Patents by Inventor Cristiana Guiducci

Cristiana Guiducci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN TOLL-LIKE RECEPTOR INHIBITORS AND METHODS OF USE THEREOF
    Publication number: 20150252363
    Abstract: Provided herein are human Toll-like receptor (TLR)-inhibitors and methods for use in individuals having an autoimmune disease or an inflammatory disorder. The TLR inhibitors of the present disclosure are polynucleotides comprising an inhibitory motif for one or more of TLR7, TLR8 and TLR9.
    Type: Application
    Filed: September 27, 2013
    Publication date: September 10, 2015
    Inventors: Cristiana Guiducci, Karen L. Fearon, Franck Barrat
  • METHODS OF TREATMENT USING TLR7 AND/OR TLR9 INHIBITORS
    Publication number: 20150203850
    Abstract: The application relates to compositions and methods of regulating an immune response comprising inhibitors of TLR7 and/or TLR9, such as immunoregulatory polynucleotides and/or immunoregulatory compounds. The application also relates to compositions and methods for predicting and/or determining responsiveness of a disease to treatment comprising inhibitors of TLR7 and/or TLR9.
    Type: Application
    Filed: November 25, 2014
    Publication date: July 23, 2015
    Inventors: Franck BARRAT, Robert L. COFFMAN, Cristiana GUIDUCCI
  • Transgenic mice expressing human toll-like receptor 8
    Patent number: 9063123
    Abstract: Provided herein are human Toll-like receptor 8 (TLR8)-expressing transgenic s and methods of use thereof.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: June 23, 2015
    Assignee: Dynavax Technologies Corporation
    Inventors: Franck Barrat, Robert L. Coffman, Cristiana Guiducci
  • Methods and compositions for inhibition of immune responses and autoimmunity
    Patent number: 8962579
    Abstract: The application relates to the use of immunoregulatory polynucleotides and/or immunoregulatory compounds in combination with other therapeutic agents. The application further relates to immunoregulatory polynucleotides and/or immunoregulatory compounds comprising a modified immunoregulatory sequence. It also relates to the administration of the immunoregulatory polynucleotides and/or immunoregulatory compounds comprising a modified immunoregulatory sequence to regulate an immune response.
    Type: Grant
    Filed: April 26, 2010
    Date of Patent: February 24, 2015
    Assignee: Dynavax Technologies Corporation
    Inventors: Franck Barrat, Robert L. Coffman, Tracy Matray, Cristiana Guiducci
  • Methods of treatment using TLR7 and/or TLR9 inhibitors
    Patent number: 8940310
    Abstract: The application relates to compositions and methods of regulating an immune response comprising inhibitors of TLR7 and/or TLR9, such as immunoregulatory polynucleotides and/or immunoregulatory compounds. The application also relates to compositions and methods for predicting and/or determining responsiveness of a disease to treatment comprising inhibitors of TLR7 and/or TLR9.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: January 27, 2015
    Assignee: Dynavax Technologies Corporation
    Inventors: Franck Barrat, Robert L. Coffman, Cristiana Guiducci
  • HUMAN TOLL-LIKE RECEPTOR INHIBITORS AND METHODS OF USE THEREOF
    Publication number: 20140094504
    Abstract: Provided herein are human Toll-like receptor (TLR)-inhibitors and methods for use in individuals having an autoimmune disease or an inflammatory disorder. The TLR inhibitors of the present disclosure are polynucleotides comprising an inhibitory motif for one or more of TLR7, TLR8 and TLR9.
    Type: Application
    Filed: March 15, 2013
    Publication date: April 3, 2014
    Applicant: Dynavax Technologies Corporation
    Inventors: Cristiana GUIDUCCI, Karen L. FEARON, Franck BARRAT
  • METHODS OF TREATMENT USING TLR7 AND/OR TLR9 INHIBITORS
    Publication number: 20130156814
    Abstract: The application relates to compositions and methods of regulating an immune response comprising inhibitors of TLR7 and/or TLR9, such as immunoregulatory polynucleotides and/or immunoregulatory compounds. The application also relates to compositions and methods for predicting and/or determining responsiveness of a disease to treatment comprising inhibitors of TLR7 and/or TLR9.
    Type: Application
    Filed: June 16, 2011
    Publication date: June 20, 2013
    Applicant: Dynavax Technologies Corporation
    Inventors: Franck Barrat, Robert L. Coffman, Cristiana Guiducci
  • TLR8 TRANSGENIC ANIMALS
    Publication number: 20120252051
    Abstract: Provided herein are human Toll-like receptor 8 (TLR8)-expressing transgenic animals and methods of use thereof.
    Type: Application
    Filed: March 29, 2012
    Publication date: October 4, 2012
    Applicant: DYNAVAX TECHNOLOGIES CORPORATION
    Inventors: Franck Barrat, Robert L. Coffman, Cristiana Guiducci
  • METHODS AND COMPOSITIONS FOR INHIBITION OF IMMUNE RESPONSES AND AUTOIMMUNITY
    Publication number: 20110003885
    Abstract: The application relates to the use of immunoregulatory polynucleotides and/or immunoregulatory compounds in combination with other therapeutic agents. The application further relates to immunoregulatory polynucleotides and/or immunoregulatory compounds comprising a modified immunoregulatory sequence. It also relates to the administration of the immunoregulatory polynucleotides and/or immunoregulatory compounds comprising a modified immunoregulatory sequence to regulate an immune response.
    Type: Application
    Filed: April 26, 2010
    Publication date: January 6, 2011
    Applicant: DYNAVAX TECHNOLOGIES CORPORATION
    Inventors: FRANCK BARRAT, ROBERT L. COFFMAN, TRACY MATRAY, CRISTIANA GUIDUCCI
  • Inhibition of type I in IFN production
    Publication number: 20090131512
    Abstract: The invention provides methods for decreasing type I IFN production by human plasmacytoid dendritic cells in response to TLR activation.
    Type: Application
    Filed: October 30, 2008
    Publication date: May 21, 2009
    Inventors: Franck Barrat, Cristiana Guiducci, Vassili Soumelis