Patents by Inventor Crystal Darby

Crystal Darby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • membrane protease as a target for inhibitors of intrabacterial pH homeostasis
    Patent number: 8951992
    Abstract: The present invention is directed to methods and compounds for inhibiting bacterial growth and treating a bacterial infection in a subject. These methods involve providing an inhibitor of intrabacterial pH homeostasis, including inhibitors of the Mycobacterium tuberculosis Rv3671c gene encoded membrane protease. Methods for identifying novel compounds that disrupt intrabacterial pH homeostasis and their use for inhibiting bacterial growth and treating a bacterial infection in a subject are also disclosed.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: February 10, 2015
    Assignee: Cornell University
    Inventors: Carl Nathan, Sabine Ehrt, Omar Vandal, Crystal Darby
  • MYCOBACTERIUM MEMBRANE PROTEASE AS A TARGET FOR INHIBITORS OF INTRABACTERIAL pH HOMEOSTASIS
    Publication number: 20110190234
    Abstract: The present invention is directed to methods and compounds for inhibiting bacterial growth and treating a bacterial infection in a subject. These methods involve providing an inhibitor of intrabacterial pH homeostasis, including inhibitors of the Mycobacterium tuberculosis Rv3671c gene encoded membrane protease. Methods for identifying novel compounds that disrupt intrabacterial pH homeostasis and their use for inhibiting bacterial growth and treating a bacterial infection in a subject are also disclosed.
    Type: Application
    Filed: July 20, 2009
    Publication date: August 4, 2011
    Applicant: CORNELL UNIVERSITY
    Inventors: Carl Nathan, Sabine Ehrt, Omar Vandal, Crystal Darby