Patents by Inventor Cristian L. Harrison

Cristian L. Harrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solid forms of N-[2,4-Bis(1,1-dimethyethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquioline-3-carboxamide
    Patent number: 8623894
    Abstract: Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide are described herein, including crystalline forms thereof.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: January 7, 2014
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: John DeMattei, Yushi Feng, Cristian L. Harrison, Adam R. Looker, Praveen Mudunuri, Stefanie Roeper, Yuegang Zhang
  • Preparation of protected alpha-keto beta-amino esters and amides
    Patent number: 8378124
    Abstract: The invention provides ?-sulfonamide ?-keto esters and amides in which the ?-keto is protected as a 1,3-dithiolane derivative. Also provided are methods for preparing such esters and amides and for incorporating them into peptides.
    Type: Grant
    Filed: December 30, 2010
    Date of Patent: February 19, 2013
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: William A. Nugent, Adam R. Looker, Raymond E. Forslund, Theodore A. Martinot, Cristian L. Harrison, Shereen Ibrahim
  • Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
    Patent number: 8362253
    Abstract: Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide are described herein, including crystalline forms thereof.
    Type: Grant
    Filed: March 6, 2012
    Date of Patent: January 29, 2013
    Assignee: Vertex Pharmaceutical Incorporated
    Inventors: John DeMattei, Yushi Feng, Cristian L. Harrison, Adam R. Looker, Praveen Mudunuri, Stefanie Roeper, Yuegang Zhang
  • Preparation of Protected Alpha-Keto Beta-Amino Esters and Amides
    Publication number: 20110213161
    Abstract: The invention provides ?-sulfonamide ?-keto esters and amides in which the ?-keto is protected as a 1,3-dithiolane derivative. Also provided are methods for preparing such esters and amides and for incorporating them into peptides.
    Type: Application
    Filed: December 30, 2010
    Publication date: September 1, 2011
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: William A. Nugent, Adam R. Looker, Raymond E. Forslund, Theodore A. Martinot, Cristian L. Harrison, Shereen Ibrahim