Abstract: The present invention relates to a wireless item locator doorbell system comprising a doorbell unit and a moveable item locator unit in communication with said doorbell unit wherein said doorbell unit further comprises a motion sensor configured to actuate a message device, wherein said message device is configured to provide a message upon activation of said motion sensor, an actuating mechanism in communication with said motion sensor and/or message device, a transmitter configured to deliver a wireless signal upon actuation of said actuating mechanism, wherein said moveable item locator unit further comprises a receiver configured to receive signals from said transmitter of said doorbell unit, and a second message device configured to provide a message upon activation by said receiver.

Abstract: A compound of Formula I, a pharmaceutically acceptable salt, or solvate thereof: complexes with metals such as rhenium, technetium, and others to provide a complex for imaging tissues or treating disease, particularly where the metal is radioactive. Such complexes are specific to PSMA protein and can therefore be used in imaging or treating cancer of the prostate and other tissue where the protein is expressed.

Abstract: A compound that recognizes and binds to the CA-IX protein has Formula I, II, III, or IV. The compounds may include a radioactive element for radioimaging or therapeutic applications. Thus, pharmaceutical compositions may be prepared with one or more of the compounds of Formula I, II, III, or IV.

Abstract: Indoles that have activity as inhibitors of FAAH are described as are indoles and indole derivatives that have activity as inhibitors of DAO.

Abstract: According to one embodiment, an Ethernet switch includes a plurality of ports operable to receive and transmit Ethernet traffic. The Ethernet switch also includes system monitoring software operable to receive an indication from a user of a plurality of fault conditions for which generation of an alarm is desired. The system monitoring software is also operable to monitor the Ethernet switch for the plurality of fault conditions and generate a signal indicating a particular one of the plurality of fault conditions has occurred. The Ethernet switch further includes at least one relay responsive to the generated signal that is operable to turn on a respective alarm indicating a particular fault condition has occurred.

Abstract: A manufacturing process for the preparation of radiolabeled compounds of formula (I) includes reacting compounds of formula (II) with a source of readionuclide of a halogen in the presence of an oxidant under acidic condition, wherein: *I is 123I, 124I, 125I or 131I; R is lower alkyl, optionally substituted with one or more fluorine atoms; Q is C(O), O, NR?, S, S(O)2, C(O)2, (CH2)p; Y is C(O), O, NR?, S, S(O)2, C(O)2, (CH2)p; R? is H, C(O), S(O)2, C(O)2; Z is H, C1-C4 alkyl, benzyl, substituted benzyl or trialkylsilyl; m is 0, 1, 2, 3, 4 or 5; n is 0, 1, 2, 3, 4, 5 or 6; and p is 0, 1, 2, 3, 4, 5 or 6.

Abstract: A fault-tolerant stack of low cost switches each having only two dual-purpose uplinks is enabled by utilizing a specified topology for connecting the uplinks and implementing a recovery algorithm on each switch.

Abstract: Complexes of heterocyclic radionuclides are prepared based upon ligands having substituted pyridyl and imidazolyl groups. The ligands are bifunctional, having amino acid residues that may act as a linker to a bioactive molecule, and a tridentate chelator that may complex the radionuclide. The bioactive molecule may be a peptide or somatostatin.

Abstract: A compound of Formula I, a pharmaceutically acceptable salt, or solvate thereof: complexes with metals such as rhenium, technetium, and others to provide a complex for imaging tissues or treating disease, particularly where the metal is radioactive. Such complexes are specific to PSMA protein and can therefore be used in imaging or treating cancer of the prostate and other tissue where the protein is expressed.

Abstract: A compound that recognizes and binds to the CA-IX protein has Formula I, II, III, or IV. The compounds may include a radioactive element for radioimaging or therapeutic applications. Thus, pharmaceutical compositions may be prepared with one or more of the compounds of Formula I, II, III, or IV.

Abstract: Novel radiopharmaceuticals that are useful in diagnostic imaging and therapeutic treatment of disease characterized by overexpression of seprase include complexes that contains a proline moiety and a radionuclide adapted for radioimaging and/or radiotherapy:

Abstract: The present invention relates to a wireless item locator doorbell system comprising a doorbell unit and a moveable item locator unit in communication with said doorbell unit wherein said doorbell unit further comprises a motion sensor configured to actuate a message device, wherein said message device is configured to provide a message upon activation of said motion sensor, an actuating mechanism in communication with said motion sensor and/or message device, a transmitter configured to deliver a wireless signal upon actuation of said actuating mechanism, wherein said moveable item locator unit further comprises a receiver configured to receive signals from said transmitter of said doorbell unit, and a second message device configured to provide a message upon activation by said receiver.

Abstract: Indoles that have activity as inhibitors of FAAH are described as are indoles and indole derivatives that have activity as inhibitors of DAO.

Abstract: Novel radiopharmaceuticals that are useful in diagnostic imaging and therapeutic treatment of disease characterized by over expression of CA-IX comprise a complex that contains a sulfonamide moiety which is capable of binding the active catalytic site of CA-IX, and a radionuclide adapted for radioimaging and/or radiotherapy:

Abstract: Methods of imaging tissue of a mammal which expresses chymase include administering to the mammal an effective amount of a radiolabeled chymase inhibitor.

Abstract: According to one embodiment, an Ethernet switch includes a plurality of ports operable to receive and transmit Ethernet traffic. The Ethernet switch also includes system monitoring software operable to receive an indication from a user of a plurality of fault conditions for which generation of an alarm is desired. The system monitoring software is also operable to monitor the Ethernet switch for the plurality of fault conditions and generate a signal indicating a particular one of the plurality of fault conditions has occurred. The Ethernet switch further includes at least one relay responsive to the generated signal that is operable to turn on a respective alarm indicating a particular fault condition has occurred.

Abstract: According to one embodiment, an Ethernet switch includes a plurality of ports operable to receive and transmit Ethernet traffic. The Ethernet switch also includes system monitoring software operable to receive an indication from a user of a plurality of fault conditions for which generation of an alarm is desired. The system monitoring software is also operable to monitor the Ethernet switch for the plurality of fault conditions and generate a signal indicating a particular one of the plurality of fault conditions has occurred. The Ethernet switch further includes at least one relay responsive to the generated signal that is operable to turn on a respective alarm indicating a particular fault condition has occurred.

Abstract: Conjugates, methods and kits are described for imaging tissues and organs that express one or more peptidases. In a preferred embodiment of the invention, a series of di-(2-pyridylmethyl)amine (D) ligands, which can bind M(CO)3+ [M=Tc or Re], were coupled to lisinopril (L). Aliphatic tethers with varying number of methylene groups (3, 4, 5, and 7; D(C4)L, D(C5)L, D(C6)L, and D(C8)L, respectively) were utilized, with in vitro inhibitory activity increasing with increasing number of methylene groups. The D(C8)L conjugate was observed to be significantly more potent than D(C4)L. In vivo specificity for ACE was studied in both tissue distribution and gamma imaging studies, demonstrating localization in tissues with high ACE content. Localization was blocked by pretreatment with lisinopril.

Abstract: The invention features compounds that are inhibitors of COX-2 activity. Certain of the compounds are inhibitors of FAAH activity as well as COX-2 activity. The compounds include a 5-membered or 6-membered substituted or unsubstituted heteroaryl or heterocyclyl ring having one or two heteroatoms selected from the group consisting of O, S, and N that is linked to two substituted or unsubstituted 6-membered aryl or heteroaryl groups that can be the same or different.