Abstract: An automated process development device providing flexibility and accuracy for the investigative development of tangential flow filtration (tff) processes and used for evaluating the process parameters of a laboratory scale tff process with an eye towards developing a commercial scale process. The device—operable to a recirculation volume of less than 20 milliliters—includes: a reservoir having a distinct mixing zone; a tff module; conduits defining a fluid process stream through which a liquid sample is recirculated; pumps for driving and valves for regulating the flow of the liquid sample through the stream; sensors for acquiring data about the sample as it flows through the stream; and an electronic data processing network capable of receiving, transmitting, processing, and recording data associated with the operation of the pumps, valves, and sensors, the recorded data being sufficiently comprehensive to determine the conduct of the tangential flow filtration process at a substantially larger scale.

Abstract: The present invention provides an operation editor that includes a user interface for programming operations to be performed by a chemical process machine. Through the user interface the user may specify that one or more of the steps in an operation be variable. Such variable steps may subsequently be edited by the same or another user when the operation is incorporated into a procedure. Steps in the operation that are not variable are fixed and may not be edited when the operation has been incorporated into a procedure. Furthermore, individual fields in a variable step may be either variable or fixed. The present invention also provides a procedure editor that includes a user interface, which allows the user to edit variable steps within the procedure's operations. The procedure editor presents to the user for editing only those steps within the procedure that are variable.

Abstract: An automated process development device providing flexibility and accuracy for the investigative development of tangential flow filtration processes. The development device is used for evaluating the process parameters of a laboratory scale tangential flow filtration process with an eye towards developing a larger, commercial scale process.

Abstract: An automated fluid filtration system is disclosed, the system providing flexibility and accuracy for the investigative development of liquid separation processes. The system can be used for optimizing the protocol parameters of laboratory scale separation processes towards larger, commercial scale processes.

Abstract: The present invention provides an operation editor that includes a user interface for programming operations to be performed by a chemical process machine. Through the user interface the user may specify that one or more of the steps in an operation be variable. Such variable steps may subsequently be edited by the same or another user when the operation is incorporated into a procedure. Steps in the operation that are not variable are fixed and may not be edited when the operation has been incorporated into a procedure. Furthermore, individual fields in a variable step may be either variable or fixed. The present invention also provides a procedure editor that includes a user interface, which allows the user to edit variable steps within the procedure's operations. The procedure editor presents to the user for editing only those steps within the procedure that are variable.

Abstract: A tangential flow filtration apparatus is provided which includes a liquid feed reservoir and a tangential flow filtration module connected together by manifolds. The manifolds eliminate the need for tubular conduits, thereby effecting a reduction in recirculation volume for the apparatus.

Abstract: A tangential flow filtration apparatus is provided which includes a liquid feed reservoir and a tangential flow filtration module connected together by manifolds. The manifolds eliminate the need for tubular conduits, thereby effecting a reduction in recirculation volume for the apparatus.