Abstract: An integrated condenser is described. This integrated condenser includes an outer surface region on a sampler surface that facilitates condensing at least a component in a received gas-phase sample into liquid-phase droplets on the sampler surface, and aggregating and moving the condensed droplets radially toward an inner surface region on the sampler surface that receives the condensed droplets. For example, the outer surface region may include a set of micro-patterned concentric rings, each of which includes a set of radially oriented wall-groove pairs. Moreover, the sampler surface may be increasingly less hydrophobic along a radial direction toward the center of the sampler surface, thereby creating an axisymmetric wettability gradient.

Abstract: A method for analyzing droplets is described. The droplets can be received on an outer surface region of a sampler surface disposed on a substrate, wherein the sampler surface is increasingly less hydrophobic along a radial direction toward the center of the sampler surface. Next, the droplets can be aggregated and moved toward the center of the sampler surface. The droplets can then be received at an inner surface region of the sampler surface. Next, the droplets can be analyzed using an analysis mechanism in an area in the inner surface region.

Abstract: A method for analyzing droplets is described. The droplets can be received on an outer surface region of a sampler surface disposed on a substrate, wherein the sampler surface is increasingly less hydrophobic along a radial direction toward the center of the sampler surface. Next, the droplets can be aggregated and moved toward the center of the sampler surface. The droplets can then be received at an inner surface region of the sampler surface. Next, the droplets can be analyzed using an analysis mechanism in an area in the inner surface region.

Abstract: A micro-analyzer is described. This micro-analyzer includes an outer surface region on a sampler surface that receives liquid droplets, and aggregates and moves the droplets radially toward an inner surface region on the sampler surface that receives the droplets. For example, the outer surface region may include a set of micro-patterned concentric rings, each of which includes a set of radially oriented wall-groove pairs. Moreover, the sampler surface may be increasingly less hydrophobic along a radial direction toward the center of the sampler surface, thereby creating an axisymmetric wettability gradient. After the droplets are aggregated, an analysis mechanism in an area within the inner surface region performs analysis on the aggregated droplets.

Abstract: A micro-analyzer is described. This micro-analyzer includes an outer surface region on a sampler surface that receives liquid droplets, and aggregates and moves the droplets radially toward an inner surface region on the sampler surface that receives the droplets. For example, the outer surface region may include a set of micro-patterned concentric rings, each of which includes a set of radially oriented wall-groove pairs. Moreover, the sampler surface may be increasingly less hydrophobic along a radial direction toward the center of the sampler surface, thereby creating an axisymmetric wettability gradient. After the droplets are aggregated, an analysis mechanism in an area within the inner surface region performs analysis on the aggregated droplets.

Abstract: An integrated condenser is described. This integrated condenser includes an outer surface region on a sampler surface that facilitates condensing at least a component in a received gas-phase sample into liquid-phase droplets on the sampler surface, and aggregating and moving the condensed droplets radially toward an inner surface region on the sampler surface that receives the condensed droplets. For example, the outer surface region may include a set of micro-patterned concentric rings, each of which includes a set of radially oriented wall-groove pairs. Moreover, the sampler surface may be increasingly less hydrophobic along a radial direction toward the center of the sampler surface, thereby creating an axisymmetric wettability gradient.

Abstract: One embodiment of the present invention provides a photosensitive organo-metallic hybrid material which functions as both a structural material and a photoresist material. More specifically, this photosensitive organo-metallic hybrid material includes an organo-metallic compound comprised of at least one unsaturated double bond. The photosensitive organo-metallic hybrid material also includes a cross-linking agent comprised of at least two unsaturated double bonds capable of cross-linking the organo-metallic compound to form an organo-metallic hybrid material. Additionally, the photosensitive organo-metallic hybrid material includes a photoactive compound capable of absorbing exposure light during a photolithography process to form the photosensitive organo-metallic hybrid material.

Abstract: Disclosed herein are systems, methods and apparatus, for detection and identification of analytes in a volatilized or volatilizable sample, using the mobility-based signature that is produced when the volatilized sample is passed through an ion mobility based analyzer.

Abstract: The invention provides an interface assembly for delivering an ionized analyte from an ionization apparatus into an ion mobility spectrometer. This allows analysis of biological and non-biological samples, even non-volatile solids, via differential mobility spectrometry, without fragmentation of molecules. The invention also provides portable sample analysis systems that operate at ambient pressure. Systems of the invention may be used for high molecular weight species detection, for example, drinking water contaminants, pathogenic biological agents, bio-organic substances, non-biological material, peptides, proteins, oligonucleotides, polymers, bacteria, and hydrocarbons.

Abstract: Disclosed herein are systems, methods and apparatus, for detection and identification of analytes in a volatilized or volatilizable sample, using the mobility-based signature that is produced when the volatilized sample is passed through an ion mobility based analyzer.

Abstract: The invention provides methods for aligning and filtering chromatograms representative of complex mixture samples. In one embodiment, the invention includes identifying and matching related peaks to determine a temporal offset, and applying a nonlinear temporal shift to account for the offset. In other embodiments, the invention provides methods for smoothing chromatographic data by application of an autoregressive filter to provide improved signal-to-noise ratio, data compression, and resolution. The alignment and filtering methods may be performed separately or combined. In certain embodiments, the invention provides improved chromatographic pattern recognition capability and improved classification of samples of complex chemical and/or biological mixtures.

Abstract: An asymmetric field ion mobility spectrometer for breath analysis and a system for analysis of a sample of breath taken from a patient.

Abstract: Disclosed herein are systems, methods and apparatus, for detection and identification of analytes in a volatilized or volatilizable sample, using the mobility-based signature that is produced when the volatilized sample is passed through a differential ion mobility spectrometry (DMS) device.