Patents by Inventor Cristina Ferrone

Cristina Ferrone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR CHIMERIC ANTIGEN RECEPTOR TARGETING CANCER CELLS
    Publication number: 20210252067
    Abstract: The present invention provides a chimeric antigen receptor (CAR) that recognizes CSPG4 as well as methods of use in the treatment of diseases and disorders.
    Type: Application
    Filed: May 24, 2019
    Publication date: August 19, 2021
    Inventors: Gianpietro Dotti, Soldano Ferrone, Hannah Reid Hudson, Elena Dukhovlinova, Cristina Ferrone, Xinhui Wang
  • METHODS AND COMPOSITIONS FOR CHIMERIC ANTIGEN RECEPTOR TARGETING CANCER CELLS
    Publication number: 20200369743
    Abstract: The present invention provides a chimeric antigen receptor (CAR) that recognizes B7-H3 (CD276), as well as methods of use in the treatment of diseases and disorders.
    Type: Application
    Filed: December 30, 2019
    Publication date: November 26, 2020
    Inventors: Gianpietro Dotti, Soldano Ferrone, Hongwei Du, Xinhui Wang, Cristina Ferrone
  • Methods and compositions for chimeric antigen receptor targeting cancer cells
    Patent number: 10519214
    Abstract: The present invention provides a chimeric antigen receptor (CAR) that recognizes B7-H3 (CD276), as well as methods of use in the treatment of diseases and disorders.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: December 31, 2019
    Assignees: The University of North Carolina at Chapel Hill, The General Hospital Corporation
    Inventors: Gianpietro Dotti, Soldano Ferrone, Hongwei Du, Xinhui Wang, Cristina Ferrone
  • METHODS AND COMPOSITIONS FOR CHIMERIC ANTIGEN RECEPTOR TARGETING CANCER CELLS
    Publication number: 20190153063
    Abstract: The present invention provides a chimeric antigen receptor (CAR) that recognizes B7-H3 (CD276), as well as methods of use in the treatment of diseases and disorders.
    Type: Application
    Filed: January 30, 2019
    Publication date: May 23, 2019
    Inventors: Gianpietro Dotti, Soldano Ferrone, Hongwei Du, Xinhui Wang, Cristina Ferrone
  • Methods and compositions for chimeric antigen receptor targeting cancer cells
    Patent number: 10233226
    Abstract: The present invention provides a chimeric antigen receptor (CAR) that recognizes B7-H3 (CD276), as well as methods of use in the treatment of diseases and disorders.
    Type: Grant
    Filed: June 19, 2018
    Date of Patent: March 19, 2019
    Assignees: The University of North Carolina at Chapel Hill, The General Hospital Corporation
    Inventors: Gianpietro Dotti, Soldano Ferrone, Hongwei Du, Xinhui Wang, Cristina Ferrone
  • Combination treatments with sonic hedgehog inhibitors
    Patent number: 10220091
    Abstract: Methods for treating cancer using a combination of an inhibitor of the sonic hedgehog signaling pathway (e.g., LDE225) with radiation and a tumor antigen-specific monoclonal antibody (e.g., heat shock protein (HSP) glucose regulated protein of 94000 daltons (Grp94)-specific mAb W9, or chondroitin sulfate proteoglycan 4 (CSPG4)-targeted mAbs), or with a BRAF inhibitor, e.g., in BRAF inhibitor resistant cancers.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: March 5, 2019
    Assignee: The General Hospital Corporation
    Inventors: Francesco Sabbatino, Yangyang Wang, Xinhui Wang, Steven Isakoff, Cristina Ferrone, Joe Schwab, Soldano Ferrone
  • METHODS AND COMPOSITIONS FOR CHIMERIC ANTIGEN RECEPTOR TARGETING CANCER CELLS
    Publication number: 20180371053
    Abstract: The present invention provides a chimeric antigen receptor (CAR) that recognizes B7-H3 (CD276), as well as methods of use in the treatment of diseases and disorders.
    Type: Application
    Filed: June 19, 2018
    Publication date: December 27, 2018
    Inventors: Gianpietro Dotti, Soldano Ferrone, Hongwei Du, Xinhui Wang, Cristina Ferrone
  • Combination Treatments with Sonic Hedgehog Inhibitors
    Publication number: 20160045598
    Abstract: Methods for treating cancer using a combination of an inhibitor of the sonic hedgehog signaling pathway (e.g., LDE225) with radiation and a tumor antigen-specific monoclonal antibody (e.g., heat shock protein (HSP) glucose regulated protein of 94000 daltons (Grp94)-specific mAb W9, or chondroitin sulfate proteoglycan 4 (CSPG4)-targeted mAbs), or with a BRAF inhibitor, e.g., in BRAF inhibitor resistant cancers.
    Type: Application
    Filed: April 3, 2014
    Publication date: February 18, 2016
    Inventors: Francesco Sabbatino, Yangyang Wang, Xinhui Wang, Steven Isakoff, Cristina Ferrone, Joe Schwab, Soldano Ferrone