Abstract: Disclosed is a new class of lipid vesicles, liposoils, which have high oil content, low water content, and protein. The liposoils are made using a combination of a surfactant and either dried egg yolk or dried whole egg as the wall material, oil, and an aqueous diluent. Unlike most lipid vesicles, the liposoils can be made with an aqueous diluent having high salinity; in fact, sea water is a preferred aqueous diluent. Liposoils have particular applicability as a food for marine environments, such as a food source for filter feeders such as oysters. Methods of making the liposoils is also disclosed.

Abstract: The present invention relates to micellar nanoparticles and methods of their production. Micellar nanoparticles are made by hydrating a mixture of an oil, a stabilizer/surfactant, and an alcoholic initiator with an aqueous solution. These micellar nanoparticles are normally less than 100 nanometers in diameter. The micellar nanoparticles are particularly advantageous in delivering materials such as estradiol topically through the skin because their small size allows easy penetration.

Abstract: Monoclonal antibodies against the A chain of ricin have been found to be ective in protecting mammals from morbidity arising from exposure to ricin toxin. The neutralizing action of the antibodies does not appear to be mediated by complement or by immunoprecipitation. The antibodies of the invention are characterized as of isotype IgG1 having the binding characteristics which include: a) binding specifically to the neutralizing epitope of the ricin A chain and b) providing in vitro protection of at least 95% of EL-4 cells from 100 .eta.g/mL ricin challenge when said antibody is present in the tissue culture at a level of at least 1000 .eta.g/mL.

Abstract: An antibacterial oil-in-water emulsion for inhibiting the growth of Helicobacter pylori is disclosed. The oil-in-water emulsion of the invention comprises droplets of an oily discontinuous phase dispersed in a continuous phase. The oily discontinuous phase contains an oil carrier and a glycerol ester selected from the group consisting of glycerol monooleate and glycerol monostearate. The emulsion can be positively charged, negatively charged or chargeless. In one embodiment, the emulsion is positively charged and further comprises a cationic halogen-containing compound having a C.sub.12 -C.sub.16 chain as a positive charge producing agent. In another embodiment, the emulsion is negatively charged and further comprises an negative charge producing agent having a C.sub.12 -C.sub.22 chain. The disclosed emulsions can be administered to individuals, for example, orally, to treat or prevent Helicobacter pylori infections.

Abstract: A dry particle analyzer includes a vibrating sieve cup drizzling particles downwardly with first, second, and third sheath air flows being provided to separate the particles from boundary walls and to form the drizzling particles into a columnated flow for optical analysis. The particles drop vertically as a drizzle with gravitational assistance from a bulk sample to an analysis chamber. Along the way to the analysis chamber, the particles are subjected to an interval of high air flow shear, and to high turbulence of the air flow to break up agglomerations of particles.

Abstract: An antimicrobial lipid-containing oil-in-water emulsion comprising an agent selected from the group consisting of glycerol monooleate, glycerol trioleate, glycerol monolaurate, and glycerol dilaurate as the primary lipid and a cationic halogen-containing compound having a C.sub.12 -C.sub.16 chain as a positive charge producing agent is disclosed. The antimicrobial emulsion can be used in the form of a pharmaceutical preparation to inhibit the growth of a wide variety of infectious pathogens.

Abstract: An antimicrobial lipid-containing oil-in-water emulsion comprising an agent selected from the group consisting of glycerol monooleate, glycerol trioleate, glycerol monolaurate, and glycerol dilaurate as the primary lipid and a cationic halogen-containing compound having a C.sub.12 -C.sub.16 chain as a positive charge producing agent is disclosed. The antimicrobial emulsion can be used in the form of a pharmaceutical preparation to inhibit the growth of a wide variety of infectious pathogens.

Abstract: A dry particle analyzer includes a vibrating sieve cup drizzling particles downwardly with first and second sheath air flows provided to separate the particles from boundary walls and to form the drizzling particles into a curtain for optical analysis. The particles drop vertically as a drizzle with gravitational assistance from a bulk sample to the analysis passage, after which their direction of movement is changed to horizontal and then upward for removal from the analyzer.

Abstract: A particle analyzer includes a vibratory driver for particulate samples which are received in a sample cup to be drizzled under controller vibration to an analysis cell of the analyzer along with a conveying air stream. The driver is arranged to impose orbital oscillatory motion in a vertical plane on the sample cup to roll the sample while assisting in sifting of the sample through conventional sieve screen sample cups. Avoidance of vibratory classification of the sample by particle size while the test is in progress, as well as avoidance of sample compaction is achieved with the described driver. Additionally, an improved predictability of sample feed rate control results from the use of the orbital driver also with a novel sample cup not utilizing a sieve screen, but employing the inherent characteristic of particulate materials to form an repose angle when piled up.

Abstract: In order to avoid misfeeds from tray-loaded film, a lateral slit is provided through a backing sheet of composite media in a middle portion of a leader region where the film is adhered on both sides of the lateral slit to the backing sheet, thereby allowing the backing sheet to expand or contract at a different rate than the adjacent film.

Abstract: A method of producing large scale growth of parasites of the genus Toxoplasma is disclosed which comprises inoculating the microorganisms into a non-adherent human cell line, such as a monocytoid lymphoma cell line, and maintaining the cell line in tissue culture media capable of supporting the growth of the microorgranism while the cell line is being maintained. This large scale production allows for the development of vaccines for Toxoplasma microorganisms which previously have been hard to grow in the numbers needed to readily prepare vaccines, and allows for more rapid antibody detection procedures with regard to these microorganisms. There are also disclosed methods for preparing such vaccines, and methods for carrying out antibody detection assays.