Patents by Inventor Craig Takeuchi

Craig Takeuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • c-MET MODULATORS AND METHOD OF USE
    Publication number: 20070244116
    Abstract: The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides quinazolines and quinolines which inhibit, regulate, and/or modulate kinase receptor, particularly c-Met, KDF, c-Kit, flt-3 and flt-4, signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.
    Type: Application
    Filed: May 24, 2007
    Publication date: October 18, 2007
    Applicant: EXELIXIS, INC.
    Inventors: LYNNE BANNEN, Diva Chan, Jeff Chen, Lisa Dalrymple, Timothy Forsyth, Tai Huynh, Vasu Jammalamadaka, Richard Khoury, James Leahy, Morrison Mac, Grace Mann, Larry Mann, John Nuss, Jason Parks, Craig Takeuchi, Yong Wang, Wei Xu
  • C-MET MODULATORS AND METHOD OF USE
    Publication number: 20070225307
    Abstract: The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides quinazolines and quinolines which inhibit, regulate, and/or modulate kinase receptor, particularly c-Met, KDF, c-Kit, flt-3 and flt-4, signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.
    Type: Application
    Filed: May 24, 2007
    Publication date: September 27, 2007
    Applicant: EXELIXIS, INC.
    Inventors: Lynne Bannen, Diva Chan, Jeff Chen, Lisa Dalrymple, Timothy Forsyth, Tai Huynh, Vasu Jammalamadaka, Richard Khoury, James Leahy, Morrison Mac, Grace Mann, Larry Mann, John Nuss, Jason Parks, Craig Takeuchi, Yong Wang, Wie Xu
  • c-Met modulators and methods of use
    Publication number: 20070054928
    Abstract: The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides quinazolines and quinolines which inhibit, regulate and/or modulate kinase receptor, particularly c-Met, KDR, c-Kit, flt-3 and flt-4, signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.
    Type: Application
    Filed: October 26, 2006
    Publication date: March 8, 2007
    Applicant: EXELIXIS, INC.
    Inventors: Lynne Bannen, Diva Chan, Jeff Chen, Lisa Dalrymple, Timothy Forsyth, Tai Huynh, Vasu Jammalamadaka, Richard Khoury, James Leahy, Morrison Mac, Grace Mann, Larry Mann, John Nuss, Jason Parks, Craig Takeuchi, Yong Wang, Wei Xu
  • Tie-2 modulators and methods of use
    Publication number: 20060293342
    Abstract: The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases, particularly Tie-2. Methods of using the compounds and pharmaceutical compositions thereof to treat kinase-dependent diseases and conditions are also an aspect of the invention.
    Type: Application
    Filed: April 8, 2004
    Publication date: December 28, 2006
    Applicant: EXELIXIS, INC.
    Inventors: Jeff Chen, Lisa Dalrymple, Sergey Epshteyn, Timothy Forsyth, Tai Huynh, James Leahy, Brian Ridgway, Grace Mann, Larry Mann, Craig Takeuchi, Joan Sangalang
  • Protein kinase modulators and methods of use
    Publication number: 20060211709
    Abstract: Substituted aryl 1,4-pyrazine derivatives and their use in treating anxiety disorders, depression and stress related disorders are disclosed.
    Type: Application
    Filed: May 2, 2003
    Publication date: September 21, 2006
    Inventors: Chris Buhr, Tae-Gon Baik, Sunghoon Ma, Zerom Tesfai, Longcheng Wang, Erick Co, Sergey Epshteyn, Abigail Kennedy, Baili Chen, Larisa Dubenko, Neel Anand, Tsze Tsang, John Nuss, Csabaj Peto, Kenneth Rice, Mohamed Ibrahim, Xian Shi, James Leahy, Jeff Chen, Lisa Dalrymple, Timothy Forsyth, Tai Huynh, Grace Mann, Larry Mann, Craig Takeuchi