Abstract: An optical sensor system may include optical fibers having at least one corresponding optical sensing element configured to reflect light; a laser configured to output light of a discrete wavelength and to change the discrete wavelength through a sequence; an optical network connecting the laser to the optical fibers, and configured to split the output light so that a split portion of the output light is transmitted through an optical fiber of the optical fibers to the at least one corresponding optical sensing element which may reflect at least a portion of the split portion; an optical sensor configured to obtain information about of the reflected light and to output data corresponding to the information about the reflected light; and a processor configured to: obtain, from the optical sensor, the data corresponding to the information about the reflected light in correspondence with discrete wavelengths of the sequence.

Abstract: The present invention relates to a method of determining the total organic carbon content (TOC) of a purified water stream in a water purification apparatus having at least a first pump, a first conductivity sensor, an oxidiser, and an oxidiser recirculation circuit having a dedicated second pump, the method comprising at least the steps of: (a) using the first pump to pass a water supply stream through the water purification apparatus, including through the first conductivity sensor and the oxidiser, to provide a purified water stream available for dispense; (b) using the first conductivity sensor to measure a first conductivity value of the water supply stream prior to the oxidiser; (c) stopping the first pump; (d) using the second pump in the oxidiser recirculation circuit to recirculate the water in the oxidiser only through the first conductivity sensor and the oxidiser a plurality of times, (e) using the first conductivity sensor to measure a second conductivity value of the recirculated water; and (

Abstract: The present invention is directed to genome editing systems, reagents and methods for immunooncology.

Abstract: The present invention is directed to genome editing systems, reagents and methods for immunooncology.

Abstract: In accordance with various aspects of the invention, a recall transaction is issued if a tag filter entry needs to be freed up for an incoming transaction. Directory entries chosen for a recall transaction are pushed into a fully associative structure called victim buffer. If this structure gets full, then an entry is selected from entries inside the victim buffer for the recall.

Abstract: A method of joining a razor blade to a blade support to form a razor blade assembly, the method including: directing a laser beam having an adjustable power output at an upper surface of the razor blade; and while advancing the laser beam along the razor blade: a) applying the laser beam at a first power output to the razor blade; b) reducing the first power output of the laser beam to a second power output; and c) applying the laser beam at the second power output to the razor to form a weld area joining the razor blade to the blade support. The weld area may be elongated and may include (i) a ratio of depth:width that is greater than about 2:1, and/or (ii) a ratio of length:width that is greater than about 5:1.

Abstract: A modular test instrument for performing tests and measurements in a network is disclosed. The modular test instrument may include a modular processing unit comprising a processor and memory, the modular processing unit connectable to at least one modular test unit or modular test subunit. The modular test instrument may also include a modular display unit connectable to the modular processing unit or the modular test unit. Display modularity may enable quick and cost-efficient display replacement when damage, malfunction, or failure is incurred. Furthermore, the modular test instrument may include an additional modular test subunit connectable to at least one of the modular processing unit or the modular test unit.

Abstract: A cell site test tool provides field technicians with resources to support multiple aspects of cell site testing. The cell site test tool includes multiple, integrated and removably connectable modules such as a base module, a user interface module, and a battery module. Additional modules include a CPRI module to provide Common Public Radio Interface testing, an OTDR module to provide dedicated Optical Time-Domain Reflectometer testing, a CAA module to provide Cable Antenna Analysis testing, a fiber inspection module to visually inspect optical fiber, and an SA/CPRI module to provide Radio Frequency over Common Public Radio Interface testing.

Abstract: The present invention is directed to genome editing systems, reagents and methods for the treatment of hemoglobinopathies.

Abstract: A cell site test tool provides field technicians with resources to support multiple aspects of cell site testing. The cell site test tool includes multiple, integrated and removably connectable modules such as a base module, a user interface module, and a battery module. Additional modules include a CPRI module to provide Common Public Radio Interface testing, an OTDR module to provide dedicated Optical Time-Domain Reflectometer testing, a CAA module to provide Cable Antenna Analysis testing, a fiber inspection module to visually inspect optical fiber, and an SA/CPRI module to provide Radio Frequency over Common Public Radio Interface testing.

Abstract: A modular test instrument for performing tests and measurements in a network is disclosed. The modular test instrument may include a modular processing unit comprising a processor and memory, the modular processing unit connectable to at least one modular test unit or modular test subunit. The modular test instrument may also include a modular display unit connectable to the modular processing unit or the modular test unit. Display modularity may enable quick and cost-efficient display replacement when damage, malfunction, or failure is incurred. Furthermore, the modular test instrument may include an additional modular test subunit connectable to at least one of the modular processing unit or the modular test unit.

Abstract: Disclosed are apparatuses, systems, methods, and devices for generating high-pressure gas such as hydrogen and oxygen. In one aspect, an apparatus is disclosed. The apparatus includes a reactor which includes a pressure vessel containing a metal compound configured to react with a liquid to generate the high-pressure gas when the liquid is available in the vessel. The reactor includes an outlet configured to pass the generated high-pressure gas out of the vessel. The apparatus also includes a receiver configured to store the generated high-pressure gas generated in the vessel and passed to a receiver via the outlet or passed directly to fuel cell or vehicle tank.

Abstract: The present invention is directed to genome editing systems, reagents and methods for the treatment of hemoglobinopathies.

Abstract: In accordance with various aspects of the invention, a recall transaction is issued if a tag filter entry needs to be freed up for an incoming transaction. Directory entries chosen for a recall transaction are pushed into a fully associative structure called victim buffer. If this structure gets full, then an entry is selected from entries inside the victim buffer for the recall.

Abstract: A modular test instrument for performing tests and measurements in a network is disclosed. The modular test instrument may include a modular processing unit comprising a processor and memory, the modular processing unit connectable to at least one modular test unit or modular test subunit. The modular test instrument may also include a modular display unit connectable to the modular processing unit or the modular test unit. Display modularity may enable quick and cost-efficient display replacement when damage, malfunction, or failure is incurred. Furthermore, the modular test instrument may include an additional modular test subunit connectable to at least one of the modular processing unit or the modular test unit.

Abstract: Compounds of general formula (I): wherein R1, R2, R3, R4, R5a, R5b X1, X2, Z and Y are as defined herein are positive modulators of the calcium-activated chloride channel (CaCC), TMEM16A. The compounds are useful for treating diseases and conditions affected by modulation of TMEM16A, particularly respiratory diseases and conditions.

Abstract: In accordance with various aspects of the invention, a recall transaction is issued if a tag filter entry needs to be freed up for an incoming transaction. Directory entries chosen for a recall transaction are pushed into a fully associative structure called victim buffer. If this structure gets full, then an entry is selected from entries inside the victim buffer for the recall.

Abstract: A slope sensitive pitch adjustor for a bicycle seat includes a rotatable seat support, a gravity sensor mounted thereto, a means for rotating the rotatable seat support, and an automated controller configured to drive the rotating means in response to an acceleration signal received from the gravity sensor. The automated controller stores data representing an initial condition of a pitch angle of the rotatable seat support with respect to horizontal and executes a control algorithm to maintain the initial condition when the bicycle is ridden over changing gradients.

Abstract: A razor blade assembly including: a razor blade; a blade support; and one or more weld areas joining the razor blade to the blade support, each weld area having a length and a width, in which the width is about 0.05 mm to about 0.15 mm. Also provided is a razor blade assembly including: a razor blade; a blade support; and one or more weld areas joining the razor blade to the blade support, each weld area including a depth and a width, in which the depth is about 0.10 mm to about 0.20 mm.