Patents by Inventor Cristina TINTORI

Cristina TINTORI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral compounds and use thereof
    Patent number: 11814366
    Abstract: The present invention relates to compounds of formula (I), their use as medicaments, in particular as broad spectrum antiviral agents, their combination with a further antiviral agent and relative pharmaceutical compositions. In particular, the compounds of the invention are useful in the treatment of a disease caused by an enveloped virus.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: November 14, 2023
    Assignee: UNIVERSITA DEGLI STUDI DI SIENA
    Inventors: Maurizio Botta, Filippo Canducci, Valeria Cagno, David Lembo, Cristina Tintori, Annalaura Brai, Nastasja Palombi
  • Use of DDX3 inhibitors as antiproliferative agents
    Patent number: 11000512
    Abstract: The present invention refers to compounds of formula I or II endowed with DDX3 inhibitory activity, relative pharmaceutical compositions and their use as antihyperproliferative agents. (I) or (II).
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: May 11, 2021
    Assignee: AZIENDA OSPEDALIERA UNIVERSITARIA SENESE
    Inventors: Annalaura Brai, Maurizio Botta, Cristina Tintori, Giovanni Maga
  • ANTIVIRAL COMPOUNDS AND USE THEREOF
    Publication number: 20210070737
    Abstract: The present invention relates to compounds of formula (I), their use as medicaments, in particular as broad spectrum antiviral agents, their combination with a further antiviral agent and relative pharmaceutical compositions. In particular, the compounds of the invention are useful in the treatment of a disease caused by an enveloped virus.
    Type: Application
    Filed: March 18, 2019
    Publication date: March 11, 2021
    Applicant: UNIVERSITA DEGLE STUDI DI SIENA
    Inventors: Maurizio BOTTA, Filippo CANDUCCI, Valeria CAGNO, David LEMBO, Cristina TINTORI, Annalaura BRAI, Nastaja PALOMBI
  • Human helicase DDX3 inhibitors as therapeutic agents
    Patent number: 10941121
    Abstract: The present invention refers to compounds endowed with RNA helicase DDX3 inhibitory activity of formula I and II and their therapeutic use, in particular for the treatment of viral diseases.
    Type: Grant
    Filed: January 6, 2020
    Date of Patent: March 9, 2021
    Assignee: AZIENDA OSPEDALIERA UNIVERSITARIA SENESE
    Inventors: Andreas Meyerhans, Miguel Angel Martinez De La Sierra, Annalaura Brai, Roberta Fazi, Cristina Tintori, Maurizio Botta, Jose Este-Araque, Javier Martinez
  • HUMAN HELICASE DDX3 INHIBITORS AS THERAPEUTIC AGENTS
    Publication number: 20200140398
    Abstract: The present invention refers to compounds endowed with RNA helicase DDX3 inhibitory activity of formula I and II and their therapeutic use, in particular for the treatment of viral diseases.
    Type: Application
    Filed: January 6, 2020
    Publication date: May 7, 2020
    Applicant: AZIENDA OSPEDALIERA UNIVERSITARIA SENESE
    Inventors: Andreas MEYERHANS, Miguel-Angel MARTINEZ DE LA SIERRA, Annalaura BRAI, Roberta FAZI, Cristina TINTORI, Maurizio BOTTA, Jose-Este ARAQUE, Javier MARTINEZ
  • COMPOUNDS AND USES THEREOF
    Publication number: 20180186796
    Abstract: The present invention refers to 4-amino-substituted pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine derivatives of formula I and IV able to target the Src family kinases (SFKs) such as Src, Fyn and Hck tyrosine kinases as well as Abl tyrosine kinase and uses and method of preparation thereof. In particular, the compounds of the invention are for use in the treatment and/or prevention of cancer, such as neuroblastoma (NB) or glioblastoma multiforme (GBM) or for use in the treatment and/or prevention of neurodegenerative diseases such as taupathies.
    Type: Application
    Filed: October 29, 2015
    Publication date: July 5, 2018
    Applicant: LEAD DISCOVERY SIENA S.R.L.
    Inventors: Maurizio BOTTA, Adriano ANGELUCCI, Elena DREASSI, Silvia SCHENONE, Cristina TINTORI, Giulia VIGNAROLI
  • HUMAN HELICASE DDX3 INHIBITORS AS THERAPEUTIC AGENTS
    Publication number: 20180016243
    Abstract: The present invention refers to compounds endowed with RNA helicase DDX3 inhibitory activity of formula I and II and their therapeutic use, in particular for the treatment of viral diseases.
    Type: Application
    Filed: February 12, 2016
    Publication date: January 18, 2018
    Inventors: Andreas MEYERHANS, Miguel-Angel MARTINEZ DE LA SIERRA, Annalaura BRAI, Roberta FAZI, Cristina TINTORI, Maurizio BOTTA, Jose-Este ARAQUE, Javier MARTINEZ