Patents by Inventor Craig Morrell

Craig Morrell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antigen-presenting platelets and methods of eliciting an immune response
    Patent number: 9340773
    Abstract: Provided herein are methods of producing an antigen-presenting platelet. Also provided herein are methods of eliciting an immune response in a subject using the antigen-presenting platelets described herein. Also provided are methods of screening for an immune response elicited by an antigen-presenting platelet. Further provided are isolated populations of platelets that present a selected antigen produced by the methods described herein.
    Type: Grant
    Filed: February 22, 2012
    Date of Patent: May 17, 2016
    Assignee: University of Rochester
    Inventor: Craig Morrell
  • ANTIGEN-PRESENTING PLATELETS AND METHODS OF ELICITING AN IMMUNE RESPONSE
    Publication number: 20130330311
    Abstract: Provided herein are methods of producing an antigen-presenting platelet. Also provided herein are methods of eliciting an immune response in a subject using the antigen-presenting platelets described herein. Also provided are methods of screening for an immune response elicited by an antigen-presenting platelet. Further provided are isolated populations of platelets that present a selected antigen produced by the methods described herein.
    Type: Application
    Filed: February 22, 2012
    Publication date: December 12, 2013
    Applicant: UNIVERSITY OF ROCHESTER
    Inventor: Craig Morrell
  • Inhibitors of N-ethylmaleimide sensitive factor
    Patent number: 7910111
    Abstract: Methods and compositions for blocking exocytosis by inhibition of proteins that regulate exocytosis, such as N-ethylmaleimide Sensitive Factor (NSF), are provided. The compositions include multidomain fusion peptides containing a domain that causes the fusion peptide to cross the cellular membrane (e.g. a domain from the TAT protein of HIV) and a domain that inhibits NSF (e.g. a domain of NSF). Administration of the fusion peptide promotes anticoagulation, attenuates thrombosis, and decreases heart attack severity.
    Type: Grant
    Filed: April 15, 2004
    Date of Patent: March 22, 2011
    Assignee: The Johns Hopkins University
    Inventors: Charles Lowenstein, Kenji Matsushita, Craig Morrell
  • METHOD AND SYSTEM FOR ASSESSING RISK
    Publication number: 20090187528
    Abstract: A system and method for assessing a risk outcome that is affected by other risks. The risks and risk outcome are identified, and a relationship among the risks are defined where all of the risks directly or indirectly influence the risk outcome. An influence of each risk on at least one of the other risks or the risk outcome is defined. A portion of the risk relationship hierarchy and a subset of the risks is displayed graphically.
    Type: Application
    Filed: January 20, 2009
    Publication date: July 23, 2009
    Inventors: Robert Craig Morrell, Michael Daniel Ulveling, Antonio Dabraio
  • Inhibitors of n ethymalemide sensitive factor
    Publication number: 20070173441
    Abstract: Methods and compositions for blocking exocytosis by inhibition of proteins that regulate exocytosis, such as N-ethylmaleimide Sensitive Factor (NSF), are provided. The compositions include multidomain fusion peptides containing a domain that causes the fusion peptide to cross the cellular membrane (e.g. a domain from the TAT protein of HIV) and a domain that inhibits NSF (e.g. a domain of NSF). Administration of the fusion peptide promotes anticoagulation, attenuates thrombosis, and decreases heart attack severity.
    Type: Application
    Filed: April 15, 2004
    Publication date: July 26, 2007
    Inventors: Charles Lowenstein, Kenji Matsushita, Craig Morrell