Abstract: The present disclosure is directed to systems and methods for transparent Provider Backbone Bridge forwarding of MACsec key exchanges over public Ethernet provider backbones. The method includes the steps of receiving, at a first PBB device, an Ethernet frame from a first edge router for transmission to a second edge router via a MACsec connection, the Ethernet frame comprising a plurality of fields; performing a lookup of one or more fields of the plurality of fields to determine a match with one or more pre-defined values; determining that the one or more fields of the Ethernet frame match the one or more pre-defined values; rewriting the one or more fields of the Ethernet frame to one or more open values operable to allow the Ethernet frame to be transmitted to a next hop device; and transmitting the Ethernet frame to the next hop device.

Abstract: Various analyte sensing apparatuses and associated housings are provided. Some apparatuses comprise one or more caps. Some apparatuses comprise a two-part adhesive patch. Some apparatuses comprise one or more sensor bends configured to locate and/or hold a sensor in place during mounting. Some apparatuses utilize one or more dams and/or wells to retain epoxy for securing a sensor. Some apparatuses utilize a pocket and one or more adjacent areas and various transitions for preventing epoxy from wicking to undesired areas of the apparatus. Some apparatuses include heat-sealable thermoplastic elastomers for welding a cap to the apparatus. Related methods of fabricating such apparatuses and/or housings are also provided.

Abstract: The present invention relates to novel alpha5 subunit-selective negative allosteric modulators of GABAA receptors that have been deuterated to improve their medicinal properties by prolonging their half-lives, rendering them useful as fast-acting pharmaceutical treatments for depression related disorders.

Abstract: Various analyte sensing apparatuses and associated housings are provided. Some apparatuses comprise one or more caps. Some apparatuses comprise a two-part adhesive patch. Some apparatuses comprise one or more sensor bends configured to locate and/or hold a sensor in place during mounting. Some apparatuses utilize one or more dams and/or wells to retain epoxy for securing a sensor. Some apparatuses utilize a pocket and one or more adjacent areas and various transitions for preventing epoxy from wicking to undesired areas of the apparatus. Some apparatuses include heat-sealable thermoplastic elastomers for welding a cap to the apparatus. Related methods of fabricating such apparatuses and/or housings are also provided.

Abstract: Data-stream bridging for sensor transitions is described. A first data stream of glucose measurements is received from a first glucose sensor worn by a user. A termination event for the first glucose sensor is detected when production and/or communication of the first glucose measurements via the first data stream ceases. Next, a second data stream of glucose measurements is received from a second glucose sensor worn by the user that replaces the first glucose sensor. During a warmup period for the second glucose sensor, estimated glucose values are output for the user based on both the first data stream of glucose measurements received from the first glucose sensor prior to the termination event and the second data stream of glucose measurements received from the second glucose sensor.

Abstract: A network controller is configured to control a plurality of network devices in a network. The network controller generates one or more commands that are configured to inject a failure to propagate through two or more network devices in the network. The network controller provides the one or more commands to at least one of the two or more network devices to initiate the failure. The one or more commands cause the failure cause the two or more network devices to collect and propagate telemetry data, on a hop-by-hop basis. The network controller obtains the telemetry data collected from the two or more network devices, and analyzes the telemetry data to determine an impact in the network of the failure propagated through the two or more network devices.

Abstract: Various analyte sensing apparatuses and associated housings are provided. Some apparatuses comprise one or more caps. Some apparatuses comprise a two-part adhesive patch. Some apparatuses comprise one or more sensor bends configured to locate and/or hold a sensor in place during mounting. Some apparatuses utilize one or more dams and/or wells to retain epoxy for securing a sensor. Some apparatuses utilize a pocket and one or more adjacent areas and various transitions for preventing epoxy from wicking to undesired areas of the apparatus. Some apparatuses include heat-sealable thermoplastic elastomers for welding a cap to the apparatus. Related methods of fabricating such apparatuses and/or housings are also provided.

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: Aspects of the present disclosure include systems and methods for generating and managing user authentication rules of a computing device. In an example, a computing device may include a memory storing instructions and a processor communicatively coupled with the memory and configured to execute the instructions. The processor may determine a state of the computing device, wherein the state of the computing device is one of a locked state or an unlocked state. The processor may determine a user authentication rule corresponding to the state of the computing device. The processor may also identify whether a combination of signals associated with the user authentication rule of the computing device are received by the computing device. The processor may also change or maintain the state of the computing device based on the combination of signals being received.

Abstract: The present invention relates to novel alpha5 subunit-selective negative allosteric modulators of GABAA receptors that have been deuterated to improve their medicinal properties by prolonging their half-lives, rendering them useful as fast-acting pharmaceutical treatments for depression related disorders.

Abstract: Various analyte sensing apparatuses and associated housings are provided. Some apparatuses comprise one or more caps. Some apparatuses comprise a two-part adhesive patch. Some apparatuses comprise one or more sensor bends configured to locate and/or hold a sensor in place during mounting. Some apparatuses utilize one or more dams and/or wells to retain epoxy for securing a sensor. Some apparatuses utilize a pocket and one or more adjacent areas and various transitions for preventing epoxy from wicking to undesired areas of the apparatus. Some apparatuses include heat-sealable thermoplastic elastomers for welding a cap to the apparatus. Related methods of fabricating such apparatuses and/or housings are also provided.

Abstract: A network device configured to communicate with a network executes a security protocol. The security protocol establishes a secure session with a security peer network device, exchanges security protected traffic with the security peer network device over a secure link, detects whether there is a security failure in the secure session, and upon detecting a security failure, signals there is a security failure. The network device also executes a routing protocol. The routing protocol maintains a routing table that includes a route to the security peer over the secure link, routes the security protected traffic along the route, and, upon receiving from the security protocol the signal that there is a security failure, removes the route from the routing table to stop the routing.

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: A crossbow including a frame with a riser and a center rail. First and second flexible limbs are attached to the riser. A draw string is received in string guide journals in first and second cams rotatably attached to the frame. The draw string unwinds from the string guide journals as it translates between a released configuration and a drawn configuration. The first and second cams include at least first and second power cable take-up journals, respectively. At least first and second power cables are attached to the first and second limbs and received in the first and second power cable take-up journals, respectively. As the crossbow is drawn from the released configuration to the drawn configuration the first and second power cables wrap onto the respective first and second power cable take-up journals.

Abstract: A user provides an identification (ID) signal (e.g. a biometric ID signal like a self-snapshot) to a trusted cloud-based provider. When the user attempts to authenticate with the cloud-based provider, a similar ID signal (e.g. another self-snapshot) for the user is captured and provided to the cloud-based provider. The cloud-based provider then obtains a secondary ID signal, or a combination of secondary ID signals, and utilizes the secondary ID signal, or signals, to identify a subset of user records to be searched for the ID signal. The subset of the records, rather than all of the user records, can then be searched for the ID signal. The cloud-based provider can then authenticate the user based on the results of the search of the subset of the user records.

Abstract: A crossbow includes a frame, a riser coupled to the frame, a first flexible limb, a second flexible limb, a third flexible limb, and a fourth flexible limb. A first cam assembly couples to the first flexible limb and the second limb and includes a first draw string journal, a first power cable journal, and a second power cable journal. A second cam assembly couples to the third flexible limb and the fourth flexible limb and includes a second draw string journal, a third power cable journal, and a fourth power cable journal. A draw string is received in the first draw string journal and the second draw string journal. Power cables cross over the center rail, above and below the draw string, and are received in the first power cable journal, the second power cable journal, the third power cable journal, and the fourth power cable journal, respectively.

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: A light-combining optical imager includes a spatially-curved waveguide-body complemented with at least two and preferably at least three holographic layers disposed on the surface(s) of the waveguide-body to couple light into the waveguide-body, optionally redirect its propagation inside the waveguide-body, and outcouple light from the waveguide body to form an optical image with reduced aberrations and—when desired—while expanding the pupil size of the imager upon propagation of light through the waveguide-body to achieve a one-to-one optical conjugation between an object and an image. At least one of the holographic layers includes potions having different diffraction efficiencies. At least one of the holographic layers is optionally configured to operate as a non-zero optical power lens element. Spatial separations between the holographic layers judiciously relate to dimensions of the portions of the holographic layers to achieve the desired result.