Abstract: A system for providing real-time risk mitigation for an authorization system. The system receives authorization requests from multiple merchants (or their respective acquirers) and processes such requests. Each processed request is then forwarded to its corresponding issuer for further authorization. Each processed request includes an authorization message. The authorization message can include a risk score, a number of reason codes, and a number of condition codes. The use of the risk score, reason codes and condition codes allows issuers to make better informed decisions with respect to providing authorizations.

Abstract: The embodiments provide prodrug compounds of Formulae I-XV. The present disclosure also provides compositions, and their methods of use, where the compositions comprise a prodrug compound of Formulae I-XV that provides controlled release of an opioid. Such compositions can optionally provide a trypsin inhibitor that interacts with the enzyme that mediates the controlled release of an opioid from the prodrug so as to attenuate enzymatic cleavage of the prodrug.

Abstract: The present invention is related to methods and systems for processing search requests and for performing searches over a network. In an embodiment, a recipient designation is received from a user over a network. The designation indicates that future searches performed by the user are to be associated with the recipient (even if the subject matter of the search is not related to the recipient). A search request is received from the user; causing a search to be performed in response to the search request. An identifier corresponding to the recipient is stored in association with an indication regarding the occurrence of the first search request.

Abstract: Methods, systems, and devices are disclosed for using a payment processing network as an authorization engine to access secure physical areas, such as college dormitories, office buildings. A keycard with a cryptogram generator is presented by a user to an access device, and the access device or associated computer sends an access request message formatted like a payment authentication request message to an aggregator/acquirer and payment processing network. The payment processing network validates the cryptogram and returns an access response message, again formatted like a payment authorization response message, indicating that the keycard is authentic. The gate, door, turnstile, or other barrier is then temporarily unlocked to let the user through.

Abstract: The embodiments provide Compound KC-8, N-1-[3-(oxycodone-6-enol-carbonyl-methyl-amino) -2,2-dimethyl-propylamine]-arginine-glycine-malonic acid, or acceptable salts, solvates, and hydrates thereof. The present disclosure also provides compositions, and their methods of use, where the compositions comprise a prodrug, Compound KC-8, that provides controlled release of oxycodone. Such compositions can optionally provide a trypsin inhibitor that interacts with the enzyme that mediates the controlled release of oxycodone from the prodrug so as to attenuate enzymatic cleavage of the prodrug.

Abstract: The GRADUATED SECURITY SEASONING APPARATUSES, METHODS AND SYSTEMS (“GSS”) transform user virtual wallet activity and historical fraud reports via GSS components into transaction authorization triggers generated pursuant to graduated, transaction risk-appropriate, escalated security protocols. In one implementation, the GSS obtains a current transaction request, the request utilizing a user virtual wallet account for payment. The GSS identifies a transaction risk type associated with the request, and calculates a transaction risk level associated with the transaction risk type. Based on the transaction risk level, the GSS selects a security protocol for processing the current transaction request; and provide a security data request in accordance with the selected security protocol.

Abstract: The embodiments provide Compound KC-7, N-1-[(S)-2-(oxycodone-6-enol-carbonyl-methyl-amino)-2-carbonyl-sarcosine-ethyl amine]-arginine-glycine-acetate, or acceptable salts, solvates, and hydrates thereof. The present disclosure also provides compositions, and their methods of use, where the \compositions comprise a prodrug, Compound KC-7, that provides controlled release of oxycodone. Such compositions can optionally provide a trypsin inhibitor that interacts with the enzyme that mediates the controlled release of oxycodone from the prodrug so as to attenuate enzymatic cleavage of the prodrug.

Abstract: The SOCIAL NETWORK PAYMENT AUTHENTICATION APPARATUSES, METHODS AND SYSTEMS (“SNPA”) transform social networking user login inputs via SNPA components into notifications of authenticated purchase transactions. In one embodiment, the SNPA obtains an authentication request for a purchase transaction. The SNPA extracts card account data related to the authentication request, and provides the card account data related to the authentication request to a social networking server. The SNPA also provides an indication for a user to authenticate via logging into a social networking service associated with the social networking server. The SNPA obtains an indication from the social networking server that the user is authenticated. In response to obtaining the indication that the user is authenticated, the SNPA initiates completion of the purchase transaction.

Abstract: Embodiments of the invention is directed to a dynamic network analytics system capable of receiving and analyzing queries sent in data messages from data requesters. The queries contain a request from the data requester as to a risk level associated with an interaction conducted by a user. The dynamic network analytics system can determine an optimized process for determining the risk level of the interaction, based on an analysis of past interactions by the user and past interactions by users similar to the user. The dynamic network analytics system can retrieve data from internal and external data sources to generate a response to the query. The dynamic network analytics system conducts the optimized process and uses the retrieved data to generate risk assessments and risk scores in response to the query from the data requester.

Abstract: The embodiments provide Compound PC-5, [2-((S)-2-malonylamino-6-amino-hexanoyl amino)-ethyl]-ethyl-carbamic acid hydromorphone ester, or acceptable salts, solvates, and hydrates thereof. The present disclosure also provides pharmaceutical compositions, and their methods of use, where the pharmaceutical compositions comprise a prodrug, Compound PC-5, that provides enzymatically-controlled release of hydromorphone, and, optionally, a trypsin inhibitor that interacts with the enzyme that mediates the enzymatically-controlled release of hydromorphone from the prodrug so as to attenuate enzymatic cleavage of the prodrug.

Abstract: The present disclosure provides compositions, and their methods of use, where the compositions comprise a ketone-modified opioid drug, wherein the drug comprises a ketone-modified opioid and a substituent on the opioid that mediates retention of the drug in the peripheral nervous system as opposed to the central nervous system following ingestion by a subject.

Abstract: The present invention is related to methods and systems for processing search requests and for performing searches over a network. In an embodiment, a recipient designation is received from a user over a network. The designation indicates that future searches performed by the user are to be associated with the recipient (even if the subject matter of the search is not related to the recipient). A search request is received from the user; causing a search to be performed in response to the search request. An identifier corresponding to the recipient is stored in association with an indication regarding the occurrence of the first search request.

Abstract: Pharmaceutical compositions and their methods of use are provided, where the pharmaceutical compositions comprise an amphetamine prodrug that provides enzymatically-controlled release of amphetamine or an amphetamine analog. The composition can further comprise an enzyme inhibitor that interacts with the enzyme(s) that mediates the enzymatically-controlled release of amphetamine or the amphetamine analog from the amphetamine prodrug so as to attenuate enzymatic cleavage of the amphetamine prodrug.

Abstract: A transportation system for rider propelled vehicles, zero-emission vehicles, and pedestrians is disclosed. The system includes pathways (517, 317, 717, 519, 119, 319, 719, 919, 523, 123, 323, 723, 923, 525, 325, 725) that are integrated into a building structure (101) or a series of building structures (100, 300, 500, 700, 900) connected by bridges (34, 35, 36, 37, 30, 31, 32, 33) which have an overall downward sloping grade. Elevators (515, 520, 522, 527, 115, 120, 122, 127, 315, 320, 322, 327, 715, 720, 722, 727, 915, 920, 922, 927) are utilized to transport riders, vehicles, and pedestrians to the integrated pathway.

Abstract: The embodiments provide prodrug compounds of Formulae I-XV. The present disclosure also provides compositions, and their methods of use, where the compositions comprise a prodrug compound of Formulae I-XV that provides controlled release of an opioid. Such compositions can optionally provide a trypsin inhibitor that interacts with the enzyme that mediates the controlled release of an opioid from the prodrug so as to attenuate enzymatic cleavage of the prodrug.

Abstract: Some embodiments pertain to a projectile that includes a casing and a plurality of fins which are secured to the casing. Each of the fins is movable between a stowed position and a deployed position. The fins are typically in the stowed position during storage and launch, and move to the deployed position as soon as possible after launch. Each fin includes a first foil that has a first set of openings and a second foil that includes a second set of openings. The first sets of openings in the first foils are aligned with the second sets of openings in the second foils when each of the fins is in the stowed position. The first sets of openings in the first foils are not aligned with the second sets of openings in the second foils when each of the fins is in the deployed position.

Abstract: An aircraft, such as a missile, has control surfaces that have segments that are hinged together. The control surfaces deploy from a closed position, for example with the segments folded against a fuselage, so as to allow for launching from a launch tube. Once the aircraft is launched the control surfaces deploy from the closed position to an open position, with the segments opening up farther from the body or fuselage. In the open position or deployed state the segments may be substantially planar. Locks of the control surfaces may be used to lock the segments in place in the open position. The locks may include hollow sleeves that slide over the control surface segments. The sleeves and the segments may include a protrusions and depressions that engage each other to hold the segments in the open configuration.

Abstract: A method of providing a patient with controlled release of ketone-containing opioid using a prodrug capable, upon enzymatic activation and intramolecular cyclization, of releasing the ketone-containing opioid is disclosed. The disclosure also provides such prodrug compounds and pharmaceutical compositions comprising such compounds. Such pharmaceutical compositions can optionally include an enzyme inhibitor that interacts with the enzyme(s) to mediate the enzymatically-controlled release of the ketone-containing opioid from the prodrug so as to modify enzymatic cleavage of the prodrug. Also included are methods to use such compounds and pharmaceutical compositions.

Abstract: Some embodiments pertain to a projectile that includes a casing and a plurality of fins which are secured to the casing. Each of the fins is movable between a stowed position and a deployed position. The fins are typically in the stowed position during storage and launch, and move to the deployed position as soon as possible after launch. Each fin includes a first foil that has a first set of openings and a second foil that includes a second set of openings. The first sets of openings in the first foils are aligned with the second sets of openings in the second foils when each of the fins is in the stowed position. The first sets of openings in the first foils are not aligned with the second sets of openings in the second foils when each of the fins is in the deployed position.

Abstract: The embodiments provide Compound KC-7, N-1-[(S)-2-(oxycodone-6-enol-carbonyl-methyl-amino)-2-carbonyl-sarcosine-ethyl amine]-arginine-glycine-acetate, or acceptable salts, solvates, and hydrates thereof. The present disclosure also provides compositions, and their methods of use, where the \compositions comprise a prodrug, Compound KC-7, that provides controlled release of oxycodone. Such compositions can optionally provide a trypsin inhibitor that interacts with the enzyme that mediates the controlled release of oxycodone from the prodrug so as to attenuate enzymatic cleavage of the prodrug.