Patents by Inventor Craig Struble

Craig Struble has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESSES FOR CALCULATING PHASED FETAL GENOMIC SEQUENCES
    Publication number: 20130311107
    Abstract: The present invention provides processes for calculating phased genomic sequences of the fetal genome using fetal DNA obtained from a maternal sample. The processes and systems of the present invention utilize novel technological and computational approaches to detect fetal genomic sequences and determine the phased heritable genomic sequences. The invention could be used, e.g., to identify in utero deleterious mutations carried by the parents and inherited by a fetus within a particular heritable genomic region.
    Type: Application
    Filed: May 20, 2013
    Publication date: November 21, 2013
    Applicant: Ariosa Diagnostics, Inc.
    Inventors: John Stuelpnagel, Craig Struble, Eric Wang
  • STATISTICAL ANALYSIS FOR NON-INVASIVE SEX CHROMOSOME ANEUPLOIDY DETERMINATION
    Publication number: 20130275103
    Abstract: The present invention provides methods for non-invasive determination of X and/or Y chromosomal abnormalities indicative of aneuploidy or sex mosaicisms in a maternal sample by detecting and determining the relative contribution of genetic sequences from the X chromosome and/or the Y chromosome in the maternal sample.
    Type: Application
    Filed: June 13, 2013
    Publication date: October 17, 2013
    Inventors: Craig Struble, Arnold Oliphant, Eric Wang
  • DETERMINATION OF COPY NUMBER VARIATIONS USING BINOMIAL PROBABILITY CALCULATIONS
    Publication number: 20130060483
    Abstract: This invention relates to a binomial calculation of copy number of data obtained from a mixed sample having a first source and a second source.
    Type: Application
    Filed: September 6, 2012
    Publication date: March 7, 2013
    Inventors: Craig Struble, John Stuelpnagel
  • DETERMINATION OF SOURCE CONTRIBUTIONS USING BINOMIAL PROBABILITY CALCULATIONS
    Publication number: 20130024127
    Abstract: This invention relates to calculation of percent contribution of data from a major source and a minor source in a sample.
    Type: Application
    Filed: July 19, 2012
    Publication date: January 24, 2013
    Inventors: John Stuelpnagel, Craig Struble
  • RISK CALCULATION FOR EVALUATION OF FETAL ANEUPLOIDY
    Publication number: 20120191358
    Abstract: The present invention provides processes for determining accurate risk probabilities for fetal aneuploidies. Specifically, the invention provides non-invasive evaluation of genomic variations through chromosome-selective sequencing and non-host fraction data analysis of maternal samples.
    Type: Application
    Filed: December 28, 2011
    Publication date: July 26, 2012
    Applicant: Aria Diagnostics, Inc.
    Inventors: Arnold Oliphant, Andrew Sparks, Eric Wang, Craig Struble
  • RISK CALCULATION FOR EVALUATION OF FETAL ANEUPLOIDY
    Publication number: 20120190557
    Abstract: The present invention provides processes for determining accurate risk probabilities for chromosome dosage abnormalities. Specifically, the invention provides non-invasive evaluation of genomic variations through chromosome-selective sequencing and non-host fraction data analysis of maternal samples.
    Type: Application
    Filed: December 9, 2011
    Publication date: July 26, 2012
    Applicant: Aria Diagnostics, Inc.
    Inventors: Arnold Oliphant, Andrew Sparks, Eric Wang, Craig Struble
  • ENHANCED RISK PROBABILITIES USING BIOMOLECULE ESTIMATIONS
    Publication number: 20120190018
    Abstract: The present invention provides processes for determining more accurate risk probabilities for medical conditions. The risk probabilities of the presence or absence of a medical condition are calculated using frequency data from selected biomolecules and biomolecule source contribution of at least one source in a mixed sample.
    Type: Application
    Filed: October 15, 2011
    Publication date: July 26, 2012
    Applicant: Tandem Diagnostics, Inc.
    Inventors: Craig Struble, Eric Wang, Andrew Sparks, Arnold Oliphant
  • ASSAY SYSTEMS FOR DETERMINATION OF FETAL COPY NUMBER VARIATION
    Publication number: 20120191367
    Abstract: The present invention provides processes for determining accurate risk probabilities for chromosome dosage abnormalities. Specifically, the invention provides non-invasive evaluation of genomic variations through chromosome-selective sequencing and non-host fraction data analysis of maternal samples.
    Type: Application
    Filed: March 21, 2012
    Publication date: July 26, 2012
    Inventors: John Stuelpnagel, Ken Song, Arnold Oliphant, Craig Struble
  • ASSAY SYSTEMS FOR DETERMINATION OF SOURCE CONTRIBUTION IN A SAMPLE
    Publication number: 20120034685
    Abstract: The present invention provides assay systems and methods for detection of copy number variation at one or more loci and polymorphism detection at one or more loci in a mixed sample from an individual.
    Type: Application
    Filed: August 8, 2011
    Publication date: February 9, 2012
    Applicant: TANDEM DIAGNOSTICS, INC.
    Inventors: Andrew Sparks, Craig Struble, Eric Wang, Arnold Oliphant