Patents by Inventor Cristina Maria Concetta ZAPPULLA

Cristina Maria Concetta ZAPPULLA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11672760
    Abstract: Provided are oil-in-water microemulsions for formulating pharmaceutically active compounds. The microemulsions contain oils, surfactants, water, and the pharmaceutical compounds, and are produced by mixing an aqueous phase and a lipid phase in which each phase contains at least one surfactant in a defined ratio whereby the resulting microemulsion has very small dispersed particles and is thermodynamically very stable.
    Type: Grant
    Filed: March 19, 2021
    Date of Patent: June 13, 2023
    Assignees: SIFI S.p.A., Consiglio Nazionale delle Ricerche
    Inventors: Elena Solfato, Ilenia Abbate, Cristina Maria Concetta Zappulla, Manuela Santonocito, Santa Viola, Sandro De Falco, Francesco Giuliano
  • Publication number: 20230047895
    Abstract: The present invention relates to a sterile buffered eye topical composition containing metabolites of the fermentation of Lactobacillus pertaining to the species casei or paracasei and for ophthalmic use of the composition in the prevention or treatment of microbial eye infections, eye allergies, vernal keratoconjunctivitis and keratoconjunctivitis sicca and blepharitis.
    Type: Application
    Filed: December 4, 2020
    Publication date: February 16, 2023
    Inventors: Elena SOLFATO, Andrea SUDANO ROCCARO, Cristina Maria Concetta ZAPPULLA, Carmela Giovanna SPOTO, Donato SPINA, Veronica PEPE, Manuela SANTONOCITO, Angelo PRICOCO, Santa VIOLA, Maria Cristina CURATOLO, Maria Grazia MAZZONE, Giuseppe DE PASQUALE, Francesco GIULIANO
  • Publication number: 20210205217
    Abstract: Provided are oil-in-water microemulsions for formulating pharmaceutically active compounds. The microemulsions contain oils, surfactants, water, and the pharmaceutical compounds, and are produced by mixing an aqueous phase and a lipid phase in which each phase contains at least one surfactant in a defined ratio whereby the resulting microemulsion has very small dispersed particles and is thermodynamically very stable.
    Type: Application
    Filed: March 19, 2021
    Publication date: July 8, 2021
    Inventors: Elena SOLFATO, Ilenia ABBATE, Cristina Maria Concetta ZAPPULLA, Manuela SANTONOCITO, Santa VIOLA, Sandro DE FALCO, Francesco GIULIANO
  • Patent number: 10980745
    Abstract: Provided are oil-in-water microemulsions for formulating pharmaceutically active compounds. The microemulsions contain oils, surfactants, water, and the pharmaceutical compounds, and are produced by mixing an aqueous phase and a lipid phase in which each phase contains at least one surfactant in a defined ratio whereby the resulting microemulsion has very small dispersed particles, and, is thermodynamically very stable.
    Type: Grant
    Filed: October 1, 2019
    Date of Patent: April 20, 2021
    Assignees: SIFI S.p.A., Consiglio Nazionale delle Ricerche
    Inventors: Elena Solfato, Ilenia Abbate, Cristina Maria Concetta Zappulla, Manuela Santonocito, Santa Viola, Sandro De Falco, Francesco Giuliano
  • Publication number: 20200390699
    Abstract: Provided are oil-in-water microemulsions for formulating pharmaceutically active compounds. The microemulsions contain oils, surfactants, water, and the pharmaceutical compounds, and are produced by mixing an aqueous phase and a lipid phase in which each phase contains at least one surfactant in a defined ratio whereby the resulting microemulsion has very small dispersed particles, and, is thermodynamically very stable.
    Type: Application
    Filed: October 1, 2019
    Publication date: December 17, 2020
    Inventors: Elena SOLFATO, llenia ABBATE, Cristina Maria Concetta ZAPPULLA, Manuela SANTONOCITO, Santa VIOLA, Sandro DE FALCO, Francesco GIULIANO