Patents by Inventor Craig Mossman

Craig Mossman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiochromene derivatives as HIF hydroxylase inhibitors
    Patent number: 9149476
    Abstract: The present invention relates to novel compounds, methods, and compositions capable of decreasing HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
    Type: Grant
    Filed: December 24, 2014
    Date of Patent: October 6, 2015
    Assignee: FIBROGEN, INC.
    Inventors: Wen-Bin Ho, Lee A. Flippin, Craig Mossman, Eric D. Turtle, Lee R. Wright
  • THIOCHROMENE DERIVATIVES AS HIF HYDROXYLASE INHIBITORS
    Publication number: 20150182528
    Abstract: The present invention relates to novel compounds, methods, and compositions capable of decreasing HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
    Type: Application
    Filed: December 24, 2014
    Publication date: July 2, 2015
    Inventors: Wen-Bin Ho, Lee A. Flippin, Craig Mossman, Eric D. Turtle, Lee R. Wright
  • Thiochromene derivatives as HIF hydroxylase inhibitors
    Patent number: 8927591
    Abstract: The present invention relates to novel compounds, methods, and compositions capable of decreasing HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
    Type: Grant
    Filed: November 11, 2009
    Date of Patent: January 6, 2015
    Assignee: Fibrogen, Inc.
    Inventors: Wen-Bin Ho, Lee R. Wright, Eric D. Turtle, Craig Mossman, Lee A. Flippin
  • THIOCHROMENE DERIVATIVES AS HIF HYDROXYLASE INHIBITORS
    Publication number: 20110305776
    Abstract: The present invention relates to novel compounds, methods, and compositions capable of decreasing HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
    Type: Application
    Filed: November 11, 2009
    Publication date: December 15, 2011
    Applicant: FibroGen, Inc.
    Inventors: Wen-Bin Ho, Lee A. Flippin, Craig Mossman, Eric D. Turtle, Lee R. Wright
  • SULFONYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS
    Publication number: 20110281879
    Abstract: The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
    Type: Application
    Filed: January 12, 2011
    Publication date: November 17, 2011
    Applicant: ViroBay, Inc.
    Inventor: Craig Mossman
  • Amidino compounds as cysteine protease inhibitors
    Publication number: 20070105892
    Abstract: The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
    Type: Application
    Filed: December 22, 2004
    Publication date: May 10, 2007
    Applicant: AXYS Pharmaceuticals, Inc.
    Inventors: Michael Graupe, Agnes Lau, Jiayao Li, John Link, Craig Mossman, Soon H. Woo, Sheila M. Zipfel
  • Cyanomethyl derivatives as cysteine protease inhibitors
    Publication number: 20060122184
    Abstract: The present invention is directed to cyanomethyl derivatives that are inhibitors of cysteine protease, in particular, cathepsin B, K, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
    Type: Application
    Filed: November 26, 2003
    Publication date: June 8, 2006
    Applicant: AXYS Pharmaceuticals, Inc.
    Inventors: Michael Graupe, Agnes Lau, John Link, Yang Liu, Craig Mossman, John Patterson, Sheila Zipfel
  • Cysteine protease inhibitors
    Publication number: 20050288336
    Abstract: The present invention is directed to compounds that are inhibitors of cysteine protease, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
    Type: Application
    Filed: May 14, 2003
    Publication date: December 29, 2005
    Applicant: AXYS PHARMACEUTICALS, INC.
    Inventors: Michael Graupe, Agnes Lau, John Link, Yang Liu, Craig Mossman, John Patterson, Sheila Zipfel
  • Haloalkyl containing compounds as cysteine protease inhibitors
    Publication number: 20050182096
    Abstract: The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
    Type: Application
    Filed: September 17, 2004
    Publication date: August 18, 2005
    Applicant: AXYS PHARMACEUTICALS, INC.
    Inventors: John Link, Craig Mossman, Soon Woo, Sheila Zipfel