Patents by Inventor Cris M. Olsen

Cris M. Olsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nicotinic acetylcholine receptor modulators
    Patent number: 8697722
    Abstract: The disclosure provides compounds capable of selectively or non-selectively modulating nicotinic acetylcholine receptors. The compounds, compositions, and methods described herein are useful, for example, in treating patients suffering from various medical conditions including pain, chemical addictions, Parkinson's disease, Alzheimer's disease, and neurodegenerative disorders. In one embodiment, the compounds comprise a 7- to 11-membered azabicyclo ring.
    Type: Grant
    Filed: November 2, 2007
    Date of Patent: April 15, 2014
    Assignee: SRI International
    Inventors: Faming Jiang, Taline Khroyan, Cris M. Olsen, Willma E. Polgar, Lawrence R. Toll, Nurulain T. Zaveri
  • Nicotinic Acetylcholine Receptor Modulators
    Publication number: 20090118326
    Abstract: The disclosure provides compounds capable of selectively or non-selectively modulating nicotinic acetylcholine receptors. The compounds, compositions, and methods described herein are useful, for example, in treating patients suffering from various medical conditions including pain, chemical addictions, Parkinson's disease, Alzheimer's disease, and neurodegenerative disorders. In one embodiment, the compounds comprise a 7- to 11-membered azabicyclo ring.
    Type: Application
    Filed: November 2, 2007
    Publication date: May 7, 2009
    Inventors: Faming Jiang, Taline Khroyan, Cris M. Olsen, Willma E. Polgar, Lawrence R. Toll, Nurulain T. Zaveri
  • Di-aryl ethers and their derivatives as anti-cancer agents
    Patent number: 6169104
    Abstract: The present invention relates, inter alia, to compounds that bind tubulin and exhibit anti-mitotic properties and to methods of using such compounds to inhibit abnormal cell mitosis and, in particular, to inhibit tumor cell growth. In addition, methods are presented of treating mammalian diseases associated with undesired and uncontrolled angiogenesis.
    Type: Grant
    Filed: March 25, 1998
    Date of Patent: January 2, 2001
    Assignees: Large Scale Biology Corporation, SRI International
    Inventors: Daniel Tus{acute over (e)}, Xiaoying Chen, Charles K. Hiebert, Cris M. Olsen, Keith Laderoute, Nahid Waleh, A. Merrill Knapp
  • Orally active LHRH analogs
    Patent number: 4705778
    Abstract: Incorporation of a ketomethylene or a hydroxyethylene group in place of the amide linking group between the Pro.sup.9 and Gly.sup.10 residues of LHRH and its analogs improves the oral activity of LHRH or its analogs.
    Type: Grant
    Filed: October 22, 1985
    Date of Patent: November 10, 1987
    Assignee: SRI International
    Inventors: Ronald G. Almquist, Cris M. Olsen