Patents by Inventor Cristina MUELLER

Cristina MUELLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • [161Tb]-BASED RADIOPEPTIDES
    Publication number: 20230293736
    Abstract: A radiopeptide is provided which comprises (a) a radionuclide, wherein the radionuclide is terbium-161, (b) a chelator coordinating terbium-161, and (c) a peptide or peptide analogue, which is a somatostatin receptor (SSTR) antagonist. The radiopeptide is suitable for use in the treatment of tumor diseases.
    Type: Application
    Filed: February 21, 2023
    Publication date: September 21, 2023
    Inventors: Cristina Müller, Roger Schibli, Nicolas Philip Van Der Meulen, Francesca Borgna, Damian Wild, Melpomeni Fani
  • [161Tb]-BASED RADIOPEPTIDES
    Publication number: 20230165981
    Abstract: A radiopeptide is provided which comprises (a) a radionuclide, wherein the radionuclide is terbium-161, (b) a chelator coordinating terbium-161, and (c) a peptide or peptide analogue, which is a somatostatin receptor (SSTR) antagonist. The radiopeptide is suitable for use in the treatment of tumor diseases.
    Type: Application
    Filed: September 29, 2022
    Publication date: June 1, 2023
    Inventors: Cristina Müller, Roger Schibli, Nicolas Philip Van Der Meulen, Francesca Borgna, Damian Wild, Melpomeni Fani
  • PSMA-binding agents and uses thereof
    Patent number: 11629201
    Abstract: The present invention provides novel compounds that are useful as radiopharmaceuticals, imaging agents and for treatment of cancer.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: April 18, 2023
    Assignees: ITM Isotope Technologies Munich SE, Paul Scherrer Institut
    Inventors: Martina Benesova, Cristina Müller, Christoph Umbricht, Roger Schibli, Konstantin Zhernosekov
  • NOVEL TUMOR ANTIGEN BINDING AGENTS AND USES THEREOF
    Publication number: 20220024882
    Abstract: The present invention provides compounds according to General Formula (1)(i) or (1)(ii): wherein A is a diagnostic or therapeutic agent comprising a binding site for a tumor antigen, and the spacer comprises at least one C—N bond.
    Type: Application
    Filed: November 28, 2019
    Publication date: January 27, 2022
    Inventors: Martina Benesova, Cristina Müller, Christoph Umbricht, Roger Schibli, Konstantin Zhernosekov, Luisa Maria Deberle
  • NOVEL PSMA-BINDING AGENTS AND USES THEREOF
    Publication number: 20210009715
    Abstract: The present invention provides novel compounds that are useful as radiopharmaceuticals, imaging agents and for treatment of cancer.
    Type: Application
    Filed: May 24, 2018
    Publication date: January 14, 2021
    Inventors: Martina Benesova, Cristina Müller, Christoph Umbricht, Roger Schibli, Konstantin Zhernosekov
  • ISOMERICALLY PURE 18F-LABELLED TETRAHYDROFOLATES
    Publication number: 20200306390
    Abstract: The present invention is directed towards isomerically pure 18F-labelled (6S)- or (6R)-5-methyltetrahydrofolate radiopharmaceuticals, wherein the phenyl group within the folate structure, has been replaced by an 18F-labelled N-heterocycle, for use in diagnostic imaging of a cell or population of cells expressing a folate-receptor in vitro or in vivo or for use in monitoring of cancer or inflammatory and autoimmune diseases and therapy thereof.
    Type: Application
    Filed: March 19, 2018
    Publication date: October 1, 2020
    Applicant: Merck Patent GmbH
    Inventors: Rudolf MOSER, Viola GROEHN, Cristina MUELLER, Roger SCHIBLI, Simon AMETAMEY, Silvan BOSS