Patents by Inventor Cristian DROPPELMANN

Cristian DROPPELMANN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATMENT OF NEURON DEGENERATION
    Publication number: 20240350581
    Abstract: A method for reducing, inhibiting, preventing or treating cytotoxicity in a cell, the method comprising expressing or overexpressing in the cell a Rho guanine nucleotide exchange factor (RGNEF), or a RGNEF analog or agonist, or a leucine rich domain of RGNEF, whereby the cytotoxicity in the cell is reduced, inhibited, prevented or treated. Also a method of shifting the survival curve of a subject and thereby increasing life expectancy of the subject by administering to the subject a physiologically effective amount of a peptide comprising A Rho Guanine Nucleotide Exchange Factor (RGNEF) protein, or a RGNEF analog or agonist, or a leucine rich domain of RGNEF, or expressing or overexpressing RGNEF or a RGNEF analog or agonist or a leucine rich domain of RGNEF in the subject.
    Type: Application
    Filed: April 29, 2022
    Publication date: October 24, 2024
    Applicant: THE UNIVERSITY OF WESTERN ONTARIO
    Inventors: Michael STRONG, Cristian DROPPELMANN, Kathryn VOLKENING, Danae CAMPOS-MELO, Hind AMZIL