Patents by Inventor Craig Stolarczyk

Craig Stolarczyk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • APPARATUS FOR BIOMOLECULE ASSAY
    Publication number: 20240125795
    Abstract: Disclosed herein are methods for identifying physicochemical properties associated with protein corona formation at the level of proteins and NP-functionalization. Further disclosed herein are compositions comprising combinations of particles configured for low abundance protein collection and deep proteomic analysis.
    Type: Application
    Filed: February 25, 2022
    Publication date: April 18, 2024
    Inventors: Daniel Hornburg, Craig Stolarczyk, Behzad Tangeysh, Asim Siddiqui, Tristan Brown, Shadi Roshdiferdosi, Martin Goldberg, Moaraj HASAN
  • COMPOSITIONS, METHODS AND SYSTEMS FOR PROTEIN CORONA ANALYSIS AND USES THEREOF
    Publication number: 20230417744
    Abstract: Compositions, methods, and systems for analyzing the protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic targets.
    Type: Application
    Filed: September 1, 2023
    Publication date: December 28, 2023
    Inventors: Hongwei XIA, Lyndal HESTERBERG, Michael FIGA, Xiaoyan ZHAO, Gregory TROIANO, William MANNING, John BLUME, Omid FAROKHZAD, Matthew MCLEAN, Craig STOLARCZYK, Marwin KO, Theodore Platt
  • Conjugated Polymeric Particle and Method of Making Same
    Publication number: 20230407391
    Abstract: A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent.
    Type: Application
    Filed: June 14, 2023
    Publication date: December 21, 2023
    Inventors: Steven M. MENCHEN, Alan BLANCHARD, Luisa ANDRUZZI, Shaheer KHAN, Dmitriy GREMYACHINSKIY, Alfred LUI, Craig STOLARCZYK, Tanya SOKOLSKY, Prasanna Krishnan THWAR
  • PARTICLES AND METHODS OF ASSAYING
    Publication number: 20230324401
    Abstract: Disclosed herein are particles and methods of using said particles in assays for detection of biomolecules in a sample. Various methods of the present disclosure utilize particles for biomolecule adsorption. In some aspects, the present disclosure provides methods which utilize multiple particle concentrations to differentially fractionate biological samples. In further aspects, the present disclosure provides methods which utilize low particle concentrations to enhance adsorbed biomolecule diversity.
    Type: Application
    Filed: July 19, 2021
    Publication date: October 12, 2023
    Inventors: Omid C. FAROKHZAD, Craig STOLARCZYK, John E. BLUME, Xiaoyan ZHAO, Martin GOLDBERG, Michael FIGA, Asim SIDDIQUI, Daniel HORNBURG, Damian HARRIS, Philip MA, Theodore PLATT, Shadi ROSHDIFERDOSI
  • Conjugated polymeric particle and method of making same
    Patent number: 11702696
    Abstract: A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent.
    Type: Grant
    Filed: July 24, 2020
    Date of Patent: July 18, 2023
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Steven M. Menchen, Alan Blanchard, Luisa Andruzzi, Shaheer Khan, Dmitriy Gremyachinskiy, Alfred Lui, Craig Stolarczyk, Tanya Sokolsky, Prasanna Krishnan Thwar
  • SYSTEMS FOR PROTEIN CORONA ANALYSIS
    Publication number: 20220334123
    Abstract: Described herein are methods and systems for identifying protein-protein interactions using particle panels and protein corona formation. Also disclosed herein are systems and methods for enrichment analysis between protein annotations and particle biophysicochemical properties.
    Type: Application
    Filed: April 29, 2022
    Publication date: October 20, 2022
    Inventors: Omid FAROKHZAD, Asim SIDDIQUI, Margaret DONOVAN, John E. BLUME, Craig STOLARCZYK
  • Compositions, methods and systems for protein corona analysis and uses thereof
    Patent number: 11428688
    Abstract: Compositions, methods, and systems for analyzing the protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic targets.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: August 30, 2022
    Assignee: SEER, INC.
    Inventors: Hongwei Xia, Lyndal Hesterberg, Michael Figa, Xiaoyan Zhao, Gregory Troiano, William Manning, John Blume, Omid Farokhzad, Matthew McLean, Craig Stolarczyk, Marwin Ko, Theodore Platt
  • COMPOSITIONS, METHODS AND SYSTEMS FOR PROTEIN CORONA ANALYSIS AND USES THEREOF
    Publication number: 20210285957
    Abstract: Compositions, methods, and systems for analyzing the protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic targets.
    Type: Application
    Filed: March 29, 2021
    Publication date: September 16, 2021
    Inventors: Hongwei XIA, Lyndal HESTERBERG, Michael FIGA, Xiaoyan ZHAO, Gregory TROIANO, William MANNING, John BLUME, Omid FAROKHZAD, Matthew MCLEAN, Craig STOLARCZYK, Marwin KO, Theodore Platt
  • COMPOSITIONS, METHODS AND SYSTEMS FOR PROTEIN CORONA ANALYSIS AND USES THEREOF
    Publication number: 20210215685
    Abstract: Compositions, methods, and systems for analyzing the protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic targets.
    Type: Application
    Filed: March 29, 2021
    Publication date: July 15, 2021
    Inventors: Hongwei XIA, Lyndal HESTERBERG, Michael FIGA, Xiaoyan ZHAO, Gregory TROIANO, William MANNING, John BLUME, Omid FAROKHZAD, Matthew MCLEAN, Craig STOLARCZYK, Marwin KO, Theodore Platt
  • CONJUGATED POLYMERIC PARTICLE AND METHOD OF MAKING SAME
    Publication number: 20200354789
    Abstract: A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent.
    Type: Application
    Filed: July 24, 2020
    Publication date: November 12, 2020
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Steven M. MENCHEN, Alan BLANCHARD, Luisa ANDRUZZI, Shaheer KHAN, Dmitriy GREMYACHINSKIY, Alfred LUI, Craig STOLARCZYK, Tanya SOKOLSKY, Prasanna Krishnan THWAR
  • Conjugated polymeric particle and method of making same
    Patent number: 10724094
    Abstract: A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: July 28, 2020
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Steven M. Menchen, Alan Blanchard, Luisa Andruzzi, Shaheer H. Khan, Dmitriy Gremyachinskiy, Alfred Lui, Craig Stolarczyk, Tanya Sokolsky, Prasanna Krishnan Thwar
  • CONJUGATED POLYMERIC PARTICLE AND METHOD OF MAKING SAME
    Publication number: 20180223359
    Abstract: A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent.
    Type: Application
    Filed: April 4, 2018
    Publication date: August 9, 2018
    Inventors: Steven M. MENCHEN, Alan BLANCHARD, Luisa ANDRUZZI, Shaheer H. KHAN, Dmitriy GREMYACHINSKIY, Alfred LUI, Craig STOLARCZYK, Tanya SOKOLSKY, Prasanna Krishnan THWAR
  • Conjugated polymeric particle and method of making same
    Patent number: 9938577
    Abstract: A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: April 10, 2018
    Assignee: Life Technologies Corporation
    Inventors: Steven M. Menchen, Alan Blanchard, Luisa Andruzzi, Shaheer H. Khan, Dmitriy Gremyachinskiy, Alfred Lui, Craig Stolarczyk, Tanya Sokolsky, Prasanna Krishnan Thwar
  • Conjugated Polymeric Particle and Method of Making Same
    Publication number: 20160002723
    Abstract: A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent.
    Type: Application
    Filed: September 16, 2015
    Publication date: January 7, 2016
    Inventors: Steven M. MENCHEN, Alan Blanchard, Luisa Andruzzi, Shaheer H. Khan, Dmitriy Gremyachinskiy, Alfred Lui, Craig Stolarczyk, Tanya Sokolsky, Prasanna Krishnan Thwar
  • Conjugated polymeric particle and method of making same
    Patent number: 9139667
    Abstract: A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent.
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: September 22, 2015
    Assignee: Life Technologies Corporation
    Inventors: Steven Menchen, Alan Blanchard, Luisa Andruzzi, Shaheer Khan, Dmitriy Gremyachinskiy, Alfred Lui, Craig Stolarczyk, Tanya Sokolsky, Prasanna Krishnan Thwar