Type: Application
    Filed: September 23, 2016
    Publication date: January 19, 2017
    Inventors: Harith Rajagopalan, Jay Caplan, Craig M. Gardner, J. Christopher Flaherty
  • Publication number: 20170007310
    Abstract: A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat at least one of non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).
    Type: Application
    Filed: September 23, 2016
    Publication date: January 12, 2017
    Inventors: Harith Rajagopalan, Jay Caplan, Craig M. Gardner, J. Christopher Flaherty
  • Patent number: 9514360
    Abstract: A processing application receives peak information associated with multiple known references samples. The processing application partitions a spectrum into multiple different sized range bins such that a substantially equal number of the peaks associated with the known reference samples reside into each of the multiple different sized range bins. To identify a set of candidate reference samples in a library of reference samples that potentially are a good match an unknown sample under test, the processing application compares peaks associated with the unknown sample to the multiple different sized range bins. The greater the number of range bin matches based on peaks in the unknown sample and peaks in a corresponding reference sample, the greater the likelihood that the unknown sample matches the corresponding reference sample.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: December 6, 2016
    Assignee: Thermo Scientific Portable Analytical Instruments Inc.
    Inventors: Craig M. Gardner, Robert L. Green
  • Patent number: 9400271
    Abstract: A method of detecting an explosive material, and an analyzer and computer program products that may perform such methods. A method may include illuminating at least a portion of the material with light, and monitoring the temperature of the illuminated portion. T power or location of the illuminating light may be altered in response to the monitored temperature. Raman spectral data are produced in response to Raman radiation emitted from the portion in response to the light. The composition of the material may be analyzed based on the Raman spectral data or generating an indication to an operator that the material cannot be safely analyzed.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: July 26, 2016
    Assignee: Thermo Scientific Portable Analytical Instruments Inc.
    Inventors: Craig M. Gardner, Michael Burka
  • Patent number: 9182280
    Abstract: Featured is a method for reducing frequency of taking background spectra in FTIR or FTIR-ATR spectroscopy. Such a method includes determining if there is a pre-existing reference spectrum available and if such a reference spectrum is available, acquiring a present reference scan before acquiring a sample scan. The method also includes comparing the present reference scan with the pre-existing reference spectrum to determine if there is one or more non-conformities therebetween and if there is/are one or more nonconformities, determining if the one or more non-conformities are resolvable or not. If the one or more non-conformities are resolvable; resolve each non-conformity in a determined manner and thereafter acquiring a scan of the sample, and if the non-conformities are not resolvable, then acquiring a new reference sample and thereafter acquiring a scan of the sample.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: November 10, 2015
    Assignee: Thermo Scientific Portable Analytical Instruments Inc.
    Inventors: Craig M. Gardner, Michael Burka
  • Patent number: 9110001
    Abstract: A method, apparatus and computer program product for tagging reference materials of interest in spectroscopic searching applications is presented. A reference list of materials to be considered as part of a final analysis of a spectroscopic analysis of a sample material is generated. A watchlist of at least one material to be retained for a final analysis of the spectroscopic analysis of a sample material is provided. A final analysis of the sample material is preformed using the watchlist of at least one material and the reference list of materials. A determination is then made regarding whether a spectrum of the sample material matches at least one spectrum of materials on the watchlist and on the reference list.
    Type: Grant
    Filed: July 2, 2012
    Date of Patent: August 18, 2015
    Assignee: Thermo Scientific Portable Analytical Instruments Inc.
    Inventors: Robert L. Green, Michael D. Hargreaves, Craig M. Gardner
  • Publication number: 20150168367
    Abstract: A method of detecting an explosive material, and an analyzer and computer program products that may perform such methods. A method may include illuminating at least a portion of the material with light, and monitoring the temperature of the illuminated portion. T power or location of the illuminating light may be altered in response to the monitored temperature. Raman spectral data are produced in response to Raman radiation emitted from the portion in response to the light. The composition of the material may be analyzed based on the Raman spectral data or generating an indication to an operator that the material cannot be safely analyzed.
    Type: Application
    Filed: December 18, 2013
    Publication date: June 18, 2015
    Applicant: Thermo Scientific Portable Analytical Instruments Inc.
    Inventors: Craig M. GARDNER, Michael BURKA
  • Publication number: 20140005980
    Abstract: A method, apparatus and computer program product for tagging reference materials of interest in spectroscopic searching applications is presented. A reference list of materials to be considered as part of a final analysis of a spectroscopic analysis of a sample material is generated. A watchlist of at least one material to be retained for a final analysis of the spectroscopic analysis of a sample material is provided. A final analysis of the sample material is preformed using the watchlist of at least one material and the reference list of materials. A determination is then made regarding whether a spectrum of the sample material matches at least one spectrum of materials on the watchlist and on the reference list.
    Type: Application
    Filed: July 2, 2012
    Publication date: January 2, 2014
    Inventors: Robert L. Green, Michael D. Hargreaves, Craig M. Gardner
  • Publication number: 20130197815
    Abstract: A processing application receives peak information associated with multiple known references samples. The processing application partitions a spectrum into multiple different sized range bins such that a substantially equal number of the peaks associated with the known reference samples reside into each of the multiple different sized range bins. To identify a set of candidate reference samples in a library of reference samples that potentially are a good match an unknown sample under test, the processing application compares peaks associated with the unknown sample to the multiple different sized range bins. The greater the number of range bin matches based on peaks in the unknown sample and peaks in a corresponding reference sample, the greater the likelihood that the unknown sample matches the corresponding reference sample.
    Type: Application
    Filed: January 31, 2012
    Publication date: August 1, 2013
    Inventors: Craig M. Gardner, Robert L. Green
  • Patent number: 7761126
    Abstract: The present invention relates generally to a non-invasive method and apparatus for measuring a fluid analyte, particularly relating to glucose or alcohol contained in blood or tissue, utilizing spectroscopic methods. More particularly, the method and apparatus incorporate means for detecting and quantifying changes in the concentration of specific analytes in tissue fluid. Also, the method and apparatus can be used to predict future levels of analyte concentration either in the tissue fluid or in blood in an adjacent vascular system.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: July 20, 2010
    Assignee: Inlight Solutions, Inc.
    Inventors: Craig M. Gardner, Trent D. Ridder, William Gruner
  • Patent number: 7725144
    Abstract: A method of determining disease state in an individual. A portion of the tissue of the individual is illuminated with excitation light, then light emitted by the tissue due to Raman scattering of a chemical with the tissue responsive to the excitation light is detected. The detected light can be combined with a model relating Raman emission with disease state to determine a disease state of the individual. The invention can comprise single wavelength excitation light, scanning of excitation light (illuminating the tissue at a plurality of wavelengths), detection at a single wavelength, scanning of detection wavelengths (detecting emitted light at a plurality of wavelengths), and combinations thereof. The invention also can comprise correction techniques that reduce determination errors due to detection of light other than that from Raman emission of a chemical in the tissue. For example, the reflectance of the tissue can lead to errors if appropriate correction is not employed.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: May 25, 2010
    Assignee: VeraLight, Inc.
    Inventors: Marwood Neal Ediger, Craig M. Gardner, Edward L. Hull
  • Patent number: 7016713
    Abstract: The present invention relates generally to a non-invasive method and apparatus for measuring a fluid analyte, particularly relating to glucose or alcohol contained in blood or tissue, utilizing spectroscopic methods. More particularly, the method and apparatus incorporate means for detecting and quantifying changes in the concentration of specific analytes in tissue fluid. Also, the method and apparatus can be used to predict future levels of analyte concentration either in the tissue fluid or in blood in an adjacent vascular system.
    Type: Grant
    Filed: January 8, 2004
    Date of Patent: March 21, 2006
    Assignee: InLight Solutions, Inc.
    Inventors: Craig M. Gardner, Trent D. Ridder, William Gruner
  • Publication number: 20040167382
    Abstract: The present invention relates generally to a non-invasive method and apparatus for measuring a fluid analyte, particularly relating to glucose or alcohol contained in blood or tissue, utilizing spectroscopic methods. More particularly, the method and apparatus incorporate means for detecting and quantifying changes in the concentration of specific analytes in tissue fluid. Also, the method and apparatus can be used to predict future levels of analyte concentration either in the tissue fluid or in blood in an adjacent vascular system.
    Type: Application
    Filed: January 8, 2004
    Publication date: August 26, 2004
    Inventors: Craig M. Gardner, Trent D. Ridder, William Gruner
  • Publication number: 20030087456
    Abstract: An apparatus and method for infrared spectral analysis of samples to determine if the samples are normal or abnormal or to otherwise classify the sample. More specifically, the apparatus and method classify the sample on the basis of attenuation of infrared radiation at different wavelengths using a within-sample variance model. Further, the method and apparatus can include merging the output of multivariate classification models with the within-sample variance model applied to the infrared spectra sample such that their combined output results in a classification accuracy that is greater than any single model. The invention is useful in classifying, for example, biological samples such as human tissue, including cervical cells.
    Type: Application
    Filed: October 2, 2002
    Publication date: May 8, 2003
    Inventors: Howland D.T. Jones, Craig M. Gardner, Edward L. Hull, Kristin A. Nixon, M. Ries Robinson