Patents by Inventor Cristhina Kellen FAE

Cristhina Kellen FAE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FIMH MUTANTS, COMPOSITIONS THEREWITH AND USE THEREOF
    Publication number: 20230406890
    Abstract: Polypeptides comprising a FimH lectin domain comprising at least one an amino acid mutation that causes the FimH lectin domain to be in the low affinity conformation for mannose are described. Pharmaceutical compositions which comprise such polypeptides and methods of stimulating an immune response in a subject in need thereof by administration of the polypeptide are further described.
    Type: Application
    Filed: June 26, 2023
    Publication date: December 21, 2023
    Inventors: Jan GRIJPSTRA, Marleen Eveline WEERDENBURG, Jeroen GEURTSEN, Cristhina Kellen FAE, Jakob Louris FEITSMA
  • FimH mutants, compositions therewith and use thereof
    Patent number: 11725028
    Abstract: Polypeptides comprising a FimH lectin domain comprising at least one an amino acid mutation that causes the FimH lectin domain to be in the low affinity conformation for mannose are described. Pharmaceutical compositions which comprise such polypeptides and methods of stimulating an immune response in a subject in need thereof by administration of the polypeptide are further described.
    Type: Grant
    Filed: January 11, 2022
    Date of Patent: August 15, 2023
    Assignee: JANSSEN PHARMACEUTICALS, INC.
    Inventors: Jan Grijpstra, Marleen Eveline Weerdenburg, Jeroen Geurtsen, Cristhina Kellen Fae, Jakob Louris Feitsma
  • FimH mutant, compositions therewith and use thereof
    Patent number: 11421003
    Abstract: Polypeptides comprising a FimH lectin domain comprising an amino acid mutation that causes the FimH lectin domain to be in the low affinity conformation for mannose are described. Pharmaceutical compositions which comprise such polypeptides and methods of stimulating an immune response in a subject in need thereof by administration of the polypeptide are further described.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: August 23, 2022
    Assignee: Janssen Pharmaceuticals, Inc.
    Inventors: Jan Grijpstra, Marleen Eveline Weerdenburg, Jeroen Geurtsen, Cristhina Kellen Fae, Jakob Louris Feitsma
  • FIMH MUTANTS, COMPOSITIONS THEREWITH AND USE THEREOF
    Publication number: 20220220159
    Abstract: Polypeptides comprising a FimH lectin domain comprising at least one an amino acid mutation that causes the FimH lectin domain to be in the low affinity conformation for mannose are described. Pharmaceutical compositions which comprise such polypeptides and methods of stimulating an immune response in a subject in need thereof by administration of the polypeptide are further described.
    Type: Application
    Filed: January 11, 2022
    Publication date: July 14, 2022
    Inventors: Jan GRIJPSTRA, Marleen Eveline WEERDENBBURG, Jeroen GEURTSEN, Cristhina Kellen FAE, Jakob Louris FEITSMA
  • FimH mutant, compositions therewith and use thereof
    Publication number: 20210221856
    Abstract: Polypeptides comprising a FimH lectin domain comprising an amino acid mutation that causes the FimH lectin domain to be in the low affinity conformation for mannose are described. Pharmaceutical compositions which comprise such polypeptides and methods of stimulating an immune response in a subject in need thereof by administration of the polypeptide are further described.
    Type: Application
    Filed: January 15, 2021
    Publication date: July 22, 2021
    Inventors: Jan GRIJPSTRA, Marleen Eveline WEERDENBURG, Jeroen GEURTSEN, Cristhina Kellen FAE, Jakob Louris FEITSMA