Abstract: Nucleic acid molecules encoding hepatitis B virus (HBV) surface antigens, HBV core antigens, and HBV polymerase antigens, and related combinations, are described. Also described are vectors, such as DNA plasmids or viral vectors, and RNA replicons, expressing the HBV antigens, and pharmaceutical compositions containing the expression vectors. Methods of inducing an immune response against HBV or treating an HBV-induced disease, particularly in individuals having chronic HBV infection, using the pharmaceutical compositions of the invention are also described.

Abstract: A non-linear discussion network comprises methods and technologies that include storing, associating, accessing, and communicating actions; and further displaying discussion sets as well as other information to viewing users.

Abstract: Disclosed herein are fusion antibodies created to provide both an antigen-binding site that targets the CD4 receptor and an antigen-binding site that targets the HIV envelope. The fusion antibodies disclosed herein provide improved potency and breadth against HIV as compared to monospecific antibodies, and additionally provide high barrier against viral resistance. Also disclosed are pharmaceutical formulations and therapeutic methods utilizing such fusion proteins.

Abstract: Disclosed herein are fusion antibodies created to provide both an antigen-binding site that targets the CD4 receptor and an antigen-binding site that targets the HIV envelope. The fusion antibodies disclosed herein provide improved potency and breadth against HIV as compared to monospecific antibodies, and additionally provide high barrier against viral resistance. Also disclosed are pharmaceutical formulations and therapeutic methods utilizing such fusion proteins.

Abstract: A multi-track fastening system having multiple tracks and a central slider or interchange. The central slider has angled openings and paths through which the tracks travel when the central slider is propelled along the tracks. Sliding the central slider along the tracks causes the rows of the tracks to interchange so that a volume of material coupled to the tracks can alternate between two different configurations.

Abstract: Methods and systems for transforming a volume of material into sleeves by means of a transforming fastener. The transforming fastener has multiple tracks, each track having a pair of matable rows. A slider coupled to the rows transforms the volume of material into sleeves when the slider moves along the rows. The slider accomplishes this transformation by fastening one of the pair of rows while simultaneously unfastening another of the pair of rows.

Abstract: A draft barrier system having a sliding fastener that lets a user selectively alternate a volume of material between open and closed formations. When the sliding fastener closes the volume of material into the closed formation, insulation is compressed together to form a seal that helps prevent air from moving between the interior and the environment through the sliding fastener.

Abstract: Methods and systems for transforming a volume of material into pant legs by means of a transforming fastener. The transforming fastener has multiple tracks, each track having a pair of matable rows. A slider coupled to the rows transforms the volume of material into pant legs when the slider moves along the rows. The slider accomplishes this transformation by fastening one of the pair of rows while simultaneously unfastening another of the pair of rows.

Abstract: Methods and systems for transforming a volume of material into pant legs by means of a transforming fastener. The transforming fastener has multiple tracks, each track having a pair of matable rows. A slider coupled to the rows transforms the volume of material into pant legs when the slider moves along the rows. The slider accomplishes this transformation by fastening one of the pair of rows while simultaneously unfastening another of the pair of rows.

Abstract: Methods and systems for transforming a volume of material into sleeves by means of a transforming fastener. The transforming fastener has multiple tracks, each track having a pair of matable rows. A slider coupled to the rows transforms the volume of material into sleeves when the slider moves along the rows. The slider accomplishes this transformation by fastening one of the pair of rows while simultaneously unfastening another of the pair of rows.

Abstract: A multi-track fastening system having multiple tracks and a central slider or interchange. The central slider has angled openings and paths through which the tracks travel when the central slider is propelled along the tracks. Sliding the central slider along the tracks causes the rows of the tracks to interchange so that a volume of material coupled to the tracks can alternate between two different configurations.