Abstract: Containers for the storage of red blood cell compositions are disclosed. The container walls are made of a plastic composition that includes a polymeric material and at least one extractable agent that includes a terephthalate ester in an amount effective to suppress hemolysis in red blood cells.

Abstract: Containers for the storage of red blood cell compositions are disclosed. The container walls are made of a plastic composition that includes a polymeric material and at least one extractable agent that includes a terephthalate ester in an amount effective to suppress hemolysis in red blood cells.

Abstract: A medical solution packaging assembly comprising a medical solution container that houses a medical solution comprising a semi-permeable material including one or more surface that is at least partially permeable to air molecules and has low permeability to vapor molecules of the medical solution, wherein the medical solution container is configured to inflate beyond its original volume. The assembly further comprising a packaging comprising one or more surface within which the solution container resides; a compressing mechanism configured to apply external force onto at least one surface of the medical solution container or limit the volume to which the medical solution container inflates, wherein a volume of air ingress from an external environment of the medical solution container is less than that which would occur without the compressing mechanism.

Abstract: Containers for the storage of red blood cell compositions are disclosed. The container walls are made of a plastic composition that includes a polymeric material and at least one extractable agent that includes a terephthalate ester in an amount effective to suppress hemolysis in red blood cells.

Abstract: A fluid flow circuit assembly for a biological fluid processing device, comprising a PVC tubing comprising a polymeric plasticizer and/or a high molecular weight plasticizer having a molecular weight of 540 g/mol or more. The fluid flow circuit assembly also comprises a medical device component comprising a bond surface to which the PVC tubing is bonded by a solvent, wherein the bond surface comprises a polyester elastomer, plasticized PVC, and/or a polycarbonate.

Abstract: A container for blood or a blood component is provided, the container comprising one or more container walls defining an interior chamber, the container walls comprising one or more layers, the layers comprising or consisting of a composition comprising one or more polymeric materials and at least one extractable agent selected from the group consisting of a terephthalate ester, a cyclohexane dicarboxylic acid ester, a citrate ester, and a polyol ester, wherein the container further comprises one or more additional components, wherein the container comprises less than about 3% (w/w) of di-2-ethylhexyl phthalate (DEHP), preferably wherein the container comprises less than about 3% (w/w) of phthalates. Thereby, improved blood products are provided in which the DEHP or overall phthalate content is reduced.

Abstract: Containers and components thereof for use in the medical industry and methods to manufacture the same are described. An example tab for use with a medical container includes opposing sheets sealed to define an open ended chamber into which a port is to be at least partially positioned. The port is to enable access to the medical container. The tab includes a tear seal defined by each of the opposing sheets and a first guide positioned on a first side of each of the tear seals. The tab includes a second guide positioned on a second side of each of the tear seals, wherein the first and second guides are to enable a tear to propagate substantially between the guides and adjacent the tear seals.

Abstract: A method is provided for making a tubing, which includes forming a generally tubular inner layer by flowing a first material through an extrusion assembly. At least one non-tubular segment is formed along the length of the tubing by flowing a second material through the extrusion assembly. A generally tubular outer layer coaxial with the inner layer is formed by flowing a third material through the extrusion assembly. The segment is positioned between the inner and outer layers and oriented non-tangentially with an interface between the inner and outer layers. The resulting tubing, which may be suitable for medical applications, may have kink-resistant properties.

Abstract: A medical solution packaging assembly comprising a medical solution container that houses a medical solution comprising a semi-permeable material including one or more surface that is at least partially permeable to air molecules and has low permeability to vapor molecules of the medical solution, wherein the medical solution container is configured to inflate beyond its original volume. The assembly further comprising a packaging comprising one or more surface within which the solution container resides; a compressing mechanism configured to apply external force onto at least one surface of the medical solution container or limit the volume to which the medical solution container inflates, wherein a volume of air ingress from an external environment of the medical solution container is less than that which would occur without the compressing mechanism.

Abstract: A citrate detector is provided for use in combination with a blood processing system and replacement fluid tubing or conduit of a disposable set. The citrate detector comprises a light source and a light detector. The light source is configured to emit a light having a wavelength absorbed by citrate, but at least partially transmitted by the replacement fluid conduit of the disposable set. The light detector is configured to receive at least a portion of the light from the light source and generate a signal indicative of the presence or absence of citrate in the replacement fluid conduit based, at least in part, on the amount of light received from the light source. A blood processing system incorporating such a citrate detector may include a flow detector for determining whether fluid is present in the conduit prior to checking for the presence of citrate.

Abstract: Sheets for use with medical containers are described. An example sheet for use with medical containers includes a plurality of layers. At least one of the layers includes polyolefin and the plurality of the layers comprises approximately less than 15% of at least one of a plasticizer or a low molecular weight material that is to decrease a rate of hemolysis when exposed to a blood component. At least one of the plurality of layers being modified to enable autoclavability and radio frequency sealability.

Abstract: A fluid identification assembly is provided to determine the presence or absence of multiple components within a fluid in a conduit. The assembly includes a light source and a light detector positioned to receive a portion of light from the light source reflected by the conduit and fluid. A dual-band bandpass filter may be associated with the light detector to allow multiple wavelengths of light to be monitored, thereby monitoring the composition of the fluid based on the amount of light of each wavelength absorbed by the fluid. Rather than a dual-band bandpass filter, a second light detector may be provided, along with a beam splitter to separate light from a single source for receipt of light of different wavelengths by the light detectors. The dual-band bandpass filter may also be replaced by a second light source and detector pair for analyzing fluid using multiple wavelengths of light.

Abstract: A citrate detector is provided for use in combination with a blood processing system and replacement fluid tubing or conduit of a disposable set. The citrate detector comprises a light source and a light detector. The light source is configured to emit a light having a wavelength absorbed by citrate, but at least partially transmitted by the replacement fluid conduit of the disposable set. The light detector is configured to receive at least a portion of the light from the light source and generate a signal indicative of the presence or absence of citrate in the replacement fluid conduit based, at least in part, on the amount of light received from the light source. A blood processing system incorporating such a citrate detector may include a flow detector for determining whether fluid is present in the conduit prior to checking for the presence of citrate.

Abstract: Containers for the storage of red blood cell compositions are disclosed. The container walls are made of a plastic composition that includes a polymeric material and at least one extractable agent that includes a terephthalate ester in an amount effective to suppress hemolysis in red blood cells.

Abstract: A citrate detector is provided for use in combination with a blood processing system and replacement fluid tubing or conduit of a disposable set. The citrate detector comprises a light source and a light detector. The light source is configured to emit a light having a wavelength absorbed by citrate, but at least partially transmitted by the replacement fluid conduit of the disposable set. The light detector is configured to receive at least a portion of the light from the light source and generate a signal indicative of the presence or absence of citrate in the replacement fluid conduit based, at least in part, on the amount of light received from the light source. A blood processing system incorporating such a citrate detector may include a flow detector for determining whether fluid is present in the conduit prior to checking for the presence of citrate.

Abstract: A citrate detector is provided for use in combination with a blood processing system and replacement fluid tubing or conduit of a disposable set. The citrate detector comprises a light source and a light detector. The light source is configured to emit a light having a wavelength absorbed by citrate, but at least partially transmitted by the replacement fluid conduit of the disposable set. The light detector is configured to receive at least a portion of the light from the light source and generate a signal indicative of the presence or absence of citrate in the replacement fluid conduit based, at least in part, on the amount of light received from the light source. A blood processing system incorporating such a citrate detector may include a flow detector for determining whether fluid is present in the conduit prior to checking for the presence of citrate.

Abstract: Containers and components thereof for use in the medical industry and methods to manufacture the same are described. An example tab for use with a medical container includes opposing sheets sealed to define an open ended chamber into which a port is to be at least partially positioned. The port is to enable access to the medical container. The tab includes a tear seal defined by each of the opposing sheets and a first guide positioned on a first side of each of the tear seals. The tab includes a second guide positioned on a second side of each of the tear seals, wherein the first and second guides are to enable a tear to propagate substantially between the guides and adjacent the tear seals.

Abstract: A system and method for automatically delivering an infusate to a patient is disclosed. The system includes an infusion set and an infusion device. A signaling component disposed on an infusion set component identifies an administration protocol for the infusion set. A detection device operatively connected to the infusion device detects the signaling component and identifies the administration protocol. The infusion device is then configured to operate according to the administration protocol.

Abstract: A blood donor tube sealing apparatus includes a housing configured to house an electronic circuit configured to provide a radio frequency signal. The sealing apparatus further includes a sealing device coupled to the housing. The sealing device includes a movable sealing head and at least one movable tube support. The movable sealing head and movable tube support are configured to be moved into contact with a blood donor tube. The movable sealing head is powered by the radio frequency signal to seal the blood donor tube.

Abstract: A flexible, kink-resistant medical tube and a method and apparatus for making the same are provided. The tube includes a body having a first end, a second end, an outer surface and an inner surface. The tube includes a lumen defined by the inner surface of the body and extending between the first end and the second end. The tube also includes a helical structure within in the body.